TIP regimen: Difference between revisions

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==Overview==
==Overview==
{{PAGENAME}} refers to  a regimen consisting of [[paclitaxel]], [[ifosfamide]], [[mesna]] and [[cisplatin]] used for the treatment of advanced-stage testicular cancer; also used for the treatment of unresectable and recurrent [[head and neck cancer|squamous cell head and neck cancer]].<ref name="pmid16926060">{{cite journal| author=Pohl G, Krajnik G, Malayeri R, Müller RM, Klepetko W, Eckersberger F et al.| title=Induction chemotherapy with the TIP regimen (paclitaxel/ifosfamide/cisplatin) in stage III non-small cell lung cancer. | journal=Lung Cancer | year= 2006 | volume= 54 | issue= 1 | pages= 63-7 | pmid=16926060 | doi=10.1016/j.lungcan.2006.05.027 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16926060 }} </ref>
{{PAGENAME}} refers to  a regimen consisting of [[paclitaxel]], [[ifosfamide]], [[mesna]] and [[cisplatin]] used for the treatment of advanced-stage [[testicular cancer]]<ref name="pmid16170162">{{cite journal| author=Kondagunta GV, Bacik J, Donadio A, Bajorin D, Marion S, Sheinfeld J et al.| title=Combination of paclitaxel, ifosfamide, and cisplatin is an effective second-line therapy for patients with relapsed testicular germ cell tumors. | journal=J Clin Oncol | year= 2005 | volume= 23 | issue= 27 | pages= 6549-55 | pmid=16170162 | doi=10.1200/JCO.2005.19.638 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16170162  }} </ref>; also used for the treatment of unresectable and recurrent [[head and neck cancer|squamous cell head and neck cancer]].<ref name="pmid10697043">{{cite journal| author=Shin DM| title=Paclitaxel (Taxol)/ifosfamide-based chemotherapy in patients with recurrent or metastatic squamous cell carcinoma of the head and neck. | journal=Semin Oncol | year= 2000 | volume= 27 | issue= 1 Suppl 1 | pages= 36-40 | pmid=10697043 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10697043  }} </ref>


==Regimen==
==Regimen==
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==Indications==
==Indications==
*[[head and neck cancer|squamous cell head and neck cancer]]<ref name="pmid16926060">{{cite journal| author=Pohl G, Krajnik G, Malayeri R, Müller RM, Klepetko W, Eckersberger F et al.| title=Induction chemotherapy with the TIP regimen (paclitaxel/ifosfamide/cisplatin) in stage III non-small cell lung cancer. | journal=Lung Cancer | year= 2006 | volume= 54 | issue= 1 | pages= 63-7 | pmid=16926060 | doi=10.1016/j.lungcan.2006.05.027 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16926060 }} </ref><ref>{{Cite web | title = NCI Thesaurus | accessdate =  | url = http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C63490&ns=NCI_Thesaurus}}</ref>
*[[testicular cancer|Advanced-stage testicular cancer]]<ref name="pmid16170162">{{cite journal| author=Kondagunta GV, Bacik J, Donadio A, Bajorin D, Marion S, Sheinfeld J et al.| title=Combination of paclitaxel, ifosfamide, and cisplatin is an effective second-line therapy for patients with relapsed testicular germ cell tumors. | journal=J Clin Oncol | year= 2005 | volume= 23 | issue= 27 | pages= 6549-55 | pmid=16170162 | doi=10.1200/JCO.2005.19.638 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16170162  }} </ref>, [[head and neck cancer|Squamous cell head and neck cancer]]<ref name="pmid10697043">{{cite journal| author=Shin DM| title=Paclitaxel (Taxol)/ifosfamide-based chemotherapy in patients with recurrent or metastatic squamous cell carcinoma of the head and neck. | journal=Semin Oncol | year= 2000 | volume= 27 | issue= 1 Suppl 1 | pages= 36-40 | pmid=10697043 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10697043  }} </ref><ref>{{Cite web | title = NCI Thesaurus | accessdate =  | url = http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C63490&ns=NCI_Thesaurus}}</ref>


==References==
==References==

Latest revision as of 15:08, 30 March 2015

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aparna Vuppala, M.B.B.S. [2]

Synonyms and keywords:Taxol-Ifosfamide-Platinol Regimen; TIP Regimen

Overview

TIP regimen refers to a regimen consisting of paclitaxel, ifosfamide, mesna and cisplatin used for the treatment of advanced-stage testicular cancer[1]; also used for the treatment of unresectable and recurrent squamous cell head and neck cancer.[2]

Regimen

TTaxol (paclitaxel)

IIfosfamide

PPlatinol (cisplatin)

Indications

References

  1. 1.0 1.1 Kondagunta GV, Bacik J, Donadio A, Bajorin D, Marion S, Sheinfeld J; et al. (2005). "Combination of paclitaxel, ifosfamide, and cisplatin is an effective second-line therapy for patients with relapsed testicular germ cell tumors". J Clin Oncol. 23 (27): 6549–55. doi:10.1200/JCO.2005.19.638. PMID 16170162.
  2. 2.0 2.1 Shin DM (2000). "Paclitaxel (Taxol)/ifosfamide-based chemotherapy in patients with recurrent or metastatic squamous cell carcinoma of the head and neck". Semin Oncol. 27 (1 Suppl 1): 36–40. PMID 10697043.
  3. "NCI Thesaurus".