TCH regimen: Difference between revisions

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Latest revision as of 15:47, 30 March 2015

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aparna Vuppala, M.B.B.S. [2]

Synonyms and keywords:Docetaxel-Carboplatin-Trastuzumab Regimen; Taxotere-Carboplatin-Herceptin Regimen; TCH Regimen

Overview

TCH regimen refers to a sequential regimen consisting of multiple cycles of docetaxel (taxotere), carboplatin and trastuzumab (herceptin), followed by multiple cycles of trastuzumab alone, administered as a dose-dense regimen, and used in the adjuvant setting for the treatment of HER-2/neu-positive breast cancer.^[1]^[2]

Regimen

TDocetaxel (Taxotere)

CCarboplatin

HTrastuzumab (Herceptin)

Indications

HER-2/neu-positive breast cancer.^[1]

References

↑ ^1.0 ^1.1 Slamon D, Eiermann W, Robert N, Pienkowski T, Martin M, Press M; et al. (2011). "Adjuvant trastuzumab in HER2-positive breast cancer". N Engl J Med. 365 (14): 1273–83. doi:10.1056/NEJMoa0910383. PMC 3268553. PMID 21991949.
↑ "NCI Thesaurus".

[pmid21991949-1] 1.0 ^1.1 Slamon D, Eiermann W, Robert N, Pienkowski T, Martin M, Press M; et al. (2011). "Adjuvant trastuzumab in HER2-positive breast cancer". N Engl J Med. 365 (14): 1273–83. doi:10.1056/NEJMoa0910383. PMC 3268553. PMID 21991949.

[2] "NCI Thesaurus".

[1]

[2]

@@ Line 9: / Line 9: @@
 ==Regimen==
 {{chemo|T|Docetaxel (Taxotere)}}
@@ Line 18: / Line 17: @@
 ==Indications==
 *HER-2/neu-positive [[breast cancer]].<ref name="pmid21991949">{{cite journal| author=Slamon D, Eiermann W, Robert N, Pienkowski T, Martin M, Press M et al.| title=Adjuvant trastuzumab in HER2-positive breast cancer. | journal=N Engl J Med | year= 2011 | volume= 365 | issue= 14 | pages= 1273-83 | pmid=21991949 | doi=10.1056/NEJMoa0910383 | pmc=PMC3268553 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21991949 }} </ref>
 ==References==
 {{Reflist|2}}
 [[Category:Chemotherapy regimens]]