R-GCVP regimen: Difference between revisions

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==Overview==
==Overview==
{{PAGENAME}} refers to a regimen consisting of [[rituximab]], [[gemcitabine]], [[cyclophosphamide]], [[vincristine|vincristine (Oncovin)]], and [[prednisone]] used to treat both indolent and aggressive forms of [[diffuse large B-cell lymphoma]].<ref name="pmid18270861">{{cite journal| author=Carbone J, Perez-Fernandez R, Muñoz A, Sabin P, Carreño L, Fernandez-Cruz E| title=Combined therapy with rituximab plus cyclophosphamide/vincristine/prednisone for Sjogren's syndrome-associated B-cell non-Hodgkin's lymphoma. | journal=Clin Rev Allergy Immunol | year= 2008 | volume= 34 | issue= 1 | pages= 80-4 | pmid=18270861 | doi=10.1007/s12016-007-8025-2 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18270861 }} </ref>
{{PAGENAME}} refers to a regimen consisting of [[rituximab]], [[gemcitabine]], [[cyclophosphamide]], [[vincristine|vincristine (Oncovin)]], and [[prednisone]] used to treat both indolent and aggressive forms of [[diffuse large B-cell lymphoma]].<ref name="pmid24220559">{{cite journal| author=Fields PA, Townsend W, Webb A, Counsell N, Pocock C, Smith P et al.| title=De novo treatment of diffuse large B-cell lymphoma with rituximab, cyclophosphamide, vincristine, gemcitabine, and prednisolone in patients with cardiac comorbidity: a United Kingdom National Cancer Research Institute trial. | journal=J Clin Oncol | year= 2014 | volume= 32 | issue= 4 | pages= 282-7 | pmid=24220559 | doi=10.1200/JCO.2013.49.7586 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24220559 }} </ref>


==Regimen==
==Regimen==
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==Indications==
==Indications==
* [[Diffuse large B-cell lymphoma]].<ref name="pmid18270861">{{cite journal| author=Carbone J, Perez-Fernandez R, Muñoz A, Sabin P, Carreño L, Fernandez-Cruz E| title=Combined therapy with rituximab plus cyclophosphamide/vincristine/prednisone for Sjogren's syndrome-associated B-cell non-Hodgkin's lymphoma. | journal=Clin Rev Allergy Immunol | year= 2008 | volume= 34 | issue= 1 | pages= 80-4 | pmid=18270861 | doi=10.1007/s12016-007-8025-2 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18270861 }} </ref>
* [[Diffuse large B-cell lymphoma]].<ref name="pmid24220559">{{cite journal| author=Fields PA, Townsend W, Webb A, Counsell N, Pocock C, Smith P et al.| title=De novo treatment of diffuse large B-cell lymphoma with rituximab, cyclophosphamide, vincristine, gemcitabine, and prednisolone in patients with cardiac comorbidity: a United Kingdom National Cancer Research Institute trial. | journal=J Clin Oncol | year= 2014 | volume= 32 | issue= 4 | pages= 282-7 | pmid=24220559 | doi=10.1200/JCO.2013.49.7586 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24220559 }} </ref>


==References==
==References==

Latest revision as of 18:29, 31 March 2015

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aparna Vuppala, M.B.B.S. [2]

Synonyms and keywords: Rituximab-Gemcitabine-Cyclophosphamide-Vincristine-Prednisone regimen

Overview

R-GCVP regimen refers to a regimen consisting of rituximab, gemcitabine, cyclophosphamide, vincristine (Oncovin), and prednisone used to treat both indolent and aggressive forms of diffuse large B-cell lymphoma.[1]

Regimen

RRituximab

GGemcitabine

CCyclophosphamide

VVincristine (Oncovin)

PPrednisone

Indications

References

  1. 1.0 1.1 Fields PA, Townsend W, Webb A, Counsell N, Pocock C, Smith P; et al. (2014). "De novo treatment of diffuse large B-cell lymphoma with rituximab, cyclophosphamide, vincristine, gemcitabine, and prednisolone in patients with cardiac comorbidity: a United Kingdom National Cancer Research Institute trial". J Clin Oncol. 32 (4): 282–7. doi:10.1200/JCO.2013.49.7586. PMID 24220559.