Proglumetacin: Difference between revisions
No edit summary |
No edit summary |
||
| Line 25: | Line 25: | ||
| routes_of_administration = | | routes_of_administration = | ||
}} | }} | ||
__NOTOC__ | |||
{{SI}} | |||
{{CMG}} | |||
==Overview== | |||
'''Proglumetacin''' (usually as the [[maleate]] salt, trade names '''Afloxan''', '''Protaxon''' and '''Proxil''') is a [[non-steroidal anti-inflammatory drug]]. It is [[drug metabolism|metabolized]] in the body to [[indometacin]] and [[proglumide]],<ref>{{cite journal |author=Setnikar I, Arigoni R, Chisté R, Makovec F, Revel L |title=Plasma levels of proglumetacin and its metabolites after intravenous or oral administration in the dog |journal=Arzneimittel-Forschung |volume=37 |issue=6 |pages=698–702 |year=1987 |pmid=3663267 |doi=}}</ref> a drug with [[wikt:antisecretory|antisecretory]] effects that helps prevent injury to the stomach lining. | '''Proglumetacin''' (usually as the [[maleate]] salt, trade names '''Afloxan''', '''Protaxon''' and '''Proxil''') is a [[non-steroidal anti-inflammatory drug]]. It is [[drug metabolism|metabolized]] in the body to [[indometacin]] and [[proglumide]],<ref>{{cite journal |author=Setnikar I, Arigoni R, Chisté R, Makovec F, Revel L |title=Plasma levels of proglumetacin and its metabolites after intravenous or oral administration in the dog |journal=Arzneimittel-Forschung |volume=37 |issue=6 |pages=698–702 |year=1987 |pmid=3663267 |doi=}}</ref> a drug with [[wikt:antisecretory|antisecretory]] effects that helps prevent injury to the stomach lining. | ||
==References== | ==References== | ||
{{Reflist}} | {{Reflist|2}} | ||
[[Category:Non-steroidal anti-inflammatory drugs]] | [[Category:Non-steroidal anti-inflammatory drugs]] | ||
[[Category:Prodrugs]] | [[Category:Prodrugs]] | ||
[[Category:Drugs]] | [[Category:Drugs]] | ||
Latest revision as of 20:10, 6 April 2015
 | |
| Clinical data | |
|---|---|
| ATC code | |
| Pharmacokinetic data | |
| Metabolism | Hepatic. Undergoes enterohepatic recirculation |
| Identifiers | |
| |
| CAS Number | |
| PubChem CID | |
| E number | {{#property:P628}} |
| ECHA InfoCard | {{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value). |
| Chemical and physical data | |
| Formula | C46H58ClN5O8 |
| Molar mass | 844.43442 g/mol |
|
WikiDoc Resources for Proglumetacin |
|
Articles |
|---|
|
Most recent articles on Proglumetacin Most cited articles on Proglumetacin |
|
Media |
|
Powerpoint slides on Proglumetacin |
|
Evidence Based Medicine |
|
Clinical Trials |
|
Ongoing Trials on Proglumetacin at Clinical Trials.gov Trial results on Proglumetacin Clinical Trials on Proglumetacin at Google
|
|
Guidelines / Policies / Govt |
|
US National Guidelines Clearinghouse on Proglumetacin NICE Guidance on Proglumetacin
|
|
Books |
|
News |
|
Commentary |
|
Definitions |
|
Patient Resources / Community |
|
Patient resources on Proglumetacin Discussion groups on Proglumetacin Patient Handouts on Proglumetacin Directions to Hospitals Treating Proglumetacin Risk calculators and risk factors for Proglumetacin
|
|
Healthcare Provider Resources |
|
Causes & Risk Factors for Proglumetacin |
|
Continuing Medical Education (CME) |
|
International |
|
|
|
Business |
|
Experimental / Informatics |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Proglumetacin (usually as the maleate salt, trade names Afloxan, Protaxon and Proxil) is a non-steroidal anti-inflammatory drug. It is metabolized in the body to indometacin and proglumide,[1] a drug with antisecretory effects that helps prevent injury to the stomach lining.
References
- Pages with script errors
- CS1 maint: Multiple names: authors list
- E number from Wikidata
- ECHA InfoCard ID from Wikidata
- Articles without EBI source
- Chemical pages without ChemSpiderID
- Chemical pages without DrugBank identifier
- Articles without KEGG source
- Articles without InChI source
- Articles without UNII source
- Drugs with no legal status
- Articles containing unverified chemical infoboxes
- Non-steroidal anti-inflammatory drugs
- Prodrugs
- Drugs