Succinylsulfathiazole: Difference between revisions
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{{Drugbox | {{Drugbox | ||
| IUPAC_name | | Watchedfields = changed | ||
| image | | verifiedrevid = 443214593 | ||
| IUPAC_name = 4-oxo-4-({4-[(1,3-thiazol-2-ylamino)sulfonyl]phenyl}amino)butanoic acid | |||
| image = Succinylsulfathiazole.png | |||
| | |||
<!--Clinical data--> | |||
| tradename = | |||
| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X --> | |||
| pregnancy_US = <!-- A / B / C / D / X --> | |||
| pregnancy_category = | |||
| legal_AU = <!-- Unscheduled / S2 / S3 / S4 / S5 / S6 / S7 / S8 / S9 --> | |||
| legal_CA = <!-- / Schedule I, II, III, IV, V, VI, VII, VIII --> | |||
| legal_UK = <!-- GSL / P / POM / CD / Class A, B, C --> | |||
| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V --> | |||
| pregnancy_AU | | legal_status = | ||
| pregnancy_US | | routes_of_administration = | ||
| pregnancy_category= | |||
| legal_AU | <!--Pharmacokinetic data--> | ||
| legal_CA | | bioavailability = | ||
| legal_UK | | protein_bound = | ||
| legal_US | | metabolism = | ||
| legal_status | | elimination_half-life = | ||
| routes_of_administration = | | excretion = | ||
<!--Identifiers--> | |||
| CAS_number = | |||
| ATC_prefix = A07 | |||
| ATC_suffix = AB04 | |||
| PubChem = 5315 | |||
| DrugBank_Ref = {{drugbankcite|correct|drugbank}} | |||
| DrugBank = | |||
| ChEMBL = 1484857 | |||
| UNII_Ref = {{fdacite|correct|FDA}} | |||
| UNII = RSS8647O4S | |||
| KEGG_Ref = {{keggcite|correct|kegg}} | |||
| KEGG = D07060 | |||
<!--Chemical data--> | |||
| C=13 | H=13 | N=3 | O=5 | S=2 | |||
| molecular_weight = 355.38942 g/mol | |||
}} | }} | ||
'''Succinylsulfathiazole''' is a [[Sulfonamide (medicine)|sulfonamide]]. It is also spelled as succinylsulphathiazole. It is a white or yellow-white crystalline powder. It dissolves in aqueous solutions of alkali hydroxides and carbonates but is very slightly soluble in water. | |||
It is classified as ultra long acting drug. About 95% of the drug remains in the intestine and only 5% is hydrolyzed, slowly, to [[Sulfathiazole]] and is absorbed. | |||
The drug is used for its antibacterial activity in the GIT. The dose is 10g - 20g daily in divided doses. | |||
{{Antidiarrheals, intestinal anti-inflammatory/anti-infective agents}} | {{Antidiarrheals, intestinal anti-inflammatory/anti-infective agents}} | ||
[[Category:Thiazoles]] | [[Category:Thiazoles]] | ||
[[Category:Sulfonamide antibiotics]] | |||
[[Category:Anilides]] | |||
Latest revision as of 19:06, 7 April 2015
Clinical data | |
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ATC code | |
Identifiers | |
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PubChem CID | |
UNII | |
KEGG | |
ChEMBL | |
E number | {{#property:P628}} |
ECHA InfoCard | {{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value). |
Chemical and physical data | |
Formula | C13H13N3O5S2 |
Molar mass | 355.38942 g/mol |
(verify) |
Succinylsulfathiazole is a sulfonamide. It is also spelled as succinylsulphathiazole. It is a white or yellow-white crystalline powder. It dissolves in aqueous solutions of alkali hydroxides and carbonates but is very slightly soluble in water.
It is classified as ultra long acting drug. About 95% of the drug remains in the intestine and only 5% is hydrolyzed, slowly, to Sulfathiazole and is absorbed.
The drug is used for its antibacterial activity in the GIT. The dose is 10g - 20g daily in divided doses.
Template:Antidiarrheals, intestinal anti-inflammatory/anti-infective agents
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- Thiazoles
- Sulfonamide antibiotics
- Anilides