Pipamperone: Difference between revisions

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Pipamperone
Clinical data
AHFS/Drugs.com	International Drug Names
Routes of; administration	Oral
ATC code	N05AD05 (WHO) ;
Identifiers
	IUPAC name 1'-[4-(4-fluorophenyl)-4-oxobutyl]-1,4'-bipiperidine-4'-carboxamide;
CAS Number	1893-33-0 ;
PubChem CID	4830;
IUPHAR/BPS	92;
ChemSpider	4664 ;
UNII	5402501F0W;
KEGG	D02622 ;
ChEMBL	ChEMBL440294 ;
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C21H30FN3O2
Molar mass	375.480 g/mol
3D model (JSmol)	Interactive image;
	SMILES Fc1ccc(cc1)C(=O)CCCN3CCC(C(=O)N)(N2CCCCC2)CC3;
	InChI InChI=1S/C21H30FN3O2/c22-18-8-6-17(7-9-18)19(26)5-4-12-24-15-10-21(11-16-24,20(23)27)25-13-2-1-3-14-25/h6-9H,1-5,10-16H2,(H2,23,27) ; Key:AXKPFOAXAHJUAG-UHFFFAOYSA-N ;
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VisualWikitext

Latest revision as of 15:53, 9 April 2015

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Pipamperone is an antipsychotic drug (a butyrophenone derivative) used in the treatment of schizophrenia. Pipamperone is known to the general public under the marketed brand name Dipiperon. It was discovered at Janssen Pharmaceutica in 1960.

References

@@ Line 1: / Line 1: @@
-{{Drugbox|
+{{Drugbox
-| IUPAC_name = ''1-[4-(4-fluorophenyl)-4-oxo-butyl]-4-(1-piperidyl)piperidine-4-carboxamide''
+| Verifiedfields = changed
-| image = Pipamperone.png
+| verifiedrevid = 464207244
+| IUPAC_name = 1'-[4-(4-fluorophenyl)-4-oxobutyl]-1,4'-bipiperidine-4'-carboxamide
+| image = Pipamperone1.png
 | width = 140
-| CAS_number =
+<!--Clinical data-->
+| tradename =
+| Drugs.com = {{drugs.com|international|pipamperone}}
+| pregnancy_AU =
+| pregnancy_US =
+| legal_status =
+| routes_of_administration = Oral
+<!--Pharmacokinetic data-->
+| bioavailability =
+| metabolism =
+| elimination_half-life =
+| excretion =
+<!--Identifiers-->
+| CAS_number_Ref = {{cascite|changed|??}}
+| CAS_number = 1893-33-0
 | ATC_prefix = N05
 | ATC_suffix = AD05
 | ATC_supplemental =
 | PubChem = 4830
-| DrugBank =
+| IUPHAR_ligand = 92
-| C = 21 | H = 30 | F = 1 | N = 3 | O = 2
+| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
+| DrugBank =
+| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
+| ChemSpiderID = 4664
+| UNII_Ref = {{fdacite|correct|FDA}}
+| UNII = 5402501F0W
+| KEGG_Ref = {{keggcite|correct|kegg}}
+| KEGG = D02622
+| ChEMBL_Ref = {{ebicite|correct|EBI}}
+| ChEMBL = 440294
+<!--Chemical data-->
+| C=21 | H=30 | F=1 | N=3 | O=2
 | molecular_weight = 375.480 g/mol
-| bioavailability =
+| smiles = Fc1ccc(cc1)C(=O)CCCN3CCC(C(=O)N)(N2CCCCC2)CC3
-| metabolism =
+| InChI = 1/C21H30FN3O2/c22-18-8-6-17(7-9-18)19(26)5-4-12-24-15-10-21(11-16-24,20(23)27)25-13-2-1-3-14-25/h6-9H,1-5,10-16H2,(H2,23,27)
-| elimination_half-life =
+| InChIKey = AXKPFOAXAHJUAG-UHFFFAOYAL
-| excretion =
+| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
-| pregnancy_AU =
+| StdInChI = 1S/C21H30FN3O2/c22-18-8-6-17(7-9-18)19(26)5-4-12-24-15-10-21(11-16-24,20(23)27)25-13-2-1-3-14-25/h6-9H,1-5,10-16H2,(H2,23,27)
-| pregnancy_US =
+| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
-| legal_status =
+| StdInChIKey = AXKPFOAXAHJUAG-UHFFFAOYSA-N
-| routes_of_administration = Oral
 }}
-'''Pipamperone''' is an [[antipsychotic]] [[drug]] (a [[butyrophenone]] derivative) used in the treatment of [[schizophrenia]]. Pipamperone is known to the general public under the marketed brand name Dipiperon®.
+__NOTOC__
+{{SI}}
-Pipamperone was discovered at [[Janssen Pharmaceutica]] in [[1960]].
+{{CMG}}
+==Overview==
+'''Pipamperone''' is an [[antipsychotic]] [[drug]] (a [[butyrophenone]] derivative) used in the treatment of [[schizophrenia]]. Pipamperone is known to the general public under the marketed brand name Dipiperon. It was discovered at [[Janssen Pharmaceutica]] in 1960.
+[[File:Pipamperon.JPG|none|left|350px]]
+==See also==
+*[[Piritramide]]
 ==References==
-* Fouks, Mathis, Gilbert, Ferragu, Houssait, Lerno, Treatment of character disorders with a new butyrophenone: R. 3345 or pipamperone, Ann Med Psychol (Paris). 1966 Dec;124(5):677-81.
+{{Reflist|2}}
-* Deberdt R., Pipamperone (Dipiperon) in the treatment of behaviour disorders. A large-scale multicentre evaluation,  Acta Psychiatr Belg. 1976 Jan-Feb;76(1):157-66.
+{{Antipsychotics}}
-{{pharma-stub}}
-[[Category:Typical antipsychotics]]
+[[Category:Piperidines]]
-[[de:Pipamperon]]
+[[Category:Amides]]
-[[ja:塩酸フロロピパミド]]
+[[Category:Organofluorides]]
+[[Category:Drug]]

v t e Antipsychotics (neuroleptics) (N05A)
Typical	Benzamides: Levosulpiride • Nemonapride • Sulpiride • Sultopride • Tiapride • Veralipride; Butyrophenones: Azaperone • Benperidol • Bromperidol • Droperidol • Fluanisone • Haloperidol • Lenperone • Moperone • Pipamperone • Spiperone • Timiperone • Trifluperidol; Diphenylbutylpiperidines: Clopimozide • Fluspirilene • Penfluridol • Pimozide; Phenothiazines: Acepromazine • Acetophenazine • Butaperazine • Carphenazine • Chloracizine • Chlorproethazine • Chlorpromazine • Cyamemazine • Dixyrazine • Fluacizine • Fluphenazine • Levomepromazine/Methotrimeprazine • Mesoridazine • Perazine • Periciazine • Perphenazine • Piperacetazine • Pipotiazine • Prochlorperazine • Promazine • Promethazine • Propiomazine • Sulforidazine • Thiethylperazine • Thiopropazate • Thioproperazine • Thioridazine • Trifluoperazine • Triflupromazine; Thioxanthenes: Chlorprothixene • Clopenthixol • Flupentixol • Thiothixene • Zuclopenthixol; Tricyclics: Amoxapine • Butaclamol • Fluotracen • Loxapine • Metitepine/Methiothepin • Octoclothiepin • Trimipramine; Others: Prothipendyl
Atypical	Benzamides: Amisulpride • Remoxipride; Butyrophenones: Cinuperone • Setoperone; Benzo(iso)oxazole piperidines: Iloperidone • Ocaperidone • Paliperidone • Risperidone; Benzo(iso)thiazole piperazines: Lurasidone • Perospirone • Revospirone • Tiospirone • Ziprasidone; Diphenylbutylpiperazines: Amperozide; Phenylpiperazines: Aripiprazole • Bifeprunox • Elopiprazole • Umespirone; Tricyclics: Asenapine • Carpipramine • Clocapramine • Clotiapine • Clozapine • Fluperlapine • Gevotroline • Metitepine/Methiothepin • Mosapramine • NDMC • Olanzapine • Piquindone • Quetiapine • Tenilapine • Zotepine; Others: Blonanserin • Cariprazine • Molindone • Pimavanserin • Roxindole • Sarizotan • Sertindole • Spiramide
Others	Azacyclonol • Cannabidiol • D-Cycloserine • Lithium • Mifepristone • Oxypertine • Reserpine • Rimcazole • Secretin • Talnetant • Tetrabenazine • Vabicaserin
^#WHO-EM ^‡Withdrawn from market Clinical trials: ^†Phase III ^§Never to phase III Template:Psychology navs

Clinical data

AHFS/Drugs.com	International Drug Names
Routes of administration	Oral
ATC code	N05AD05 (WHO)
Identifiers
IUPAC name 1'-[4-(4-fluorophenyl)-4-oxobutyl]-1,4'-bipiperidine-4'-carboxamide
CAS Number	1893-33-0^N
PubChem CID	4830
IUPHAR/BPS	92
ChemSpider	4664^Y
UNII	5402501F0W
KEGG	D02622^Y
ChEMBL	ChEMBL440294^Y
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C₂₁H₃₀FN₃O₂
Molar mass	375.480 g/mol
3D model (JSmol)	Interactive image
SMILES Fc1ccc(cc1)C(=O)CCCN3CCC(C(=O)N)(N2CCCCC2)CC3
InChI InChI=1S/C21H30FN3O2/c22-18-8-6-17(7-9-18)19(26)5-4-12-24-15-10-21(11-16-24,20(23)27)25-13-2-1-3-14-25/h6-9H,1-5,10-16H2,(H2,23,27)^Y Key:AXKPFOAXAHJUAG-UHFFFAOYSA-N^Y
^NY (what is this?) (verify)

Pipamperone: Difference between revisions

Latest revision as of 15:53, 9 April 2015

Overview

See also

References

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