Barbexaclone: Difference between revisions

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Barbexaclone
Combination of
Phenobarbital	Barbiturate
Propylhexedrine	Stimulant (sympathomimetic)
[[{{{component3}}}]]	? Class
[[{{{component4}}}]]	? Class
[[{{{component5}}}]]	? Class
Clinical data
AHFS/Drugs.com	International Drug Names
ATC code	N03AA04 (WHO) ;
Identifiers
CAS Number	4388-82-3 ;
PubChem CID	71196;
DrugBank	DB09001 ;
ChemSpider	64332 ;
UNII	291GX1YB65;
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
3D model (JSmol)	Interactive image;
	SMILES O=C1NC(=O)NC(=O)C1(c2ccccc2)CC.N(C)[C@@H](C)CC1CCCCC1;
	InChI InChI=1S/C12H12N2O3.C10H21N/c1-2-12(8-6-4-3-5-7-8)9(15)13-11(17)14-10(12)16;1-9(11-2)8-10-6-4-3-5-7-10/h3-7H,2H2,1H3,(H2,13,14,15,16,17);9-11H,3-8H2,1-2H3/t;9-/m.0/s1 ; Key:MJCBWPMBFCUHBP-NPULLEENSA-N ;
(what is this?) (verify)

VisualWikitext

Latest revision as of 14:10, 10 April 2015

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Barbexaclone (Maliasin) is a salt compound of phenobarbital and levopropylhexedrine. It was introduced in 1983. It has been reported to be as effective as phenobarbital but better tolerated; however, as of 2004, these "promising results" had not yet been confirmed nor denied in controlled trials. 100 mg of barbexaclone is equivalent to 60 mg of phenobarbital.

References

The Treatment of Epilepsy 2nd Ed by S. D. Shorvon (Editor), David R. Fish (Editor), Emilio Perucca (Editor), W. Edwin Dodson (Editor). Published by Blackwell 2004. p. 472. ISBN 0-632-06046-8

Template:Anticonvulsants Template:Stimulants

@@ Line 1: / Line 1: @@
-{{Drugbox|
+{{Drugbox
-|IUPAC_name = (-)-N,α-Dimethylcyclohexaneethylammonium.5-ethyl-5-phenyl-barbiturate
+| Verifiedfields = changed
-| image=Barbexaclone.png
+| verifiedrevid = 447439675
-| CAS_number=4388-82-3
+| image = Barbexaclon.png
-| ATC_prefix=N03
-| ATC_suffix=AA04
+<!--Combo data-->
-| ATC_supplemental=
+| type = combo
-| PubChem=71196
+| component1 = Phenobarbital
-| DrugBank=
+| class1 = [[Barbiturate]]
-| C=22 | H=33 | N=3 | O=3
+| component2 = Propylhexedrine
-| molecular_weight = 387.52 g/mol
+| class2 = [[Stimulant]] ([[Sympathomimetic drug|sympathomimetic]])
-| bioavailability=
-| metabolism =
+<!--Clinical data-->
-| elimination_half-life=
+| tradename =
-| excretion =
+| Drugs.com = {{drugs.com|international|barbexaclone}}
 | pregnancy_category =
 | legal_status =
-| routes_of_administration=
+| routes_of_administration =
+<!--Identifiers-->
+| CAS_number_Ref = {{cascite|correct|??}}
+| CAS_number = 4388-82-3
+| ATC_prefix = N03
+| ATC_suffix = AA04
+| PubChem = 71196
+| DrugBank_Ref = {{drugbankcite|changed|drugbank}}
+| DrugBank = DB09001
+| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
+| ChemSpiderID = 64332
+| UNII_Ref = {{fdacite|correct|FDA}}
+| UNII = 291GX1YB65
+<!--Chemical data-->
+| smiles = O=C1NC(=O)NC(=O)C1(c2ccccc2)CC.N(C)[C@@H](C)CC1CCCCC1
+| InChI = 1/C12H12N2O3.C10H21N/c1-2-12(8-6-4-3-5-7-8)9(15)13-11(17)14-10(12)16;1-9(11-2)8-10-6-4-3-5-7-10/h3-7H,2H2,1H3,(H2,13,14,15,16,17);9-11H,3-8H2,1-2H3/t;9-/m.0/s1
+| InChIKey = MJCBWPMBFCUHBP-NPULLEENBB
+| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
+| StdInChI = 1S/C12H12N2O3.C10H21N/c1-2-12(8-6-4-3-5-7-8)9(15)13-11(17)14-10(12)16;1-9(11-2)8-10-6-4-3-5-7-10/h3-7H,2H2,1H3,(H2,13,14,15,16,17);9-11H,3-8H2,1-2H3/t;9-/m.0/s1
+| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
+| StdInChIKey = MJCBWPMBFCUHBP-NPULLEENSA-N
 }}
-'''Barbexaclone''' (marketed in Italy as '''Maliasin''' by [[Abbott Laboratories]]) is a salt compound of [[phenobarbital]] and [[propylhexedrine]]. It was introduced in 1983. It is reported to be as effective as phenobarbital but better tolerated. 100&nbsp;mg of barbexaclone is equivalent to 60&nbsp;mg of phenobarbital. It is not available on prescription in the UK or U.S.
+              __NOTOC__
+{{SI}}
+{{CMG}}
-==References==
+==Overview==
+'''Barbexaclone''' ('''Maliasin''') is a salt compound of [[phenobarbital]] and [[levopropylhexedrine]]. It was introduced in 1983. It has been reported to be as effective as phenobarbital but better tolerated; however, as of 2004, these "promising results" had not yet been confirmed nor denied in controlled trials. 100 mg of barbexaclone is equivalent to 60 mg of phenobarbital.
-* ''The Treatment of Epilepsy 2nd Ed'' by S. D. Shorvon (Editor), David R. Fish (Editor), Emilio Perucca (Editor), W. Edwin Dodson (Editor). Published by Blackwell 2004. ISBN 0-632-06046-8
+== References ==
+{{Reflist|2}}
+* ''The Treatment of Epilepsy 2nd Ed'' by S. D. Shorvon (Editor), David R. Fish (Editor), Emilio Perucca (Editor), W. Edwin Dodson (Editor). Published by Blackwell 2004. [http://books.google.com/books?id=TfrwxdXcmosC&pg=PA472&dq=barbexaclone+intitle:epilepsy+inauthor:shorvon&hl=en&ei=gVvMTMGnC4uOjAeeyO3WBw&sa=X&oi=book_result&ct=result&resnum=1&ved=0CCkQ6AEwAA#v=onepage&q=barbexaclone%20intitle%3Aepilepsy%20inauthor%3Ashorvon&f=false p. 472]. ISBN 0-632-06046-8
-{{Barbiturates}}
-[[Category:Barbiturates]]
+{{Anticonvulsants}}
-[[Category:Anticonvulsants]]
+{{Stimulants}}
-{{pharma-stub}}
+[[Category:Barbiturates]]
-[[de:Barbexaclon]]
+[[Category:Drug]]
-{{WikiDoc Help Menu}}
-{{WikiDoc Sources}}

Barbexaclone: Difference between revisions

Latest revision as of 14:10, 10 April 2015

Overview

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