Sulfisomidine: Difference between revisions

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Sulfisomidine
Clinical data
Routes of; administration	Oral
ATC code	J01EB01 (WHO) ;
Pharmacokinetic data
Metabolism	Minor acetylation
Excretion	Renal, 85%
Identifiers
	IUPAC name 4-amino-N-(2,6-dimethylpyrimidin-4-yl); benzenesulfonamide;
CAS Number	515-64-0 ;
PubChem CID	5343;
ChemSpider	5150 ;
UNII	W03L3ODK6E;
KEGG	D01526 ;
ChEBI	CHEBI:32166 ;
ChEMBL	ChEMBL485696 ;
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C12H14N4O2S
Molar mass	278.331 g/mol
3D model (JSmol)	Interactive image;
	SMILES O=S(=O)(Nc1nc(nc(c1)C)C)c2ccc(N)cc2;
	InChI InChI=1S/C12H14N4O2S/c1-8-7-12(15-9(2)14-8)16-19(17,18)11-5-3-10(13)4-6-11/h3-7H,13H2,1-2H3,(H,14,15,16) ; Key:YZMCKZRAOLZXAZ-UHFFFAOYSA-N ;
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VisualWikitext

Latest revision as of 13:06, 15 April 2015

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Sulfisomidine (INN), also known as sulphasomidine (BAN until 2003),^[1] sulfamethin and sulfaisodimidine, is a sulfonamide antibacterial. It is closely related to sulfadimidine.

References

↑ Template:PDFlink. United Kingdom Medicines and Healthcare products Regulatory Agency (December 12, 2003). Retrieved on 2007-08-26 through Archive.org.

External links

Melander A, Bitzén PO, Olsson S (1982). "Therapeutic equivalence of sulfaisodimidine 2 g twice daily and 1 g four times daily in lower urinary tract infections". Acta medica Scandinavica. 211 (5): 361–4. doi:10.1111/j.0954-6820.1982.tb01962.x. PMID 7051761.

Template:Sulfonamides and trimethoprim

[1] Template:PDFlink. United Kingdom Medicines and Healthcare products Regulatory Agency (December 12, 2003). Retrieved on 2007-08-26 through Archive.org.

[1]

@@ Line 1: / Line 1: @@
 {{Drugbox
-| IUPAC_name        = 4-amino-''N''-(2,6-dimethylpyrimidin-4-yl)<br>benzenesulfonamide
+| Verifiedfields = changed
-| image             = Sulfisomidine.svg
+| verifiedrevid = 470473700
-| CAS_number        = 515-64-0
+| IUPAC_name = 4-amino-''N''-(2,6-dimethylpyrimidin-4-yl)<br>benzenesulfonamide
-| ATC_prefix        = J01
+| image = Sulfisomidine.png
-| ATC_suffix        = EB01
+| image2 = Sulfisomidine_ball-and-stick.png
-| PubChem           = 5343
-| DrugBank          =
+<!--Clinical data-->
-| C=12|H=14|N=4|O=2|S=1
+| tradename =
-| molecular_weight  = 278.331 g/mol
+| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X -->
-| bioavailability   =
+| pregnancy_US = <!-- A / B            / C / D / X -->
-| protein_bound     =
+| pregnancy_category =
-| metabolism        = Minor [[acetylation]]
+| legal_AU = <!-- Unscheduled / S2 / S3 / S4 / S5 / S6 / S7 / S8 / S9 -->
-| elimination_half-life =
+| legal_CA = <!--             / Schedule I, II, III, IV, V, VI, VII, VIII -->
-| excretion         = [[Kidney|Renal]], 85%
+| legal_UK = <!-- GSL         / P       / POM / CD / Class A, B, C -->
-| pregnancy_AU      =  <!-- A / B1 / B2 / B3 / C / D / X -->
+| legal_US = <!-- OTC                   / Rx-only  / Schedule I, II, III, IV, V -->
-| pregnancy_US      =  <!-- A / B            / C / D / X -->
+| legal_status =
-| pregnancy_category=
-| legal_AU          =  <!-- Unscheduled / S2 / S3 / S4 / S5 / S6 / S7 / S8 / S9 -->
-| legal_CA          =  <!--             / Schedule I, II, III, IV, V, VI, VII, VIII -->
-| legal_UK          =  <!-- GSL         / P       / POM / CD / Class A, B, C -->
-| legal_US          =  <!-- OTC                   / Rx-only  / Schedule I, II, III, IV, V -->
-| legal_status      =
 | routes_of_administration = Oral
+<!--Pharmacokinetic data-->
+| bioavailability =
+| protein_bound =
+| metabolism = Minor [[acetylation]]
+| elimination_half-life =
+| excretion = [[Kidney|Renal]], 85%
+<!--Identifiers-->
+| CAS_number_Ref = {{cascite|changed|??}}
+| CAS_number = 515-64-0
+| ATC_prefix = J01
+| ATC_suffix = EB01
+| PubChem = 5343
+| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
+| DrugBank =
+| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
+| ChemSpiderID = 5150
+| UNII_Ref = {{fdacite|correct|FDA}}
+| UNII = W03L3ODK6E
+| KEGG_Ref = {{keggcite|correct|kegg}}
+| KEGG = D01526
+| ChEBI_Ref = {{ebicite|correct|EBI}}
+| ChEBI = 32166
+| ChEMBL_Ref = {{ebicite|correct|EBI}}
+| ChEMBL = 485696
+<!--Chemical data-->
+| C=12 | H=14 | N=4 | O=2 | S=1
+| molecular_weight = 278.331 g/mol
+| smiles = O=S(=O)(Nc1nc(nc(c1)C)C)c2ccc(N)cc2
+| InChI = 1/C12H14N4O2S/c1-8-7-12(15-9(2)14-8)16-19(17,18)11-5-3-10(13)4-6-11/h3-7H,13H2,1-2H3,(H,14,15,16)
+| InChIKey = YZMCKZRAOLZXAZ-UHFFFAOYAI
+| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
+| StdInChI = 1S/C12H14N4O2S/c1-8-7-12(15-9(2)14-8)16-19(17,18)11-5-3-10(13)4-6-11/h3-7H,13H2,1-2H3,(H,14,15,16)
+| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
+| StdInChIKey = YZMCKZRAOLZXAZ-UHFFFAOYSA-N
 }}
+                     __NOTOC__
 {{SI}}
+{{CMG}}
+==Overview==
 '''Sulfisomidine''' ([[International Nonproprietary Name|INN]]), also known as '''sulphasomidine''' ([[British Approved Name|BAN]] until 2003),<ref>
-{{PDFlink|[http://web.archive.org/web/20050827062201/medicines.mhra.gov.uk/inforesources/productinfo/banslist.pdf  Changing substance names from BANs to rINNs.]|34.5&nbsp;[[Kibibyte|KiB]]<!-- application/pdf, 35419 bytes -->}}. [[United Kingdom]] [[Medicines and Healthcare products Regulatory Agency]] ([[December 12]] [[2003]]). Retrieved on [[2007-08-26]] through [[Archive.org]].</ref> '''sulfamethin''' and '''sulfaisodimidine''', is a [[sulfonamide]] [[antibacterial]]. It is closely related to [[sulfadimidine]].
+{{PDFlink|[http://web.archive.org/web/20050827062201/medicines.mhra.gov.uk/inforesources/productinfo/banslist.pdf  Changing substance names from BANs to rINNs.]|34.5&nbsp;[[Kibibyte|KiB]]<!-- application/pdf, 35419 bytes -->}}. [[United Kingdom]] [[Medicines and Healthcare products Regulatory Agency]] (December 12, 2003). Retrieved on 2007-08-26 through [[Archive.org]].</ref> '''sulfamethin''' and '''sulfaisodimidine''', is a [[sulfonamide (medicine)|sulfonamide]] [[antibacterial]]. It is closely related to [[sulfadimidine]].
 ==References==
-{{Reflist}}
+{{Reflist|2}}
 ==External links==
-* {{cite journal |author=Melander A, Bitzén PO, Olsson S |title=Therapeutic equivalence of sulfaisodimidine 2 g twice daily and 1 g four times daily in lower urinary tract infections |journal=Acta medica Scandinavica |volume=211 |issue=5 |pages=361-4 |year=1982 |pmid=7051761 |doi=}}
+* {{cite journal |author=Melander A, Bitzén PO, Olsson S |title=Therapeutic equivalence of sulfaisodimidine 2 g twice daily and 1 g four times daily in lower urinary tract infections |journal=Acta medica Scandinavica |volume=211 |issue=5 |pages=361–4 |year=1982 |pmid=7051761 |doi=10.1111/j.0954-6820.1982.tb01962.x}}
 {{Sulfonamides and trimethoprim}}
 [[Category:Sulfonamide antibiotics]]
+[[Category:Pyrimidines]]
+[[Category:Drug]]
-{{WH}}
-{{WS}}

Clinical data


Routes of administration	Oral
ATC code	J01EB01 (WHO)
Pharmacokinetic data
Metabolism	Minor acetylation
Excretion	Renal, 85%
Identifiers
IUPAC name 4-amino-N-(2,6-dimethylpyrimidin-4-yl) benzenesulfonamide
CAS Number	515-64-0^N
PubChem CID	5343
ChemSpider	5150^Y
UNII	W03L3ODK6E
KEGG	D01526^Y
ChEBI	CHEBI:32166^Y
ChEMBL	ChEMBL485696^Y
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C₁₂H₁₄N₄O₂S
Molar mass	278.331 g/mol
3D model (JSmol)	Interactive image
SMILES O=S(=O)(Nc1nc(nc(c1)C)C)c2ccc(N)cc2
InChI InChI=1S/C12H14N4O2S/c1-8-7-12(15-9(2)14-8)16-19(17,18)11-5-3-10(13)4-6-11/h3-7H,13H2,1-2H3,(H,14,15,16)^Y Key:YZMCKZRAOLZXAZ-UHFFFAOYSA-N^Y
^NY (what is this?) (verify)

Sulfisomidine: Difference between revisions

Latest revision as of 13:06, 15 April 2015

Overview

References

External links

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