Methylphenobarbital: Difference between revisions
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== Overview == | |||
'''Methylphenobarbital''', also known as '''mephobarbital''', (marketed in the US under the brand name '''Mebaral''' by [[Ovation Pharma|Ovation]]) is a drug which is a [[barbiturate]] derivative. | '''Methylphenobarbital''', also known as '''mephobarbital''', (marketed in the US under the brand name '''Mebaral''' by [[Ovation Pharma|Ovation]]) is a drug which is a [[barbiturate]] derivative. | ||
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==References== | ==References== | ||
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* ''The Treatment of Epilepsy 2nd Ed'' by S. D. Shorvon (Editor), David R. Fish (Editor), Emilio Perucca (Editor), W. Edwin Dodson (Editor). Published by Blackwell 2004. ISBN 0-632-06046-8 | * ''The Treatment of Epilepsy 2nd Ed'' by S. D. Shorvon (Editor), David R. Fish (Editor), Emilio Perucca (Editor), W. Edwin Dodson (Editor). Published by Blackwell 2004. ISBN 0-632-06046-8 | ||
{{barbiturates}} | {{barbiturates}} | ||
[[Category:drug]] | |||
[[Category:Barbiturates]] | [[Category:Barbiturates]] | ||
[[Category:Anticonvulsants]] | [[Category:Anticonvulsants]] | ||
Latest revision as of 16:21, 15 April 2015
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| Bioavailability | ? |
| Metabolism | ? |
| Elimination half-life | ? |
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| E number | {{#property:P628}} |
| ECHA InfoCard | {{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value). |
| Chemical and physical data | |
| Formula | C13H14N2O3 |
| Molar mass | 246.3 |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Methylphenobarbital, also known as mephobarbital, (marketed in the US under the brand name Mebaral by Ovation) is a drug which is a barbiturate derivative.
Methylphenobarbital is used as a sedative, anxiolytic and anticonvulsant. It is the N-methylated analogue of phenobarbital, and has similar indications, therapeutic value, and tolerability.
Approval History
- 1935 Mebaral was introduced by Winthrop Pharmaceuticals.
- 2001 Methylphenobarbital discontinued in the UK.
- 2003 Mebaral acquired by Ovation Pharmaceuticals (specialty pharmaceutical company who acquire underpromoted branded pharmaceutical products).
Overdose symptoms
Symptoms of overdose of metharbital include confusion, decrease in or loss of reflexes, somnolence, pyrexia, irritability, hypothermia, poor judgment, shortness of breath or slow/troubled breathing, slow heartbeat, slurred speech, staggering, trouble in sleeping, unusual movements of the eyes, weakness
References
- The Treatment of Epilepsy 2nd Ed by S. D. Shorvon (Editor), David R. Fish (Editor), Emilio Perucca (Editor), W. Edwin Dodson (Editor). Published by Blackwell 2004. ISBN 0-632-06046-8
Categories:
- Pages with script errors
- E number from Wikidata
- ECHA InfoCard ID from Wikidata
- Chemical articles with unknown parameter in Infobox drug
- Articles without EBI source
- Chemical pages without ChemSpiderID
- Articles without KEGG source
- Articles without InChI source
- Articles without UNII source
- Articles containing unverified chemical infoboxes
- Drug
- Barbiturates
- Anticonvulsants
- Anxiolytics