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| {{drugbox
| | #REDIRECT[[Propantheline bromide]] |
| |IUPAC_name=methyl-bis(1-methylethyl)- [2-(9H-xanthen-9-ylcarbonyloxy)ethyl]ammonium
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| |image=Propantheline.svg
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| |CAS_number=298-50-0
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| |ATC_prefix=A03
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| |ATC_suffix=AB05
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| |ATC_supplemental=
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| |PubChem=4934
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| |DrugBank=APRD00177
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| |C=23|H=30|N=1|O=3
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| |molecular_weight=368.489 g/mol
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| |bioavailability=
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| |protein_bound=
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| |metabolism=
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| |elimination_half-life=
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| |excretion=
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| |pregnancy_AU=<!-- A / B1 / B2 / B3 / C / D / X -->
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| |pregnancy_US=<!-- A / B / C / D / X -->
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| |pregnancy_category=
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| |legal_AU=<!-- Unscheduled / S2 / S4 / S8 -->
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| |legal_UK=<!-- GSL / P / POM / CD -->
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| |legal_US=<!-- OTC / Rx-only -->
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| |legal_status=
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| |routes_of_administration=
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| }}
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| '''Propantheline''' (usually as '''propantheline [[bromide]]''') is a type of medical agent called an [[antimuscarinic]]. It works by blocking the action of the chemical messenger substance [[acetylcholine]] on so-called [[muscarinic receptor]]s present in various [[smooth muscle|smooth muscular]] tissues.
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| Normally, the binding of acetylcholine induces involuntary smooth muscular contractions. By relaxing the gut muscle, propantheline can relieve pain in conditions caused by [[spasm]] of the muscle in the gut. Relaxing the smooth muscle in the [[Urinary bladder|bladder]] prevents the involuntary spasms that can allow leakage of [[urine]] from the bladder in the condition known as [[enuresis]] (involuntary urination in adults). Propantheline can also be used to treat excessive [[sweating]] because acetylcholine block also reduces secretions such as sweat and [[tears]].
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| Side effects include; tachycardia, constipation, hyper-sensitivity to light, a dry mouth, and urinary retention.
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| [[Category:Anticholinergics]]
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| [[Category:Quaternary ammonium compounds]]
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| {{pharma-stub}}
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| {{Drugs for functional gastrointestinal disorders}}
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