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| {{DrugProjectFormSinglePage | | {{Details0|Diphenhydramine (oral)}} |
| |authorTag={{AJ}}
| | {{Details0|Diphenhydramine (Injection)}} |
| |genericName=Diphenhydramine hydrochloride | | {{Details0|Diphenhydramine (topical)}} |
| |aOrAn=a
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| |drugClass=Analgesic , Antihistamine
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| |indicationType=treatment
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| |indication=temporarily relieves symptoms of the common cold like
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| runny nose, sneezing, itchy watery eyes, itchy nose or throat
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| |adverseReactions=[[Xerostomia]], [[dizziness]], [[dyskinesia]], [[sedatation]], [[somnolence]]
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| dryness of nasal mucosa, [[pharyngeal dryness]], thick sputum.
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| |blackBoxWarningTitle=<span style="color:#FF0000;">ConditionName: </span>
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| |blackBoxWarningBody=<i><span style="color:#FF0000;">ConditionName: </span></i>
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| * Content
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| <!--Adult Indications and Dosage-->
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| <!--FDA-Labeled Indications and Dosage (Adult)-->
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| |fdaLIADAdult=* Temporarily relieves these symptoms due to hay fever or other upper respiratory allergies:
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| :* Runny nose
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| :* Sneezing
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| :* Itchy, watery eyes
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| :* Itchy nose or throat
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| * Temporarily relieves these symptoms of the common cold:
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| :* Runny nose
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| :* Sneezing
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| * Dosing Information
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| :* Take every 4 to 6 hours, not more than 6 doses in 24 hours
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| |offLabelAdultGuideSupport=* Chemotherapy-induced nausea and vomiting.
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| * Extrapyramidal disease - Medication-induced movement disorder.
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| * Hyperemesis gravidarum.
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| * Local anesthesia
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| |offLabelAdultNoGuideSupport=There is limited information regarding <i>Off-Label Non–Guideline-Supported Use</i> of Diphenhydramine in adult patients.
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| <!--Pediatric Indications and Dosage-->
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| <!--FDA-Labeled Indications and Dosage (Pediatric)-->
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| |fdaLIADPed======Condition1=====
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| * Dosing Information
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| :* Dosage
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| =====Condition2=====
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| There is limited information regarding <i>FDA-Labeled Use</i> of {{PAGENAME}} in pediatric patients.
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| <!--Off-Label Use and Dosage (Pediatric)-->
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| <!--Guideline-Supported Use (Pediatric)-->
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| |offLabelPedGuideSupport=There is limited information regarding <i>Off-Label Guideline-Supported Use</i> of Diphenhydramine in pediatric patients. | |
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| <!--Non–Guideline-Supported Use (Pediatric)-->
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| |offLabelPedNoGuideSupport=There is limited information regarding <i>Off-Label Non–Guideline-Supported Use</i> of Diphenhydramine in pediatric patients.
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| <!--Contraindications-->
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| |contraindications=* Diphenhydramine is contraindicated in persons with known hypersensitivity.
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| |warnings=* Do not use with any other product containing diphenhydramine, even one used on skin
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| * To make a child sleepy
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| * Ask a doctor before use if you have glaucoma
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| * Trouble urinating due to an enlarged prostate gland
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| * A breathing problem such as emphysema or chronic bronchitis
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| * Ask a doctor or pharmacist before use if you are taking sedatives or tranquilizers
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| When using this product
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| marked drowsiness may occur
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| avoid alcoholic drinks
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| excitability may occur, especially in children
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| alcohol, sedatives and tranquilizers may increase drowsiness
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| be careful when driving a motor vehicle or operating machinery
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| If pregnant or breast-feeding,
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| ask a health professional before use.
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| Keep out of reach of children.
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| In case of overdose, get medical help or contact a Poison Control Center right away.
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| |clinicalTrials======Digestive=====
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| * Xerostomia
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| =====Neurologic=====
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| * Sedation
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| * Dizziness
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| * Dyskinesia
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| * Somnolence
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| =====Respiratory=====
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| * Dryness of nasal mucosa
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| * Pharyngeal dryness
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| * Thick sputum
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| * Bronchial dryness
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| =====Miscellaneous====
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| * Anaphylaxis reaction
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| <!--Postmarketing Experience-->
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| |postmarketing=There is limited information regarding <i>Postmarketing Experience</i> of Diphenhydramine in the drug label.
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| =====Body as a Whole=====
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| =====Cardiovascular=====
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| =====Digestive=====
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| =====Endocrine=====
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| =====Hematologic and Lymphatic=====
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| =====Metabolic and Nutritional=====
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| =====Musculoskeletal=====
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| =====Neurologic=====
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| =====Respiratory=====
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| =====Skin and Hypersensitivy Reactions=====
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| =====Special Senses=====
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| =====Urogenital=====
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| =====Miscellaneous=====
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| <!--Drug Interactions-->
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| |drugInteractions=There is limited information regarding <i>drug interactions</i> of Diphenhydramine in the drug label.
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| |FDAPregCat=B
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| |useInPregnancyFDA=* '''Pregnancy Category'''
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| |useInPregnancyAUS=* '''Australian Drug Evaluation Committee (ADEC) Pregnancy Category'''
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| There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of Diphenhydramine in women who are pregnant.
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| |useInLaborDelivery=There is no FDA guidance on use of Diphenhydramine during labor and delivery.
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| |useInNursing=There is no FDA guidance on the use of Diphenhydramine with respect to nursing mothers.
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| |useInPed=* Keep out of reach of children.
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| * In case of overdose, get medical help or contact a Poison Control Center right away.
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| |useInGeri=There is no FDA guidance on the use of Diphenhydramine with respect to geriatric patients.
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| |useInGender=There is no FDA guidance on the use of Diphenhydramine with respect to specific gender populations.
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| |useInRace=There is no FDA guidance on the use of Diphenhydramine with respect to specific racial populations.
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| |useInRenalImpair=There is no FDA guidance on the use of Diphenhydramine in patients with renal impairment.
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| |useInHepaticImpair=There is no FDA guidance on the use of Diphenhydramine in patients with hepatic impairment.
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| |useInReproPotential=There is no FDA guidance on the use of Diphenhydramine in women of reproductive potentials and males.
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| |useInImmunocomp=There is no FDA guidance one the use of Diphenhydramine in patients who are immunocompromised.
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| <!--Administration and Monitoring-->
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| |administration=* Intramuscular
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| * Intravenous
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| * Oral
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| |monitoring=There is limited information regarding <i>Monitoring</i> of Diphenhydramine in the drug label.
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| <!--IV Compatibility-->
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| |IVCompat=There is limited information regarding <i>IV Compatibility</i> of Diphenhydramine in the drug label.
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| <!--Overdosage-->
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| |overdose=There is limited information regarding <i>Chronic Overdose</i> of Diphenhydramine in the drug label.
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| <!--Pharmacology-->
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| <!--Drug box 2-->
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| |drugBox=<!--Mechanism of Action-->
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| |mechAction=*
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| <!--Structure-->
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| |structure=*
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| : [[File:{{PAGENAME}}01.png|thumb|none|600px|This image is provided by the National Library of Medicine.]]
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| <!--Pharmacodynamics-->
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| |PD=There is limited information regarding <i>Pharmacodynamics</i> of {{PAGENAME}} in the drug label.
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| <!--Pharmacokinetics-->
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| |PK=There is limited information regarding <i>Pharmacokinetics</i> of {{PAGENAME}} in the drug label.
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| <!--Nonclinical Toxicology-->
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| |nonClinToxic=There is limited information regarding <i>Nonclinical Toxicology</i> of Diphenhydramine in the drug label. | |
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| <!--Clinical Studies-->
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| |clinicalStudies=There is limited information regarding <i>Clinical Studies</i> of Diphenhydramine in the drug label.
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| <!--How Supplied-->
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| |howSupplied=*
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| <!--Patient Counseling Information-->
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| |storage=store at 20°-25°C
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| |fdaPatientInfo=* Marked drowsiness may occur
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| * Avoid alcoholic drinks
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| * Excitability may occur, especially in children
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| * Alcohol, sedatives and tranquilizers may increase drowsiness
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| * Be careful when driving a motor vehicle or operating machinery
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| |alcohol=* Avoid alcoholic drinks.
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| * Alcohol, sedatives and tranquilizers may increase drowsiness.
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| |brandNames=* Benadryl®
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| * Benylin Decongestant Cough®
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| * Diphenhist
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| * Diphenyl®
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| * Genahist®
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| * Geridryl®
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| * Nytol Quickcaps®
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| * Nytol Quickgels®
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| |lookAlike=* Benadryl® - benazepril®
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| * diphenhydrAMINE® - dimenhyDRINATE®
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| |drugShortage=
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| }}
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| {{PillImage
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| |fileName=No image.jpg
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| }}
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| {{LabelImage
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| |fileName={{PAGENAME}}11.png
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| }} | |
| {{LabelImage
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| |fileName={{PAGENAME}}11.png
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| }}
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| <!--Pill Image-->
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| <!--Label Display Image-->
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| <!--Category-->
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| [[Category:Drug]]
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