Bronchospasm pathophysiology: Difference between revisions
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==Pathophysiology== | |||
Bronchospasm is caused by the release ([[degranulation]]) of substances from [[mast cells]] or [[basophil]]s under the influence of [[anaphylatoxin]]s. The overactivity of the bronchioles' muscle is a result of exposure to a stimulus which under normal circumstances would cause little or no response. The resulting constriction and inflammation causes a narrowing of the airways and an increase in [[mucus]] production; this reduces the amount of [[oxygen]] that is available to the individual causing breathlessness, coughing and [[hypoxia (medical)|hypoxia]]. | Bronchospasm is caused by the release ([[degranulation]]) of substances from [[mast cells]] or [[basophil]]s under the influence of [[anaphylatoxin]]s. The overactivity of the bronchioles' muscle is a result of exposure to a stimulus which under normal circumstances would cause little or no response. The resulting constriction and inflammation causes a narrowing of the airways and an increase in [[mucus]] production; this reduces the amount of [[oxygen]] that is available to the individual causing breathlessness, coughing and [[hypoxia (medical)|hypoxia]]. | ||
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{{Reflist|2}} | {{Reflist|2}} | ||
[[Category:Needs overview]] | |||
[[Category:Pulmonology]] | [[Category:Pulmonology]] | ||
[[Category:Emergency medicine]] | [[Category:Emergency medicine]] | ||
[[Category:Intensive care medicine]] | [[Category:Intensive care medicine]] | ||
{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} | ||
Latest revision as of 13:20, 2 June 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Pathophysiology
Bronchospasm is caused by the release (degranulation) of substances from mast cells or basophils under the influence of anaphylatoxins. The overactivity of the bronchioles' muscle is a result of exposure to a stimulus which under normal circumstances would cause little or no response. The resulting constriction and inflammation causes a narrowing of the airways and an increase in mucus production; this reduces the amount of oxygen that is available to the individual causing breathlessness, coughing and hypoxia.
