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==Overview==
==Pathophysiology==
There are three [[histological]] variants of [[chordoma]]: classical, chondroid and dedifferentiated. The  histological appearance of classical chordoma is of a lobulated [[tumor]] composed of groups of cells separated by fibrous septa. The cells have small round nuclei and abundant vacuolated [[cytoplasm]], sometimes described as physaliferous (resembling a spider's web). Chondroid chordomas histologically show features of both [[chordoma]] and [[chondrosarcoma]].
==References==
==References==
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Latest revision as of 14:52, 18 August 2015

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Chordoma Microchapters

Home

Patient Information

Overview

Historical Perspective

Pathophysiology

Epidemiology and Demographics

Risk Factors

Screening

Causes

Differentiating Chordoma from other Diseases

Natural History, Complications and Prognosis

Diagnosis

Staging

History and Symptoms

Physical Examination

Laboratory Findings

Chest X Ray

CT

MRI

Echocardiography or Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Chordoma pathophysiology On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Chordoma pathophysiology

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Chordoma pathophysiology

CDC on Chordoma pathophysiology

Chordoma pathophysiology in the news

Blogs on Chordoma pathophysiology

Directions to Hospitals Treating Chordoma

Risk calculators and risk factors for Chordoma pathophysiology

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Pathophysiology

There are three histological variants of chordoma: classical, chondroid and dedifferentiated. The histological appearance of classical chordoma is of a lobulated tumor composed of groups of cells separated by fibrous septa. The cells have small round nuclei and abundant vacuolated cytoplasm, sometimes described as physaliferous (resembling a spider's web). Chondroid chordomas histologically show features of both chordoma and chondrosarcoma.

References


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