Post-chemotherapy cognitive impairment medical therapy: Difference between revisions
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{{Post-chemotherapy cognitive impairment}} | {{Post-chemotherapy cognitive impairment}} | ||
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==Treatment== | |||
Hypothesized treatment options include the use of [[antioxidant]]s, [[cognitive behavior therapy]], [[erythropoietin]] and stimulant drugs such as [[methylphenidate]], though as the mechanism of PCCI is not well understood the potential treatment options are equally theoretical. | |||
[[Modafinil]], approved for [[narcolepsy]], has been used [[off-label]] in trials with people with symptoms of PCCI. Modafinil is a wakefulness-promoting agent that can improve alertness and concentration, and studies have shown it to be effective at least among women treated for breast cancer.<ref>[http://content.hamptonroads.com/story.cfm?story=133730&ran=181335 Doctors are finding it harder to deny "Chemobrain"] The Virginian-Pilot October 2, 2007</ref><ref>[http://psychnews.psychiatryonline.org/newsarticle.aspx?articleid=111136 Modafinil Relieves Cognitive Chemotherapy Side Effects] Psychiatric News, Stephanie Whyche, August 3, 2007 Volume 42 Number 15, page 31</ref> | |||
While estrogen hormone supplementation may reverse the symptoms of PCCI in women treated for breast cancer, this carries health risks, including possibly promoting the proliferation of estrogen-responsive breast cancer cells. | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
Latest revision as of 16:04, 18 August 2015
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Post-chemotherapy cognitive impairment Microchapters |
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Differentiating Post-chemotherapy cognitive impairment from other Diseases |
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Post-chemotherapy cognitive impairment medical therapy On the Web |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Treatment
Hypothesized treatment options include the use of antioxidants, cognitive behavior therapy, erythropoietin and stimulant drugs such as methylphenidate, though as the mechanism of PCCI is not well understood the potential treatment options are equally theoretical.
Modafinil, approved for narcolepsy, has been used off-label in trials with people with symptoms of PCCI. Modafinil is a wakefulness-promoting agent that can improve alertness and concentration, and studies have shown it to be effective at least among women treated for breast cancer.[1][2]
While estrogen hormone supplementation may reverse the symptoms of PCCI in women treated for breast cancer, this carries health risks, including possibly promoting the proliferation of estrogen-responsive breast cancer cells.
References
- ↑ Doctors are finding it harder to deny "Chemobrain" The Virginian-Pilot October 2, 2007
- ↑ Modafinil Relieves Cognitive Chemotherapy Side Effects Psychiatric News, Stephanie Whyche, August 3, 2007 Volume 42 Number 15, page 31