Aglepristone: Difference between revisions

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==Overview==
 
'''Aglepristone''' ([[International Nonproprietary Name|INN]]) (brand name '''Alizine'''; former code names '''RU-46534''', '''RU-534''') is a [[steroid]]al [[antiprogestin]] ([[progesterone receptor]] [[silent antagonist|full antagonist]]) related to [[mifepristone]] which is marketed by [[Virbac]] in several [[Europe]]an countries for use in [[veterinary medicine]].<ref name="BonaguraTwedt2013">{{cite book|author1=John D. Bonagura|author2=David C. Twedt|title=Kirk's Current Veterinary Therapy XV|url=http://books.google.com/books?id=KlJKAgAAQBAJ&pg=PT3009|date=1 December 2013|publisher=Elsevier Health Sciences|isbn=978-0-323-22762-9|pages=3009–}}</ref><ref name="Squires2010">{{cite book|author=E. James Squires|title=Applied Animal Endocrinology|url=http://books.google.com/books?id=Q-rP6Fc9-N4C&pg=PA207|year=2010|publisher=CABI|isbn=978-1-84593-755-3|pages=207–}}</ref><ref name="Papich2010">{{cite book|author=Mark G. Papich|title=Saunders Handbook of Veterinary Drugs: Small and Large Animal|url=http://books.google.com/books?id=PeJTVfaAiYAC&pg=PT120|date=3 November 2010|publisher=Elsevier Health Sciences|isbn=1-4377-0192-2|pages=120–}}</ref> It is specifically used as an [[abortifacient]] in [[pregnant]].<ref name="BonaguraTwedt2013" /><ref name="Papich2010" /><ref name="Concannon2001">{{cite book|author=Patrick W. Concannon|title=Advances in reproduction in dogs, cats and exotic carnivores: proceedings of the fourth International Symposium on Canine and Feline Reproduction, Oslo, Norway, 29 June-1 July 2000|url=http://books.google.com/books?id=q-E4AQAAIAAJ|year=2001|publisher=Journal of Reproduction and Fertility|isbn=978-0-906545-37-9}}</ref> Aglepristone, similarly to mifepristone, also possesses some [[antiglucocorticoid]] activity.{{Citation needed|date=January 2015}}
'''Aglepristone''' ([[International Nonproprietary Name|INN]]) (brand name '''Alizine'''; former code names '''RU-46534''', '''RU-534''') is a [[steroid]]al [[antiprogestin]] ([[progesterone receptor]] [[silent antagonist|full antagonist]]) related to [[mifepristone]] which is marketed by [[Virbac]] in several [[Europe]]an countries for use in [[veterinary medicine]].<ref name="BonaguraTwedt2013">{{cite book|author1=John D. Bonagura|author2=David C. Twedt|title=Kirk's Current Veterinary Therapy XV|url=http://books.google.com/books?id=KlJKAgAAQBAJ&pg=PT3009|date=1 December 2013|publisher=Elsevier Health Sciences|isbn=978-0-323-22762-9|pages=3009–}}</ref><ref name="Squires2010">{{cite book|author=E. James Squires|title=Applied Animal Endocrinology|url=http://books.google.com/books?id=Q-rP6Fc9-N4C&pg=PA207|year=2010|publisher=CABI|isbn=978-1-84593-755-3|pages=207–}}</ref><ref name="Papich2010">{{cite book|author=Mark G. Papich|title=Saunders Handbook of Veterinary Drugs: Small and Large Animal|url=http://books.google.com/books?id=PeJTVfaAiYAC&pg=PT120|date=3 November 2010|publisher=Elsevier Health Sciences|isbn=1-4377-0192-2|pages=120–}}</ref> It is specifically used as an [[abortifacient]] in [[pregnant]].<ref name="BonaguraTwedt2013" /><ref name="Papich2010" /><ref name="Concannon2001">{{cite book|author=Patrick W. Concannon|title=Advances in reproduction in dogs, cats and exotic carnivores: proceedings of the fourth International Symposium on Canine and Feline Reproduction, Oslo, Norway, 29 June-1 July 2000|url=http://books.google.com/books?id=q-E4AQAAIAAJ|year=2001|publisher=Journal of Reproduction and Fertility|isbn=978-0-906545-37-9}}</ref> Aglepristone, similarly to mifepristone, also possesses some [[antiglucocorticoid]] activity.{{Citation needed|date=January 2015}}


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{{Antiprogestogens}}
{{Glucocorticoidics}}
{{Progestogenics}}


[[Category:Abortifacients]]
[[Category:Abortifacients]]
[[Category:Antiglucocorticoids]]
[[Category:Antiglucocorticoids]]
[[Category:Antiprogestogens]]
[[Category:Drug]]
[[Category:Steroids]]
[[Category:Steroids]]
[[Category:Veterinary drugs]]
{{genito-urinary-drug-stub}}
{{steroid-stub}}

Latest revision as of 17:16, 18 August 2015

Aglepristone
Clinical data
ATC code
Identifiers
CAS Number
PubChem CID
ChemSpider
E number{{#property:P628}}
ECHA InfoCard{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
FormulaC29H37NO2
Molar mass431.610 g/mol
3D model (JSmol)

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Aglepristone (INN) (brand name Alizine; former code names RU-46534, RU-534) is a steroidal antiprogestin (progesterone receptor full antagonist) related to mifepristone which is marketed by Virbac in several European countries for use in veterinary medicine.[1][2][3] It is specifically used as an abortifacient in pregnant.[1][3][4] Aglepristone, similarly to mifepristone, also possesses some antiglucocorticoid activity.[citation needed]

References

  1. 1.0 1.1 John D. Bonagura; David C. Twedt (1 December 2013). Kirk's Current Veterinary Therapy XV. Elsevier Health Sciences. pp. 3009–. ISBN 978-0-323-22762-9.
  2. E. James Squires (2010). Applied Animal Endocrinology. CABI. pp. 207–. ISBN 978-1-84593-755-3.
  3. 3.0 3.1 Mark G. Papich (3 November 2010). Saunders Handbook of Veterinary Drugs: Small and Large Animal. Elsevier Health Sciences. pp. 120–. ISBN 1-4377-0192-2.
  4. Patrick W. Concannon (2001). Advances in reproduction in dogs, cats and exotic carnivores: proceedings of the fourth International Symposium on Canine and Feline Reproduction, Oslo, Norway, 29 June-1 July 2000. Journal of Reproduction and Fertility. ISBN 978-0-906545-37-9.