Biapenem: Difference between revisions

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Biapenem
Clinical data
AHFS/Drugs.com	International Drug Names
Routes of; administration	IV
ATC code	J01DH05 (WHO) ;
Legal status
Legal status	In general: ℞ (Prescription only);
Identifiers
	IUPAC name (4R,5S,6S)-3-(6,7-dihydro-5H- pyrazolo[1,2-a][1,2,4]triazol-8- ium-6-ylsulfanyl)- 6-(1-hydroxyethyl)- 4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2- ene-2-carboxylate;
CAS Number	120410-24-4 ;
PubChem CID	71339;
ChemSpider	64442 ;
UNII	YR5U3L9ZH1;
ChEBI	CHEBI:3089 ;
ChEMBL	ChEMBL285347 ;
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C15H18N4O4S
Molar mass	350.39 g/mol
3D model (JSmol)	Interactive image;
	SMILES CC1C2C(C(=O)N2C(=C1SC3CN4C=NC=[N+]4C3)C(=O)[O-])C(C)O;
	InChI InChI=1S/C15H18N4O4S/c1-7-11-10(8(2)20)14(21)19(11)12(15(22)23)13(7)24-9-3-17-5-16-6-18(17)4-9/h5-11,20H,3-4H2,1-2H3/t7-,8-,10-,11-/m1/s1 ; Key:MRMBZHPJVKCOMA-YJFSRANCSA-N ;
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Latest revision as of 18:08, 18 August 2015

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Biapenem (INN) is a carbapenem antibiotic. It has in vitro activity against anaerobes.^[1]

Approved in Japan in 2001.

@@ Line 55: / Line 55: @@
 | StdInChIKey = MRMBZHPJVKCOMA-YJFSRANCSA-N
 }}
+              __NOTOC__
+{{SI}}
+{{CMG}}
+==Overview==
 '''Biapenem''' ([[International Nonproprietary Name|INN]]) is a [[carbapenem]] antibiotic. It has in vitro activity against anaerobes.<ref name="pmid8031067">{{cite journal |author=Aldridge KE, Morice N, Schiro DD |title=In vitro activity of biapenem (L-627), a new carbapenem, against anaerobes |journal=Antimicrob. Agents Chemother. |volume=38 |issue=4 |pages=889–93 |date=April 1994 |pmid=8031067 |pmc=284564 |doi= 10.1128/aac.38.4.889|url=http://aac.asm.org/cgi/pmidlookup?view=long&pmid=8031067}}</ref>
@@ Line 69: / Line 74: @@
 [[Category:Carbapenem antibiotics]]
+[[Category:Drug]]
-{{antibiotic-stub}}

v t e Antibacterials: cell wall disruption (J01C-J01D)
Internal to membrane/ (inhibit peptidoglycan subunit synthesis and transport)	Template:Navbox subgroup
Glycopeptide/ (inhibit PG chain elongation)	Vancomycin # (Oritavancin, Telavancin) · Teicoplanin (Dalbavancin) · Ramoplanin
Beta-lactams/ (inhibit cross-links with PBP)	Template:Navbox subgroup
Other	Template:Navbox subgroup
# = WHO-EM

Clinical data

AHFS/Drugs.com	International Drug Names
Routes of administration	IV
ATC code	J01DH05 (WHO)
Legal status
Legal status	In general: ℞ (Prescription only)
Identifiers
IUPAC name (4R,5S,6S)-3-(6,7-dihydro-5H- pyrazolo[1,2-a][1,2,4]triazol-8- ium-6-ylsulfanyl)- 6-(1-hydroxyethyl)- 4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2- ene-2-carboxylate
CAS Number	120410-24-4^Y
PubChem CID	71339
ChemSpider	64442^Y
UNII	YR5U3L9ZH1
ChEBI	CHEBI:3089^Y
ChEMBL	ChEMBL285347^Y
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C₁₅H₁₈N₄O₄S
Molar mass	350.39 g/mol
3D model (JSmol)	Interactive image
SMILES CC1C2C(C(=O)N2C(=C1SC3CN4C=NC=[N+]4C3)C(=O)[O-])C(C)O
InChI InChI=1S/C15H18N4O4S/c1-7-11-10(8(2)20)14(21)19(11)12(15(22)23)13(7)24-9-3-17-5-16-6-18(17)4-9/h5-11,20H,3-4H2,1-2H3/t7-,8-,10-,11-/m1/s1^Y Key:MRMBZHPJVKCOMA-YJFSRANCSA-N^Y
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