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Created page with "__NOTOC__ {{Drugbox | Verifiedfields = changed | verifiedrevid = 459980346 | IUPAC_name = 2,2'-sulfanediylbis(4,6-dichlorophenol) | image = Bithionol.png <!--Clinical data-->..."
 
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__NOTOC__
{{Drugbox
{{Drugbox
| Verifiedfields = changed
| Verifiedfields = changed
| Watchedfields = changed
| verifiedrevid = 459980346
| verifiedrevid = 459980346
| IUPAC_name = 2,2'-sulfanediylbis(4,6-dichlorophenol)
| IUPAC_name = 2,2'-sulfanediylbis(4,6-dichlorophenol)
| image = Bithionol.png
| image = Bithionol.png
| image2 = Bithionol_molecule_ball.png
| alt2 = Ball-and-stick model of the bithionol molecule
| width2 = 240


<!--Clinical data-->
<!--Clinical data-->
| tradename =  
| tradename =
| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X -->
| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X -->
| pregnancy_US = <!-- A / B            / C / D / X -->
| pregnancy_US = <!-- A / B            / C / D / X -->
| pregnancy_category =  
| pregnancy_category =
| legal_AU = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled-->
| legal_AU = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled-->
| legal_CA = <!-- Schedule I, II, III, IV, V, VI, VII, VIII -->
| legal_CA = <!-- Schedule I, II, III, IV, V, VI, VII, VIII -->
| legal_UK = <!-- GSL, P, POM, CD, or Class A, B, C -->
| legal_UK = <!-- GSL, P, POM, CD, or Class A, B, C -->
| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V -->
| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V -->
| legal_status =  
| legal_status =
| routes_of_administration =  
| routes_of_administration =


<!--Pharmacokinetic data-->
<!--Pharmacokinetic data-->
| bioavailability =  
| bioavailability =
| protein_bound =  
| protein_bound =
| metabolism =  
| metabolism =
| elimination_half-life =  
| elimination_half-life =
| excretion =  
| excretion =


<!--Identifiers-->
<!--Identifiers-->
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|  ChEBI_Ref = {{ebicite|correct|EBI}}
|  ChEBI_Ref = {{ebicite|correct|EBI}}
| ChEBI = 3131
| ChEBI = 3131
| SMILES = Clc2cc(Cl)cc(Sc1cc(Cl)cc(Cl)c1O)c2O
| smiles = Clc2cc(Cl)cc(Sc1cc(Cl)cc(Cl)c1O)c2O
|  InChI = 1/C12H6Cl4O2S/c13-5-1-7(15)11(17)9(3-5)19-10-4-6(14)2-8(16)12(10)18/h1-4,17-18H
|  InChI = 1/C12H6Cl4O2S/c13-5-1-7(15)11(17)9(3-5)19-10-4-6(14)2-8(16)12(10)18/h1-4,17-18H
|  InChIKey = JFIOVJDNOJYLKP-UHFFFAOYAO
|  InChIKey = JFIOVJDNOJYLKP-UHFFFAOYAO
Line 52: Line 55:


<!--Chemical data-->
<!--Chemical data-->
| C=12 | H=6 | Cl=4 | O=2 | S=1
| C=12 | H=6 | Cl=4 | O=2 | S=1  
| molecular_weight = 356.05 g/mol
| molecular_weight = 356.05 g/mol
| synonyms = 2,4-dichloro- 6-(3,5-dichloro- 2-hydroxyphenyl)sulfanylphenol
| synonyms = 2,4-dichloro- 6-(3,5-dichloro- 2-hydroxyphenyl)sulfanylphenol
}}
}}
 
              __NOTOC__
{{SI}}
{{SI}}
{{CMG}}
{{CMG}}
==Overview==
==Overview==  
 
 
'''Bithionol''' is an [[anthelmintic]] used to treat "[[Anoplocephala perfoliata]]" (tapeworms) in horses<ref>[http://www.ncbi.nlm.nih.gov/pubmed/19498288], Sanada Y, Senba H, Mochizuki R, et al. Evaluation of marked rise in fecal egg output after bithionol administration to horse and its application as a diagnostic marker for equine Anoplocephala perfoliata infection. J. Vet. Med. Sci. May 2009;71(5):617-620.</ref> and ''[[Fasciola hepatica]]'' (liver flukes).
'''Bithionol''' is an [[anthelmintic]] used to treat ''[[Anoplocephala perfoliata]]'' (tapeworms) in horses<ref>{{ cite journal | author = Sanada Y, Senba H, Mochizuki R, Arakaki H, Gotoh T, Fukumoto S, Nagahata H | title = Evaluation of Marked Rise in Fecal Egg Output after Bithionol Administration to Horse and its Application as a Diagnostic Marker for Equine ''Anoplocephala perfoliata'' Infection | journal = Journal of Veterinary Medical Science | year = 2009 | volume = 71 | issue = 5 | pages = 617–620 | pmid = 19498288 | doi = 10.1292/jvms.71.617 | url = https://www.jstage.jst.go.jp/article/jvms/71/5/71_5_617/_pdf | format = pdf }}</ref> and ''[[Fasciola hepatica]]'' (liver flukes).


==References==
==References==
{{reflist}}
{{reflist|2}}


{{Anthelmintics}}
{{Anthelmintics}}
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[[Category:Phenols]]
[[Category:Phenols]]
[[Category:Thioethers]]
[[Category:Thioethers]]
 
[[Category:Drug]]
 
{{antiinfective-drug-stub}}
{{dermatologic-drug-stub}}

Latest revision as of 18:11, 18 August 2015

Bithionol
Ball-and-stick model of the bithionol molecule
Clinical data
Synonyms2,4-dichloro- 6-(3,5-dichloro- 2-hydroxyphenyl)sulfanylphenol
ATC code
Identifiers
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
ChEBI
ChEMBL
E number{{#property:P628}}
ECHA InfoCard{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
FormulaC12H6Cl4O2S
Molar mass356.05 g/mol
3D model (JSmol)
 ☒N☑Y (what is this?)  (verify)

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Bithionol is an anthelmintic used to treat Anoplocephala perfoliata (tapeworms) in horses[1] and Fasciola hepatica (liver flukes).

References

  1. ↑ Sanada Y, Senba H, Mochizuki R, Arakaki H, Gotoh T, Fukumoto S, Nagahata H (2009). "Evaluation of Marked Rise in Fecal Egg Output after Bithionol Administration to Horse and its Application as a Diagnostic Marker for Equine Anoplocephala perfoliata Infection" (pdf). Journal of Veterinary Medical Science. 71 (5): 617–620. doi:10.1292/jvms.71.617. PMID 19498288.

Template:Anthelmintics

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