Cefpirome

Cefpirome

Clinical data
AHFS/Drugs.com	International Drug Names
ATC code	J01DE02 (WHO)
Identifiers
IUPAC name 1-{[(6R,7R)-7-[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-2-carboxylato-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}-5H,6H,7H-cyclopenta[b]pyridin-1-ium
CAS Number	84957-29-9 Y
PubChem CID	6917674
ChemSpider	23089536 N
UNII	S72Q2F09HY
KEGG	D07649 Y
ChEMBL	ChEMBL2106076 N
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}
Chemical and physical data
Formula	C22H22N6O5S2
Molar mass	514.58 g/mol
3D model (JSmol)	Interactive image
SMILES CON=C(c1csc(n1)N)C(=O)NC2C3N(C2=O)C(=C(CS3)C[n+]4cccc5c4CCC5)C(=O)[O-]
InChI InChI=1S/C22H22N6O5S2/c1-33-26-15(13-10-35-22(23)24-13)18(29)25-16-19(30)28-17(21(31)32)12(9-34-20(16)28)8-27-7-3-5-11-4-2-6-14(11)27/h3,5,7,10,16,20H,2,4,6,8-9H2,1H3,(H3-,23,24,25,29,31,32)/b26-15-/t16-,20+/m1/s1 N Key:DKOQGJHPHLTOJR-XECLGWKCSA-N N
NY (what is this?)  (verify)

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Evidence Based Medicine
Cochrane Collaboration on Cefpirome Bandolier on Cefpirome TRIP on Cefpirome
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Cefpirome is a fourth-generation cephalosporin. Trade names include Cefrom, Keiten, Broact, and Cefir. Cefpirome is considered highly active against Gram-negative bacteria, including Pseudomonas aeruginosa, and Gram-positive bacteria.

Spectrum of bacterial susceptibility and resistance

Bacteroides fragilis, enterococci, Pseudomonas spp. and staphylococci are resistant to cefpirome sulfate, and some Haemophilus spp. and pneumococci have developed resistance to it to varying degrees.