Estrone and sus scrofa: Difference between revisions
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| IUPAC_name = (8R,9S,13S,14S)-3-hydroxy-13-methyl- 6,7,8,9,11,12,13,14,15,16- decahydrocyclopenta[a]phenanthren- 17- one | | IUPAC_name = (8R,9S,13S,14S)-3-hydroxy-13-methyl- 6,7,8,9,11,12,13,14,15,16- decahydrocyclopenta[a]phenanthren- 17- one | ||
<!--Clinical data--> | <!--Clinical data--> | ||
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|storage=* Store in cool, dry place. | |storage=* Store in cool, dry place. | ||
|packLabel=[[File:DailyMed - ESTROGEN- estrone and sus scrofa ovary liquid .png|thumb|none|400px|This image is provided by the National Library of Medicine.]] | |packLabel=[[File:File:DailyMed - ESTROGEN- estrone and sus scrofa ovary liquid .png|thumb|none|400px|This image is provided by the National Library of Medicine.]] | ||
|fdaPatientInfo=* 10 drops orally, 3 times a day. Consult a physician for use in children under 12 years of age. | |fdaPatientInfo=* 10 drops orally, 3 times a day. Consult a physician for use in children under 12 years of age. | ||
|alcohol=Alcohol-Estrone and sus scrofa interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication. | |alcohol=Alcohol-Estrone and sus scrofa interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication. |
Latest revision as of 20:36, 18 August 2015
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]
Disclaimer
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NOTE: Most over the counter (OTC) are not reviewed and approved by the FDA. However, they may be marketed if they comply with applicable regulations and policies. FDA has not evaluated whether this product complies.
Overview
Estrone and sus scrofa is a hormone analog that is FDA approved for the treatment of for temporary relief of breast tenderness, hot flashes, irregular periods, mood swings, anxiety, headaches, and nervousness. Common adverse reactions include hypersensitivity.
Adult Indications and Dosage
FDA-Labeled Indications and Dosage (Adult)
- For temporary relief of breast tenderness, hot flashes, irregular periods, mood swings, anxiety, headaches, and nervousness.
- 10 drops orally, 3 times a day.
Off-Label Use and Dosage (Adult)
Guideline-Supported Use
There is limited information regarding Off-Label Guideline-Supported Use of Estrone and sus scrofa in adult patients.
Non–Guideline-Supported Use
There is limited information regarding Off-Label Non–Guideline-Supported Use of Estrone and sus scrofa in adult patients.
Pediatric Indications and Dosage
FDA-Labeled Indications and Dosage (Pediatric)
There is limited information regarding Estrone and sus scrofa FDA-Labeled Indications and Dosage (Pediatric) in the drug label.
Off-Label Use and Dosage (Pediatric)
Guideline-Supported Use
There is limited information regarding Off-Label Guideline-Supported Use of Estrone and sus scrofa in pediatric patients.
Non–Guideline-Supported Use
There is limited information regarding Off-Label Non–Guideline-Supported Use of Estrone and sus scrofa in pediatric patients.
Contraindications
There is limited information regarding Estrone and sus scrofa Contraindications in the drug label.
Warnings
- If pregnant or breast-feeding, ask a health care professional before use.
- Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away.
- Do not use if tamper evident seal is broken or missing.
- Store in cool, dry place
Adverse Reactions
Clinical Trials Experience
There is limited information regarding Estrone and sus scrofa Clinical Trials Experience in the drug label.
Postmarketing Experience
There is limited information regarding Estrone and sus scrofa Postmarketing Experience in the drug label.
Drug Interactions
There is limited information regarding Estrone and sus scrofa Drug Interactions in the drug label.
Use in Specific Populations
Pregnancy
Pregnancy Category (FDA):
There is no FDA guidance on usage of Estrone and sus scrofa in women who are pregnant.
Pregnancy Category (AUS):
There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of Estrone and sus scrofa in women who are pregnant.
Labor and Delivery
There is no FDA guidance on use of Estrone and sus scrofa during labor and delivery.
Nursing Mothers
There is no FDA guidance on the use of Estrone and sus scrofa in women who are nursing.
Pediatric Use
There is no FDA guidance on the use of Estrone and sus scrofa in pediatric settings.
Geriatic Use
There is no FDA guidance on the use of Estrone and sus scrofa in geriatric settings.
Gender
There is no FDA guidance on the use of Estrone and sus scrofa with respect to specific gender populations.
Race
There is no FDA guidance on the use of Estrone and sus scrofa with respect to specific racial populations.
Renal Impairment
There is no FDA guidance on the use of Estrone and sus scrofa in patients with renal impairment.
Hepatic Impairment
There is no FDA guidance on the use of Estrone and sus scrofa in patients with hepatic impairment.
Females of Reproductive Potential and Males
There is no FDA guidance on the use of Estrone and sus scrofa in women of reproductive potentials and males.
Immunocompromised Patients
There is no FDA guidance one the use of Estrone and sus scrofa in patients who are immunocompromised.
Administration and Monitoring
Administration
Monitoring
There is limited information regarding Estrone and sus scrofa Monitoring in the drug label.
IV Compatibility
There is limited information regarding the compatibility of Estrone and sus scrofa and IV administrations.
Overdosage
There is limited information regarding Estrone and sus scrofa overdosage. If you suspect drug poisoning or overdose, please contact the National Poison Help hotline (1-800-222-1222) immediately.
Pharmacology
Estrone and sus scrofa
| |
Systematic (IUPAC) name | |
(8R,9S,13S,14S)-3-hydroxy-13-methyl- 6,7,8,9,11,12,13,14,15,16- decahydrocyclopenta[a]phenanthren- 17- one | |
Identifiers | |
CAS number | |
ATC code | G03 G03CC04 (WHO) |
PubChem | |
DrugBank | |
Chemical data | |
Formula | Template:OrganicBox atomTemplate:OrganicBox atomTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBox atomTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBox |
Mol. mass | 270.366 g/mol |
SMILES | & |
Physical data | |
Melt. point | 254.5 °C (490 °F) |
Pharmacokinetic data | |
Bioavailability | ? |
Protein binding | >95% |
Metabolism | ? |
Half life | 19 hours |
Excretion | ? |
Therapeutic considerations | |
Pregnancy cat. |
? |
Legal status |
[[Prescription drug|Template:Unicode-only]](US) |
Routes | ? |
Mechanism of Action
There is limited information regarding Estrone and sus scrofa Mechanism of Action in the drug label.
Structure
There is limited information regarding Estrone and sus scrofa Structure in the drug label.
Pharmacodynamics
There is limited information regarding Estrone and sus scrofa Pharmacodynamics in the drug label.
Pharmacokinetics
There is limited information regarding Estrone and sus scrofa Pharmacokinetics in the drug label.
Nonclinical Toxicology
There is limited information regarding Estrone and sus scrofa Nonclinical Toxicology in the drug label.
Clinical Studies
There is limited information regarding Estrone and sus scrofa Clinical Studies in the drug label.
How Supplied
There is limited information regarding Estrone and sus scrofa How Supplied in the drug label.
Storage
- Store in cool, dry place.
Images
Drug Images
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Package and Label Display Panel
{{#ask: Label Page::Estrone and sus scrofa |?Label Name |format=template |template=DrugLabelImages |mainlabel=- |sort=Label Page }}
Patient Counseling Information
- 10 drops orally, 3 times a day. Consult a physician for use in children under 12 years of age.
Precautions with Alcohol
Alcohol-Estrone and sus scrofa interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.
Brand Names
- ESTROGEN ®[1]
Look-Alike Drug Names
There is limited information regarding Estrone and sus scrofa Look-Alike Drug Names in the drug label.
Drug Shortage Status
Price
References
The contents of this FDA label are provided by the National Library of Medicine.
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