Magaldrate

Magaldrate

Clinical data
AHFS/Drugs.com	Micromedex Detailed Consumer Information
MedlinePlus	a682683
Pregnancy category	C
Routes of administration	Oral
ATC code	A02AD02 (WHO) A02AF01 (WHO) (combination with antiflatulents)
Legal status
Legal status	In general: Over-the-counter (OTC)
Pharmacokinetic data
Bioavailability	Negligible
Metabolism	Nil
Excretion	Fecal and renal
Identifiers
IUPAC name Magnesium aluminate monohydrate
CAS Number	1317-26-6 Y
PubChem CID	6336542
ChemSpider	4891688 Y
UNII	6V88E24N5T
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}
Chemical and physical data
Formula	AlMg2(OH)7·H2O
Molar mass	212.66 g/mol
InChI InChI=1S/Al.Mg.2H2O/h;;2*1H2/p-1 Y Key:SXSTVPXRZQQBKQ-UHFFFAOYSA-M Y
(verify)

WikiDoc Resources for Magaldrate
Articles
Most recent articles on Magaldrate Most cited articles on Magaldrate Review articles on Magaldrate Articles on Magaldrate in N Eng J Med, Lancet, BMJ
Media
Powerpoint slides on Magaldrate Images of Magaldrate Photos of Magaldrate Podcasts & MP3s on Magaldrate Videos on Magaldrate
Evidence Based Medicine
Cochrane Collaboration on Magaldrate Bandolier on Magaldrate TRIP on Magaldrate
Clinical Trials
Ongoing Trials on Magaldrate at Clinical Trials.gov Trial results on Magaldrate Clinical Trials on Magaldrate at Google
Guidelines / Policies / Govt
US National Guidelines Clearinghouse on Magaldrate NICE Guidance on Magaldrate NHS PRODIGY Guidance FDA on Magaldrate CDC on Magaldrate
Books
Books on Magaldrate
News
Magaldrate in the news Be alerted to news on Magaldrate News trends on Magaldrate
Commentary
Blogs on Magaldrate
Definitions
Definitions of Magaldrate
Patient Resources / Community
Patient resources on Magaldrate Discussion groups on Magaldrate Patient Handouts on Magaldrate Directions to Hospitals Treating Magaldrate Risk calculators and risk factors for Magaldrate
Healthcare Provider Resources
Symptoms of Magaldrate Causes & Risk Factors for Magaldrate Diagnostic studies for Magaldrate Treatment of Magaldrate
Continuing Medical Education (CME)
CME Programs on Magaldrate
International
Magaldrate en Espanol Magaldrate en Francais
Business
Magaldrate in the Marketplace Patents on Magaldrate
Experimental / Informatics
List of terms related to Magaldrate

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Magaldrate (INN) is a common antacid drug that is used for the treatment of duodenal and gastric ulcers, esophagitis from gastroesophageal reflux.

Available forms

Magaldrate is available in the form of oral suspension or tablets.

Pharmacology

Magaldrate is a hydroxymagnesium aluminate complex that is converted rapidly in gastric acid to Mg(OH)₂ and Al(OH)₃, which are absorbed poorly and thus provide a sustained antacid effect.

Interactions and adverse reactions

Magaldrate may negatively influence drugs like tetracyclines, benzodiazepines, and indomethacin. High doses or prolonged usage may lead to an increment of defecation and a reduction in feces consistence. In some cases it can alter the functionality of the gastrointestinal tract, occasionally provoking constipation or diarrhea.

Brand names

The drug is sold with the following brand names: Digecid Plus (Beximco Pharma, Bangladesh), Marlox Plus (Incepta pharma Bangladesh), Gastid (SK+F, Bangladesh), Novelta (Bangladesh), Gadral (Italy); Magaltop (Italy); Magralibi (Italy); Mylanta (Australia); Riopan (Argentina, Austria, Brazil, Egypt, Germany, Italy, Mexico, Belgium, Switzerland, Greece).

References

Template:Gastrointestinal-drug-stub