Oxaceprol: Difference between revisions

Jump to navigation Jump to search
← Older edit
VisualWikitext
WikiBot (talk | contribs)
Bots, Bureaucrats, bureaucrats, interwiki, nocaptcha, Administrators
57,550 edits
m Robot: Automated text replacement (-{{SIB}} +, -{{EH}} +, -{{EJ}} +, -{{Editor Help}} +, -{{Editor Join}} +)
WikiBot (talk | contribs)
Bots, Bureaucrats, bureaucrats, interwiki, nocaptcha, Administrators
57,550 edits
m Protected "Oxaceprol": Bot: Protecting all pages from category Drug ([Edit=Allow only administrators] (indefinite) [Move=Allow only administrators] (indefinite))
 
(4 intermediate revisions by one other user not shown)
Line 1: Line 1:
{{Drugbox
{{Drugbox
| IUPAC_name       = (2S,4R)-1-acetyl-4-hydroxypyrrolidine-2-carboxylic acid
| verifiedrevid = 447917039
| image             = Oxaceprol.png
| IUPAC_name = (4''R'')-1-acetyl-4-hydroxy-<small>L</small>-proline
| width             = 120px
| image = Oxaceprol.png
| CAS_number        = 33996-33-7
| width = 200px
| ATC_prefix        = D11
 
| ATC_suffix        = AX09
<!--Clinical data-->
| PubChem          = 65784
| tradename =
| ATC_supplemental  = {{ATC|M01|AX24}}
| Drugs.com = {{drugs.com|international|oxaceprol}}
| DrugBank          =
| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X -->
| C=7|H=11|N=1|O=4
| pregnancy_US = <!-- A / B            / C / D / X -->
| molecular_weight  = 172.159 g/mol
| pregnancy_category =   
| bioavailability  =
| legal_AU = <!-- Unscheduled / S2 / S3 / S4 / S5 / S6 / S7 / S8 / S9 -->
| protein_bound    =
| legal_CA = <!--            / Schedule I, II, III, IV, V, VI, VII, VIII -->
| metabolism        =
| legal_UK = <!-- GSL        / P      / POM / CD / Class A, B, C -->
| elimination_half-life =
| legal_US = <!-- OTC                  / Rx-only  / Schedule I, II, III, IV, V -->
| excretion        =
| legal_status = 
| pregnancy_AU     = <!-- A / B1 / B2 / B3 / C / D / X -->
| routes_of_administration = 
| pregnancy_US     = <!-- A / B            / C / D / X -->
 
| pregnancy_category=   
<!--Pharmacokinetic data-->
| legal_AU         = <!-- Unscheduled / S2 / S3 / S4 / S5 / S6 / S7 / S8 / S9 -->
| bioavailability = 
| legal_CA         = <!--            / Schedule I, II, III, IV, V, VI, VII, VIII -->
| protein_bound = 
| legal_UK         = <!-- GSL        / P      / POM / CD / Class A, B, C -->
| metabolism = 
| legal_US         = <!-- OTC                  / Rx-only  / Schedule I, II, III, IV, V -->
| elimination_half-life = 
| legal_status      =  
| excretion = 
| routes_of_administration =  
 
<!--Identifiers-->
| CAS_number_Ref = {{cascite|correct|??}}
| CAS_number = 33996-33-7
| ATC_prefix = D11
| ATC_suffix = AX09
| ATC_supplemental =  {{ATC|M01|AX24}}
| PubChem = 65784
| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
| DrugBank = 
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = Q0XV76B96L
| KEGG_Ref = {{keggcite|correct|kegg}}
| KEGG = D07215
| ChemSpiderID     = 59203
| ChEMBL = 1407356
 
<!--Chemical data-->
| C=7 | H=11 | N=1 | O=4
| molecular_weight = 172.159 g/mol
| smiles            = CC(=O)N1C[C@@H](C[C@H]1C(=O)O)O
| InChI            = 1/C7H11NO4/c1-4(9)8-3-5(10)2-6(8)7(11)12/h5-6,10H,2-3H2,1H3,(H,11,12)/t5-,6+/m1/s1
| InChIKey          = BAPRUDZDYCKSOQ-RITPCOANBI
| StdInChI          = 1S/C7H11NO4/c1-4(9)8-3-5(10)2-6(8)7(11)12/h5-6,10H,2-3H2,1H3,(H,11,12)/t5-,6+/m1/s1
| StdInChIKey      = BAPRUDZDYCKSOQ-RITPCOANSA-N
| synonyms = <small>(2''S'',4''R'')-1-acetyl-4-hydroxypyrrolidine-2-carboxylic acid</small>
}}
}}
__NOTOC__
{{SI}}
{{SI}}
 
{{CMG}}
 
==Overview==
==Overview==
'''Oxaceprol''' is an anti-inflammatory drug used in the treatment of [[osteoarthritis]].<ref name="pmid10791619">{{cite journal |author=Herrmann G, Steeger D, Klasser M, ''et al'' |title=Oxaceprol is a well-tolerated therapy for osteoarthritis with efficacy equivalent to diclofenac |journal=Clin. Rheumatol. |volume=19 |issue=2 |pages=99-104 |year=2000 |pmid=10791619 |doi=}}</ref>
'''Oxaceprol''' is an anti-inflammatory drug used in the treatment of [[osteoarthritis]].<ref name="pmid10791619">{{cite journal |author=Herrmann G |title=Oxaceprol is a well-tolerated therapy for osteoarthritis with efficacy equivalent to diclofenac |journal=Clin. Rheumatol. |volume=19 |issue=2 |pages=99–104 |year=2000 |pmid=10791619 |doi=10.1007/s100670050025 |author-separator=, |author2=Steeger D |author3=Klasser M |display-authors=3 |last4=Wirbitzky |first4=J. |last5=f&#x000Fc;Rst |first5=M. |last6=Venbrocks |first6=R. |last7=Rohde |first7=H. |last8=Jungmichel |first8=D. |last9=Hildebrandt |first9=H. D.}}</ref> It is derived from [[L-proline]], a DNA-encoded [[amino acid]]. The active effect of Oxaceprol is to inhibit the adhesion and migration of [[white blood cell]]s.


==References==
==References==
<references/>
{{reflist|2}}


{{Other dermatological preparations}}
{{Other dermatological preparations}}
{{Anti-inflammatory and antirheumatic products}}
{{Anti-inflammatory and antirheumatic products}}


[[Category:Carboxylic acids]]
[[Category:Pyrrolidines]]
[[Category:Pyrrolidines]]
{{WikiDoc Help Menu}}
[[Category:Alcohols]]
{{WikiDoc Sources}}
[[Category:Drug]]

Latest revision as of 16:51, 20 August 2015

Oxaceprol
Clinical data
Synonyms(2S,4R)-1-acetyl-4-hydroxypyrrolidine-2-carboxylic acid
AHFS/Drugs.comInternational Drug Names
ATC code
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
E number{{#property:P628}}
ECHA InfoCard{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
FormulaC7H11NO4
Molar mass172.159 g/mol
3D model (JSmol)
  (verify)

WikiDoc Resources for Oxaceprol

Articles

Most recent articles on Oxaceprol

Most cited articles on Oxaceprol

Review articles on Oxaceprol

Articles on Oxaceprol in N Eng J Med, Lancet, BMJ

Media

Powerpoint slides on Oxaceprol

Images of Oxaceprol

Photos of Oxaceprol

Podcasts & MP3s on Oxaceprol

Videos on Oxaceprol

Evidence Based Medicine

Cochrane Collaboration on Oxaceprol

Bandolier on Oxaceprol

TRIP on Oxaceprol

Clinical Trials

Ongoing Trials on Oxaceprol at Clinical Trials.gov

Trial results on Oxaceprol

Clinical Trials on Oxaceprol at Google

Guidelines / Policies / Govt

US National Guidelines Clearinghouse on Oxaceprol

NICE Guidance on Oxaceprol

NHS PRODIGY Guidance

FDA on Oxaceprol

CDC on Oxaceprol

Books

Books on Oxaceprol

News

Oxaceprol in the news

Be alerted to news on Oxaceprol

News trends on Oxaceprol

Commentary

Blogs on Oxaceprol

Definitions

Definitions of Oxaceprol

Patient Resources / Community

Patient resources on Oxaceprol

Discussion groups on Oxaceprol

Patient Handouts on Oxaceprol

Directions to Hospitals Treating Oxaceprol

Risk calculators and risk factors for Oxaceprol

Healthcare Provider Resources

Symptoms of Oxaceprol

Causes & Risk Factors for Oxaceprol

Diagnostic studies for Oxaceprol

Treatment of Oxaceprol

Continuing Medical Education (CME)

CME Programs on Oxaceprol

International

Oxaceprol en Espanol

Oxaceprol en Francais

Business

Oxaceprol in the Marketplace

Patents on Oxaceprol

Experimental / Informatics

List of terms related to Oxaceprol

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Oxaceprol is an anti-inflammatory drug used in the treatment of osteoarthritis.[1] It is derived from L-proline, a DNA-encoded amino acid. The active effect of Oxaceprol is to inhibit the adhesion and migration of white blood cells.

References

  1. ↑ Herrmann G; Steeger D; Klasser M; et al. (2000). "Oxaceprol is a well-tolerated therapy for osteoarthritis with efficacy equivalent to diclofenac". Clin. Rheumatol. 19 (2): 99–104. doi:10.1007/s100670050025. PMID 10791619. Unknown parameter |author-separator= ignored (help)
Retrieved from "https://www.wikidoc.org/index.php?title=Oxaceprol&oldid=1137181"