Pemirolast: Difference between revisions

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| PubChem = 57697
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| DrugBank = DB00885
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__NOTOC__
{{SI}}
{{CMG}}
==Overview==
==Overview==
 
'''Pemirolast''' ([[International Nonproprietary Name|INN]]) is a [[mast cell stabilizer]] used as an anti-allergic drug therapy. It is marketed under the tradenames '''Alegysal''' and '''Alamast'''.
'''Pemirolast''' ([[International Nonproprietary Name|INN]]) is an anti-allergic drug. It is marketed under the tradenames '''Alegysal''' and '''Alamast'''.


It has also been studied for the treatment of asthma.
It has also been studied for the treatment of asthma.


==References==
==References==
{{reflist|2}}  
{{reflist|2}}
 
*{{cite journal |author=Tinkelman DG, Berkowitz RB |title=A pilot study of pemirolast in patients with seasonal allergic rhinitis |journal=Ann Allergy |volume=66 |issue=2 |pages=162–5 |year=1991 |month=February |pmid=1994787 |doi= |url=}}
*{{cite journal |author=Kawashima T, Iwamoto I, Nakagawa N, Tomioka H, Yoshida S |title=Inhibitory effect of pemirolast, a novel antiallergic drug, on leukotriene C4 and granule protein release from human eosinophils |journal=Int. Arch. Allergy Immunol. |volume=103 |issue=4 |pages=405–9 |year=1994 |pmid=8130655 |doi= 10.1159/000236662|url=}}
*{{cite journal |author=Abelson MB, Berdy GJ, Mundorf T, Amdahl LD, Graves AL |title=Pemirolast potassium 0.1% ophthalmic solution is an effective treatment for allergic conjunctivitis: a pooled analysis of two prospective, randomized, double-masked, placebo-controlled, phase III studies |journal=J Ocul Pharmacol Ther |volume=18 |issue=5 |pages=475–88 |year=2002 |month=October |pmid=12419098 |doi=10.1089/10807680260362759 |url=}}
*{{cite journal |author=Kemp JP, Bernstein IL, Bierman CW, ''et al.'' |title=Pemirolast, a new oral nonbronchodilator drug for chronic asthma |journal=Ann Allergy |volume=68 |issue=6 |pages=488–91 |year=1992 |month=June |pmid=1610024 |doi= |url=}}
 
==External links==
*{{cite web | author = Mitsubishi Tanabe Pharma Corporation | year = 2007 | url = http://www.e-search.ne.jp/~jpr/PDF/MITSUB32.PDF | title = ALEGYSAL (English) | accessdate = 2008-09-02}}
*{{cite web | author = VISTAKON Pharmaceuticals, LLC | year = 2005 | url = http://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?id=3230 | title = ALAMAST (pemirolast potassium opthalmic solution) 0.1% | accessdate = 2008-09-02}}
 
{{Antihistamines}}
 
 
 


[[Category:H1 receptor antagonists]]
[[Category:H1 receptor antagonists]]
[[Category:Tetrazoles]]
[[Category:Tetrazoles]]
[[Category:Lactams]]
[[Category:Lactams]]
[[Category:Pyridopyrimidines]]
[[Category:Drug]]
 
 
{{respiratory-system-drug-stub}}

Latest revision as of 16:54, 20 August 2015

Pemirolast
Clinical data
Trade namesAlamast
AHFS/Drugs.comMonograph
Pregnancy
category
  • US: C (Risk not ruled out)
Routes of
administration		Oral, ophthalmic
ATC code
  • none
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEMBL
E number{{#property:P628}}
ECHA InfoCard{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
FormulaC10H8N6O
Molar mass228.21 g/mol
3D model (JSmol)
 ☒N☑Y (what is this?)  (verify)

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Pemirolast (INN) is a mast cell stabilizer used as an anti-allergic drug therapy. It is marketed under the tradenames Alegysal and Alamast.

It has also been studied for the treatment of asthma.

References

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