Ganglioneuroma staging: Difference between revisions
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{{Ganglioneuroma}} | {{Ganglioneuroma}} | ||
{{CMG}} | {{CMG}}{{AE}}{{SR}} | ||
==Overview== | ==Overview== | ||
According to the International Neuroblastoma Staging System (INSS), there are six stages of ganglioneuroma based on [[clinical]], radiologic, and [[surgical]] features.<ref name=staging>{{cite journal |last=Adam |first=O |last2=Boia |first2=ES |date=2007 |title=ganglioneuroma |url=http://www.jurnalulpediatrului.ro/pages/arhiva/39-40/39-40-IV-11.pdf |journal=jurnalul pediatrului |publisher= |volume=10 |issue=39-40|doi= |access-date=10 September 2015}}</ref> | |||
==Staging== | ==Staging== | ||
According to the International Neuroblastoma Staging System (INSS), there are six stages of ganglioneuroma based on [[clinical]], radiologic, and [[surgical]] features.<ref name=staging>{{cite journal |last=Adam |first=O |last2=Boia |first2=ES |date=2007 |title=ganglioneuroma |url=http://www.jurnalulpediatrului.ro/pages/arhiva/39-40/39-40-IV-11.pdf |journal=jurnalul pediatrului |publisher= |volume=10 |issue=39-40|doi= |access-date=10 September 2015}}</ref> | |||
'''Stage 1''' | |||
*Localized tumor confined to the area of origin | |||
*Complete gross excision, with or without microscopically residual disease | |||
*Identifiable [[ipsilateral]] and [[contralateral]] lymph node negative microscopically | |||
'''Stage 2A''' | |||
*Unilateral tumor with incomplete gross excision | |||
*Identifiable [[ipsilateral]] nonadherent [[lymph node]] negative microscopically | |||
'''Stage 2B''' | |||
*Unilateral tumor with complete or incomplete gross excision | |||
*Positive ipsilateral nonadherent lymph nodes | |||
*Identifiable [[contralateral]] lymph node negtive microscopically | |||
'''Stage 3''' | |||
*Tumor infiltrating across the midline (vertebral column) with or without regional [[lymph node]] involvement | |||
:{{or}} | |||
*Unilateral tumor with [[contralateral]] regional lymph node involvement | |||
:{{or}} | |||
*Midline tumor with bilateral regional [[lymph node]] involvement or extension by infiltration | |||
'''Stage 4''' | |||
*Dissemination of tumor to distant [[lymph nodes]], bone, bone marrow, liver or other organs (except as defined in stage 4S) | |||
'''Stage 4S''' | |||
*Localized primary tumor as defined for stage 1 or 2 with dissemination limited to liver, skin, and/or bone marrow (<10% tumor) in infants younger than 1 yr | |||
==References== | ==References== |
Latest revision as of 17:18, 15 September 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]
Overview
According to the International Neuroblastoma Staging System (INSS), there are six stages of ganglioneuroma based on clinical, radiologic, and surgical features.[1]
Staging
According to the International Neuroblastoma Staging System (INSS), there are six stages of ganglioneuroma based on clinical, radiologic, and surgical features.[1]
Stage 1
- Localized tumor confined to the area of origin
- Complete gross excision, with or without microscopically residual disease
- Identifiable ipsilateral and contralateral lymph node negative microscopically
Stage 2A
- Unilateral tumor with incomplete gross excision
- Identifiable ipsilateral nonadherent lymph node negative microscopically
Stage 2B
- Unilateral tumor with complete or incomplete gross excision
- Positive ipsilateral nonadherent lymph nodes
- Identifiable contralateral lymph node negtive microscopically
Stage 3
- Tumor infiltrating across the midline (vertebral column) with or without regional lymph node involvement
- OR
- Unilateral tumor with contralateral regional lymph node involvement
- OR
- Midline tumor with bilateral regional lymph node involvement or extension by infiltration
Stage 4
- Dissemination of tumor to distant lymph nodes, bone, bone marrow, liver or other organs (except as defined in stage 4S)
Stage 4S
- Localized primary tumor as defined for stage 1 or 2 with dissemination limited to liver, skin, and/or bone marrow (<10% tumor) in infants younger than 1 yr
References
- ↑ 1.0 1.1 Adam, O; Boia, ES (2007). "ganglioneuroma" (PDF). jurnalul pediatrului. 10 (39–40). Retrieved 10 September 2015.