Ganglioneuroma staging: Difference between revisions
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*Localized tumor confined to the area of origin | *Localized tumor confined to the area of origin | ||
*Complete gross excision, with or without microscopically residual disease | *Complete gross excision, with or without microscopically residual disease | ||
*Identifiable ipsilateral and contralateral lymph node negative microscopically | *Identifiable [[ipsilateral]] and [[contralateral]] lymph node negative microscopically | ||
'''Stage 2A''' | '''Stage 2A''' | ||
*Unilateral tumor with incomplete gross excision | *Unilateral tumor with incomplete gross excision | ||
*Identifiable ipsilateral nonadherent lymph node negative microscopically | *Identifiable [[ipsilateral]] nonadherent [[lymph node]] negative microscopically | ||
'''Stage 2B''' | '''Stage 2B''' | ||
*Unilateral tumor with complete or incomplete gross excision | *Unilateral tumor with complete or incomplete gross excision | ||
*Positive ipsilateral nonadherent lymph nodes | *Positive ipsilateral nonadherent lymph nodes | ||
*Identifiable contralateral lymph node negtive microscopically | *Identifiable [[contralateral]] lymph node negtive microscopically | ||
'''Stage 3''' | '''Stage 3''' | ||
*Tumor infiltrating across the midline (vertebral column) with or without regional lymph node involvement | *Tumor infiltrating across the midline (vertebral column) with or without regional [[lymph node]] involvement | ||
:or | :{{or}} | ||
*Unilateral tumor with | *Unilateral tumor with [[contralateral]] regional lymph node involvement | ||
:or | :{{or}} | ||
*Midline tumor with bilateral regional lymph node involvement or extension by infiltration | *Midline tumor with bilateral regional [[lymph node]] involvement or extension by infiltration | ||
'''Stage 4''' | '''Stage 4''' | ||
*Dissemination of tumor to distant lymph nodes, bone, bone marrow, liver or other organs (except as defined in stage 4S) | *Dissemination of tumor to distant [[lymph nodes]], bone, bone marrow, liver or other organs (except as defined in stage 4S) | ||
''' | '''Stage 4S''' | ||
*Localized primary tumor as defined for stage 1 or 2 with dissemination limited to liver, skin, and/or bone marrow (<10% tumor) in infants younger than 1 yr | *Localized primary tumor as defined for stage 1 or 2 with dissemination limited to liver, skin, and/or bone marrow (<10% tumor) in infants younger than 1 yr | ||
Latest revision as of 17:18, 15 September 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]
Overview
According to the International Neuroblastoma Staging System (INSS), there are six stages of ganglioneuroma based on clinical, radiologic, and surgical features.[1]
Staging
According to the International Neuroblastoma Staging System (INSS), there are six stages of ganglioneuroma based on clinical, radiologic, and surgical features.[1]
Stage 1
- Localized tumor confined to the area of origin
- Complete gross excision, with or without microscopically residual disease
- Identifiable ipsilateral and contralateral lymph node negative microscopically
Stage 2A
- Unilateral tumor with incomplete gross excision
- Identifiable ipsilateral nonadherent lymph node negative microscopically
Stage 2B
- Unilateral tumor with complete or incomplete gross excision
- Positive ipsilateral nonadherent lymph nodes
- Identifiable contralateral lymph node negtive microscopically
Stage 3
- Tumor infiltrating across the midline (vertebral column) with or without regional lymph node involvement
- OR
- Unilateral tumor with contralateral regional lymph node involvement
- OR
- Midline tumor with bilateral regional lymph node involvement or extension by infiltration
Stage 4
- Dissemination of tumor to distant lymph nodes, bone, bone marrow, liver or other organs (except as defined in stage 4S)
Stage 4S
- Localized primary tumor as defined for stage 1 or 2 with dissemination limited to liver, skin, and/or bone marrow (<10% tumor) in infants younger than 1 yr
References
- ↑ 1.0 1.1 Adam, O; Boia, ES (2007). "ganglioneuroma" (PDF). jurnalul pediatrului. 10 (39–40). Retrieved 10 September 2015.