Sandbox:DDx HEENT: Difference between revisions

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* 40-60 yo women
* Anemia and lymphopenia
* May have bone pain or respiratory symptoms
* Eosinophilia and neutrophiliae
 
* Positive warm-agglutinin  antibodies
* Painless thyroid nodule
* Elevated LDH and creatinine concentration
 
 
* Invasion of capsule and surrounding parenchyma/blood vessels on true cut biopsy
* Thick calcified capsule present
* Follicular/solid growth pattern with Hürthle cells, nuclear atypia, and increased mitotic activity on FNA
 
 
* Hypoechoic solid solitary mass on U/S
 
* RAS oncogene activation
* PAX8-PPAR gamma 1 genes rearrangement

Latest revision as of 20:51, 4 November 2015

  • Anemia and lymphopenia
  • Eosinophilia and neutrophiliae
  • Positive warm-agglutinin antibodies
  • Elevated LDH and creatinine concentration
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