Sandbox:DDx HEENT: Difference between revisions

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* 65 yo women
* Anemia and lymphopenia
* Rapidly enlarging neck mass
* Eosinophilia and neutrophiliae
* Neck pain, dyspnea, dysphagia, and hoarseness
* Positive warm-agglutinin  antibodies
* Constitutional symptoms
* Elevated LDH and creatinine concentration
 
* Tender hard nodular goiter
* Extensive lymphadenopathy
 
* Pleomorphic giant cells
* Connective tissue septae
* Necrosis and vascular invasion
* Increased mitotic activity
* Rhabdoid inclusions
* Well-differentiated cells palisading at necrotic edges
 
* BRAF gene mutation
* p53 gene mutation

Latest revision as of 20:51, 4 November 2015

  • Anemia and lymphopenia
  • Eosinophilia and neutrophiliae
  • Positive warm-agglutinin antibodies
  • Elevated LDH and creatinine concentration