Sandbox:DDx HEENT: Difference between revisions

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* 30-50 yo women, self limited
* Anemia and lymphopenia
* Subacute onset
* Eosinophilia and neutrophiliae
* Painful neck swelling with fever, malaise, and fatigue
* Positive warm-agglutinin  antibodies
* Symptoms of thyrotoxicosis followed by transient hypothyroid symptoms
* Elevated LDH and creatinine concentration
 
* Tender mid-line neck swelling
 
 
* Initial increase in T3 and T4 with decreased TSH
* Followed by decrease in T3 and T4 with increased TSH
* Return to normal baseline thyroid function
 
* Poorly defined hypechogenic region on U/S
* Decreased vascularity in the affected areas
* Low uptake thyroid iodine scan
 
* Accumulation of neutrophils with follicular destruction and colloid depletion
* Noncaseating granulomas formation
* Fibrosis may develop
 
* HLA-B35

Latest revision as of 20:51, 4 November 2015

  • Anemia and lymphopenia
  • Eosinophilia and neutrophiliae
  • Positive warm-agglutinin antibodies
  • Elevated LDH and creatinine concentration
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