Sandbox:DDx HEENT: Difference between revisions

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* 15-30 yo women
* Anemia and lymphopenia
* Fatigue, weight gain, cold intolerance, constipation, myopathy, depression,  menorrhagia, and infertility
* Eosinophilia and neutrophiliae
 
* Positive warm-agglutinin  antibodies  
* Nontender mild neck swelling
* Elevated LDH and creatinine concentration
* Puffy face, bradycardia, and dry skin
 
* Decreased T3/T4 and increased TSH
* Anti-thyroid peroxidase antibodies
* Elevated cholesterol levels
 
* Hypoechoic thyroid gland with coarse or "micronodular" echotexture on U/S
* Increased vascularity of the gland
 
* Extensive T cell lymphocytic infiltrate
* Nuclear clearing
* Germinal center formation
* Hürthle cells and giant cells
* Fibrosis
 
 
* HLA-DR5
* CTLA4

Latest revision as of 20:51, 4 November 2015

  • Anemia and lymphopenia
  • Eosinophilia and neutrophiliae
  • Positive warm-agglutinin antibodies
  • Elevated LDH and creatinine concentration
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