Sandbox: DDx Kidney mass: Difference between revisions

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* 40-50 yo patients
* May have refractory hypertension, palpitations, headache, diaphoresis, anxiety,  weight loss, and flank pain 
* MEN, von Hippel–Lindau disease, tuberous sclerosis, or neurofibromatosis


* Pallor
* Fever, chills, night sweats, and abdominal pain
* Tachycardia
* Hematuria, pallor, and weight loss


* Elevated serum catecholamines and metanephrines


* Large, heterogeneous mass  on CT
* Costovertebral tenderness
* Areas of necrosis and cystic change
 
* on CT
 
* Elevated WBC count
* Elevated ESR and CRP
 
* Well defined hypoechoic area within the corticomedullary parenchyma on U/S
* Well defined mass of low attenuation with a thick, irregular wall or pseudocapsule on CT
 
* Not applicable
 
Angiosarcoma
 


* VHL, RET, NF1SDHB and SDHD gene mutation


==Nonmalignant causes==
==Nonmalignant causes==
anaplastic sarcoma clear cell sarcoma mesoblastic nephroma metanephric stromal tumor nephroblastomatosis / nephrogenic rests neuroblastoma oncocytoid carcinoma after neuroblastoma ossifying
anaplastic sarcoma clear cell sarcoma mesoblastic nephroma metanephric stromal tumor nephroblastomatosis / nephrogenic rests neuroblastoma oncocytoid carcinoma after neuroblastoma ossifying

Latest revision as of 20:52, 9 November 2015

  • Fever, chills, night sweats, and abdominal pain
  • Hematuria, pallor, and weight loss


  • Costovertebral tenderness


  • Elevated WBC count
  • Elevated ESR and CRP
  • Well defined hypoechoic area within the corticomedullary parenchyma on U/S
  • Well defined mass of low attenuation with a thick, irregular wall or pseudocapsule on CT
  • Not applicable

Angiosarcoma


Nonmalignant causes

anaplastic sarcoma clear cell sarcoma mesoblastic nephroma metanephric stromal tumor nephroblastomatosis / nephrogenic rests neuroblastoma oncocytoid carcinoma after neuroblastoma ossifying