Sandbox: DDx Kidney mass: Difference between revisions

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* 50-60 yo male
* Asymptomatic
* Incidental finding on imaging
* May have hematuria and flank pain
* Palpable flank mass


* Fever, chills, night sweats, and abdominal pain
* Hematuria, pallor, and weight loss




* Costovertebral tenderness


* Large well demarcated tumors
 
* Large hetrogenous mass  
* Elevated WBC count
* Perinephric fat-stranding
* Elevated ESR and CRP
* Calcification
 
* Well defined hypoechoic area within the corticomedullary parenchyma on U/S
* Well defined mass of low attenuation with a thick, irregular wall or pseudocapsule on CT
 
* Not applicable
 
Angiosarcoma




* Cells arranged in nests
* Granular eosinophilic cytoplasm 
* Nuclei uniform and round with no pleomorphism


* KIT positive
* Multiple losses of entire chromosomes 1, 2, 6, 10, 13, 17, 21 and Y
==Nonmalignant causes==
==Nonmalignant causes==
anaplastic sarcoma clear cell sarcoma mesoblastic nephroma metanephric stromal tumor nephroblastomatosis / nephrogenic rests neuroblastoma oncocytoid carcinoma after neuroblastoma ossifying
anaplastic sarcoma clear cell sarcoma mesoblastic nephroma metanephric stromal tumor nephroblastomatosis / nephrogenic rests neuroblastoma oncocytoid carcinoma after neuroblastoma ossifying

Latest revision as of 20:52, 9 November 2015

  • Fever, chills, night sweats, and abdominal pain
  • Hematuria, pallor, and weight loss


  • Costovertebral tenderness


  • Elevated WBC count
  • Elevated ESR and CRP
  • Well defined hypoechoic area within the corticomedullary parenchyma on U/S
  • Well defined mass of low attenuation with a thick, irregular wall or pseudocapsule on CT
  • Not applicable

Angiosarcoma


Nonmalignant causes

anaplastic sarcoma clear cell sarcoma mesoblastic nephroma metanephric stromal tumor nephroblastomatosis / nephrogenic rests neuroblastoma oncocytoid carcinoma after neuroblastoma ossifying