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! style="background: #4479BA; width: 250px; color: #FFFFFF;"|'''Prognostic Factor'''
! style="background: #4479BA; width: 400px; color: #FFFFFF;"|'''Classification'''
 
! style="background: #4479BA; width: 600px; color: #FFFFFF;"|'''Description'''
! style="background: #4479BA; width: 600px; color: #FFFFFF;"|'''Description'''
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|-
 
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center |  
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''Age'''|| style="padding: 5px 5px; background: #F5F5F5;" |
'''Normal'''
:* Older age at the time of diagnosis is associated with a worse prognosis.
| style="padding: 5px 5px; background: #F5F5F5;"|
 
:*The expression of zeta-chain-associated protein kinase 70 (ZAP) is associated with a worse prognosis.
|-
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| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''Prehypertension'''
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''Gender'''|| style="padding: 5px 5px; background: #F5F5F5;"|
| style="padding: 5px 5px; background: #F5F5F5;"|
:* Males are associated with a worse prognosis when compared to females.
:*The expression of zeta-chain-associated protein kinase 70 (ZAP) is associated with a worse prognosis.
|-
 
 
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''Performance status'''|| style="padding: 5px 5px; background: #F5F5F5;"|
:* Patient's poor [[performance status]] is associated with a worse prognosis.
|-
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| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''Stage 1 hypertension'''
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''Stage'''|| style="padding: 5px 5px; background: #F5F5F5;" |
| style="padding: 5px 5px; background: #F5F5F5;"|
:*Binet stages B and C or Rai stages 2-4 are associated with a worse prognosis.
:*The expression of zeta-chain-
 
|-
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| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center |  
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''Lymphocyte doubling time'''|| style="padding: 5px 5px; background: #F5F5F5;" |
'''Isolated diastolic hypertension'''
:*A rapid [[lymphocyte]] doubling time is associated with a worse prognosis.
| style="padding: 5px 5px; background: #F5F5F5;"|
 
:*The expression of zeta-chain-associated protein kinase 70 (ZAP) is associated with a worse prognosis.
|-
|-
 
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''Stage 2 hypertension'''
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''Genetic mutations'''|| style="padding: 5px 5px; background: #F5F5F5;"|
| style="padding: 5px 5px; background: #F5F5F5;"|
:*Deletion of [[chromosome 17]] short arm and [[chromosome 11]] long arm are associated with a worse prognosis.
:*The expression of zeta-chain-associated protein kinase 70 (ZAP) is associated with a worse prognosis.
 
|-
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''Isolated systolic hypertension'''
| style="padding: 5px 5px; background: #F5F5F5;"|
:*The expression of zeta-chain-


|style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''Prolymphocytes percent'''|| style="padding: 5px 5px; background: #F5F5F5;" |
:*An increased percentage of [[prolymphocyte]]s is associated with a worse prongnosis.


|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''Histological analysis'''|| style="padding: 5px 5px; background: #F5F5F5;"|
:*Diffuse [[histology]] on [[bone marrow aspiration]] is associated with a worse prognosis.
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''Lactate dehydrogenase (LDH) level'''|| style="padding: 5px 5px; background: #F5F5F5;"|
:*Elevated level of [[LDH]] is associated with a worse prognosis.
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''β2-microglobulin level '''|| style="padding: 5px 5px; background: #F5F5F5;"|
:*Elevated level of β2-microglobulin level is associated with a worse prognosis.
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''Lymphocyte surface markers'''|| style="padding: 5px 5px; background: #F5F5F5;"|
:*Over expression of [[CD38]] is associated with a worse prognosis.
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''Immunoglobulin (Ig)VH gene'''|| style="padding: 5px 5px; background: #F5F5F5;"|
:*The absence of IgVH [[gene]] mutation is associated with a worse prognosis.
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''Membrane-bound proteins'''|| style="padding: 5px 5px; background: #F5F5F5;"|
:*The expression of zeta-chain-associated protein kinase 70 (ZAP) is associated with a worse prognosis.
|}
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Latest revision as of 20:19, 10 November 2015

Risk Factors

Classification Description

Normal

  • The expression of zeta-chain-associated protein kinase 70 (ZAP) is associated with a worse prognosis.
Prehypertension
  • The expression of zeta-chain-associated protein kinase 70 (ZAP) is associated with a worse prognosis.
Stage 1 hypertension
  • The expression of zeta-chain-

Isolated diastolic hypertension

  • The expression of zeta-chain-associated protein kinase 70 (ZAP) is associated with a worse prognosis.
Stage 2 hypertension
  • The expression of zeta-chain-associated protein kinase 70 (ZAP) is associated with a worse prognosis.
Isolated systolic hypertension
  • The expression of zeta-chain-