Sandbox: Bone DDx: Difference between revisions

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* 40-50 yo women
* 55-60 yo males
* History of hyperparathyroidism
* Back pain
* Pathological fracture
* Palpable vertebral mass


* Well-defined, purely lytic lesions on X ray
* Little reactive bone lesion
* Solid, cystic, or mixed component on MRI


* Discrete, solitary mass male 55 years
* Pain at the site of the skeletal lesion
* Bone destruction


 
* Well-defined, “punched-out” lytic lesions
* Fibrosis
* Marked erosion, expansion, and destruction of bone cortex
* Giant cells with round to oval nuclei and nucleoli
* Thick ridging around the periphery
* Elevated number of osteoblast and osteoclast
* “Soap bubble” appearance

Latest revision as of 20:27, 24 November 2015

  • 55-60 yo males
  • Back pain
  • Pathological fracture
  • Palpable vertebral mass


  • Discrete, solitary mass male 55 years
  • Pain at the site of the skeletal lesion
  • Bone destruction
  • Well-defined, “punched-out” lytic lesions
  • Marked erosion, expansion, and destruction of bone cortex
  • Thick ridging around the periphery
  • “Soap bubble” appearance
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