Sandbox: Bone DDx: Difference between revisions

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* Progressive bone pain  
* 55-60 yo males
* Bony swelling
* Back pain
* Restricted range of movement in affected limb
* Pathological fracture
* Palpable vertebral mass




* Chondroid, myxoid, and fibrous tissue components
* Discrete, solitary mass male 55 years
* Spindle cells or stellate cells in a myxoid or chondroid stroma
* Pain at the site of the skeletal lesion
* Pseudolobulated architecture
* Bone destruction
* Lobules with hypocellular centers and hypercellular peripheries
* Scattered calcifications


 
* Well-defined, “punched-out” lytic lesions
* Metaphyseal region of long bones
* Marked erosion, expansion, and destruction of bone cortex
* Lobulated, eccentric radiolucent lesion with a well defined sclerotic margin
* Thick ridging around the periphery
* No periosteal reaction
* “Soap bubble” appearance
* Presence of septations, pseudotrabeculation, and geographic bone destruction
 
 
* SOX9 +ve

Latest revision as of 20:27, 24 November 2015

  • 55-60 yo males
  • Back pain
  • Pathological fracture
  • Palpable vertebral mass


  • Discrete, solitary mass male 55 years
  • Pain at the site of the skeletal lesion
  • Bone destruction
  • Well-defined, “punched-out” lytic lesions
  • Marked erosion, expansion, and destruction of bone cortex
  • Thick ridging around the periphery
  • “Soap bubble” appearance
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