Sandbox: Bone DDx: Difference between revisions

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* 50-70 yo males
* 55-60 yo males
* Deep, achy,  dull pain
* Back pain
* Night time bone pain
* Pathological fracture
* Limited range of joints motion
* Palpable vertebral mass
* Pathologic fracture


* Palpable lump or local mass effect


* Large calcified lesions
* Discrete, solitary mass male 55 years
* Thin and expanded bone
* Pain at the site of the skeletal lesion
* Multiple surface erosions
* Bone destruction
* Cortical thickening


 
* Well-defined, “punched-out” lytic lesions
* Lytic intralesional calcification
* Marked erosion, expansion, and destruction of bone cortex
* Endosteal scalloping
* Thick ridging around the periphery
* Moth eaten appearance
* “Soap bubble” appearance
* Cortical remodelling, thickening and periosteal reaction
 
 
Bi-nucleation.
Hypochromatic enlarged nuclei.
Infiltration of lamellar bone ("invasion")
Increased cellularity

Latest revision as of 20:27, 24 November 2015

  • 55-60 yo males
  • Back pain
  • Pathological fracture
  • Palpable vertebral mass


  • Discrete, solitary mass male 55 years
  • Pain at the site of the skeletal lesion
  • Bone destruction
  • Well-defined, “punched-out” lytic lesions
  • Marked erosion, expansion, and destruction of bone cortex
  • Thick ridging around the periphery
  • “Soap bubble” appearance
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