Sandbox: Bone DDx: Difference between revisions

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* 20 yo patients
* 55-60 yo males
* Painless, slowly growing mass
* Back pain
* Pathological fracture
* Palpable vertebral mass




* Lytic bone lesions with geographic pattern of bone destruction on X ray
* Discrete, solitary mass male 55 years
* Located at metaphysis of long bones
* Pain at the site of the skeletal lesion
* Narrow zone of transition
* Bone destruction
* Non-sclerotic margins
* Internal pseudotrabeculation


 
* Well-defined, “punched-out” lytic lesions
* Mature, bland fibroblasts
* Marked erosion, expansion, and destruction of bone cortex
* Little cellularity, no pleomorphism
* Thick ridging around the periphery
* Abundant collagenous stroma
* “Soap bubble” appearance
* Thin walled, dilated vascular channels

Latest revision as of 20:27, 24 November 2015

  • 55-60 yo males
  • Back pain
  • Pathological fracture
  • Palpable vertebral mass


  • Discrete, solitary mass male 55 years
  • Pain at the site of the skeletal lesion
  • Bone destruction
  • Well-defined, “punched-out” lytic lesions
  • Marked erosion, expansion, and destruction of bone cortex
  • Thick ridging around the periphery
  • “Soap bubble” appearance
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