Sandbox: Bone DDx: Difference between revisions

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* 10-30 yo patients
* 55-60 yo males
* Asymptomatic
* Back pain
* Pathological fracture
* Pathological fracture  
* Maffuci syndrome and Ollier disease
* Palpable vertebral mass


* Located in the medullary cavity at the metaphyseal region
* Small lytic lesions, sharply defined scalloped margin, and narrow zone of transition
* Expansion of the overlying cortex
* Rings and arcs of calcifications
* No periosteal reaction


* Discrete, solitary mass male 55 years
* Pain at the site of the skeletal lesion
* Bone destruction


 
* Well-defined, “punched-out” lytic lesions
* Lobules of hyaline cartilage
* Marked erosion, expansion, and destruction of bone cortex
* Surrounded by fibrous tissue and bone
* Thick ridging around the periphery
* Bony extension into the cartilage
* “Soap bubble” appearance
* Myxoid change, hypercellularity, and binucleation
* Calcification, endochondral ossification, and necrosis

Latest revision as of 20:27, 24 November 2015

  • 55-60 yo males
  • Back pain
  • Pathological fracture
  • Palpable vertebral mass


  • Discrete, solitary mass male 55 years
  • Pain at the site of the skeletal lesion
  • Bone destruction
  • Well-defined, “punched-out” lytic lesions
  • Marked erosion, expansion, and destruction of bone cortex
  • Thick ridging around the periphery
  • “Soap bubble” appearance
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