Sandbox: Bone DDx: Difference between revisions

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* 1-5  yo children
* 55-60 yo males
* Asymptomatic
* Back pain
* Minority of cases bone pain, swelling, and pathological fractures
* Pathological fracture
* Palpable vertebral mass


* Painless, firm, swelling located at the anterior tibia
* Anterior bowing of the tibia


* Discrete, solitary mass male 55 years
* Pain at the site of the skeletal lesion
* Bone destruction


* Well-circumscribed lesion
* Well-defined, “punched-out” lytic lesions
* Intracortical osteolysis
* Marked erosion, expansion, and destruction of bone cortex
* Sclerotic band (osteoblastic rimming)
* Thick ridging around the periphery
* Cortical expansion
* “Soap bubble” appearance
* Homogeneous lesion matrix
 
 
* Fibrous proliferation of polyhedral, round, or spindle cells
* Calcifications
* Myxamatous matrix
* Psammomatoid growth patterns

Latest revision as of 20:27, 24 November 2015

  • 55-60 yo males
  • Back pain
  • Pathological fracture
  • Palpable vertebral mass


  • Discrete, solitary mass male 55 years
  • Pain at the site of the skeletal lesion
  • Bone destruction
  • Well-defined, “punched-out” lytic lesions
  • Marked erosion, expansion, and destruction of bone cortex
  • Thick ridging around the periphery
  • “Soap bubble” appearance
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