Sandbox: Bone DDx: Difference between revisions

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* 20-30 yo males
* 55-60 yo males
* Gradual, dull, and achy pain
* Back pain
* Pathological fracture
* Palpable vertebral mass


* Neurological deficit (cord compression)
* Scoliosis and torticollis


* Mainly located in the spine
* Discrete, solitary mass male 55 years
* Pain at the site of the skeletal lesion
* Bone destruction


* Expansile lytic lesions with a rim of reactive sclerosis
* Well-defined, “punched-out” lytic lesions
* Internal calcification
* Marked erosion, expansion, and destruction of bone cortex
* Cortical destruction, surrounding sclerosis, and periostitis
* Thick ridging around the periphery
* Secondary aneurysmal bone cyst
* “Soap bubble” appearance
 
 
* Trabeculae of woven and osteoid bones
* Surrounded by a single layer of osteoblasts
* Multiple osteoclasts
* Loose fibrovascular stroma
* Intralesional hemorrhage

Latest revision as of 20:27, 24 November 2015

  • 55-60 yo males
  • Back pain
  • Pathological fracture
  • Palpable vertebral mass


  • Discrete, solitary mass male 55 years
  • Pain at the site of the skeletal lesion
  • Bone destruction
  • Well-defined, “punched-out” lytic lesions
  • Marked erosion, expansion, and destruction of bone cortex
  • Thick ridging around the periphery
  • “Soap bubble” appearance
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