Sandbox: Bone DDx: Difference between revisions

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* 55-60 yo males
* Back pain
* Pathological fracture
* Palpable vertebral mass


* 10-20 yo males
* Bone pain and swelling
* Pathologic fracture
* History of Paget disease of bone or irradiation


* Discrete, solitary mass male 55 years
* Pain at the site of the skeletal lesion
* Bone destruction


 
* Well-defined, “punched-out” lytic lesions
* Hemorrhage, fibrosis and cystic degeneration
* Marked erosion, expansion, and destruction of bone cortex
* Areas of bone formation
* Thick ridging around the periphery
* Poorly formed trabecular bone
* “Soap bubble” appearance
* cellular pleomorphism and mitoses
 
 
* Metaphyseal regions of femur and tibia
* Medullary and cortical bone destruction
* Wide zone of transition with a moth-eaten appearance
* Sunburst and codman triangle
* Tumor matrix ossification/calcification

Latest revision as of 20:27, 24 November 2015

  • 55-60 yo males
  • Back pain
  • Pathological fracture
  • Palpable vertebral mass


  • Discrete, solitary mass male 55 years
  • Pain at the site of the skeletal lesion
  • Bone destruction
  • Well-defined, “punched-out” lytic lesions
  • Marked erosion, expansion, and destruction of bone cortex
  • Thick ridging around the periphery
  • “Soap bubble” appearance
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