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'''For patient information, click [[Essential thrombocytosis (patient information)|here]]'''
__NOTOC__
'''For patient information click [[{{PAGENAME}} (patient information)|here]]'''
{{Essential thrombocytosis}}
{{CMG}} {{AE}} {{STM}}


{{DiseaseDisorder infobox |
{{SK}} Essential thrombocythemia, primary thrombocythemia, congenital essential thrombocytosis, congenital essential thrombocythaemia, hereditary essential thrombocytosis, familial essential thrombocytosis, Epstein-Goedel syndrome, Hemorrhagic thrombocytosis, ET
  Name          = Essential thrombocytosis |
  ICD10          = {{ICD10|D|75|2|d|70}}, {{ICD10|D|47|3|d|37}} |
  ICD9          = {{ICD9|289.9}} |
  ICDO          = 9962/3 |
  Image          = |
  Caption        = |
  OMIM          = 187950 |
  DiseasesDB    = 4522 |
  MedlinePlus    = 000543 |
  eMedicineSubj  = |
  eMedicineTopic = |
  MeshID        = D013920 |
}}
{{Essential thrombocytosis}}
{{CMG}}


{{SK}} Essential thrombocythemia, primary thrombocythemia,  inherited essential thrombocythemia, inherited Essential thrombocytosis, inherited essential thrombocythemia, inherited ET, congenital essential thrombocytosis, congenital essential thrombocythaemia, congenital essential thrombocythemia, congenital ET, hereditary essential thrombocytosis, hereditary essential thrombocythaemia, hereditary essential thrombocythemia, hereditary ET, familial essential thrombocythemia, familial essential thrombocytosis, familial essential thrombocythaemia, familial ET, Epstein-Goedel syndrome
==[[Essential thrombocytosis overview|Overview]]==


==[[Essential thrombocytosis overview|Overview]]=='''Essential thrombocytosis''' '''(ET)''' is a rare hematologic disorder characterized by overproduction of platelets in the absence of an underlying disease.Platelets are responsible for hemostasis that is to control bleeding by forming plugs at the site of injury. Though overproduced, the platelets in ET are usually dysfunctional resulting in the vascular complications.
==[[Essential thrombocytosis historical perspective|Historical Perspective]]==
==[[Essential thrombocytosis historical perspective|Historical Perspective]]==
The disease, also called as Epstein-Goedel syndrome was first described by pathologists Emil Epstein and Alfred Goedel in the year 1934.


==[[Essential thrombocytosis classification|Classification]]==
==[[Essential thrombocytosis classification|Classification]]==
Essential or primary thrombocytosis as the name suggests does not have an underlying cause. But, rarely a familial form of the disease is inherited in an autosomal dominant fashion.


==[[Essential thrombocytosis pathophysiology|Pathophysiology]]==
==[[Essential thrombocytosis pathophysiology|Pathophysiology]]==


==[[Essential thrombocytosis epidemiology and demographics|Epidemiology & Demographics]]==
==[[Essential thrombocytosis epidemiology and demographics|Epidemiology and Demographics]]==
ET is a rare idiopathic condition affecting about 24 per every million people in the world. <ref>Essential thrombocythemia. http://ghr.nlm.nih.gov/condition/essential-thrombocythemia. Accessed onOctober 29, 2015</ref>


==[[Essential thrombocytosis epidemiology and demographics|Risk Factors]]==
==[[Essential thrombocytosis epidemiology and demographics|Risk Factors]]==
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==[[Essential thrombocytosis differential diagnosis|Differentiating Essential thrombocytosis from other Diseases]]==
==[[Essential thrombocytosis differential diagnosis|Differentiating Essential thrombocytosis from other Diseases]]==


==[[Essential thrombocytosis natural history|Natural History, Complications & Prognosis]]==
==[[Essential thrombocytosis natural history, complications and prognosis|Natural History, Complications and Prognosis]]==


==Diagnosis==
==Diagnosis==
[[Essential thrombocytosis history and symptoms|History & Symptoms]] | [[Essential thrombocytosis physical examination|Physical Examination]] | [[Essential thrombocytosis staging|Staging]] | [[Essential thrombocytosis laboratory tests|Lab Tests]] | [[Essential thrombocytosis electrocardiogram|Electrocardiogram]] | [[Essential thrombocytosis chest x ray|Chest X Ray]] | [[Essential thrombocytosis CT|CT]] | [[Essential thrombocytosis MRI|MRI]] | [[Essential thrombocytosis echocardiography or ultrasound|Echocardiography or Ultrasound]] | [[Essential thrombocytosis other imaging findings|Other Imaging Findings]] | [[Essential thrombocytosis other diagnostic studies|Other Diagnostic Studies]] | [[Essential thrombocytosis laboratory tests#Diagnostic criteria|Diagnostic criteria]]
[[Essential thrombocytosis diagnostic criteria|Diagnostic Criteria]] | [[Essential thrombocytosis history and symptoms|History and Symptoms]] | [[Essential thrombocytosis physical examination|Physical Examination]] | [[Essential thrombocytosis laboratory findings|Laboratory Findings]] | [[Essential thrombocytosis electrocardiogram|Electrocardiogram]] | [[Essential thrombocytosis chest x ray|Chest X Ray]] | [[Essential thrombocytosis CT|CT]] | [[Essential thrombocytosis MRI|MRI]] | [[Essential thrombocytosis echocardiography or ultrasound|Echocardiography or Ultrasound]] | [[Essential thrombocytosis other imaging findings|Other Imaging Findings]] | [[Essential thrombocytosis other diagnostic studies|Other Diagnostic Studies]]


==Treatment==
==Treatment==
[[Essential thrombocytosis medical therapy#Medical therapy|Medical Therapy]] | [[Essential thrombocytosis medical therapy#Special care related to pregnancy|Special care related to pregnancy]] | [[Essential thrombocytosis surgery|Surgery]] | [[Essential thrombocytosis primary prevention|Primary Prevention]] | [[Essential thrombocytosis secondary prevention|Secondary Prevention]]
[[Essential thrombocytosis medical therapy#Medical therapy|Medical Therapy]] | [[Essential thrombocytosis surgery|Surgery]] | [[Essential thrombocytosis primary prevention|Primary Prevention]] | [[Essential thrombocytosis secondary prevention|Secondary Prevention]] | [[Essential thrombocytosis cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] |  [[Essential thrombocytosis future or investigational therapies|Future or Investigational Therapies]]


==Resources==
==Resources==
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{{Hematology}}
{{Hematology}}
{{Hematological malignancy histology}}
{{Hematological malignancy histology}}
[[de:Essentielle Thrombozythämie]]
[[fr:Thrombocytémie essentielle]]
[[pl:Nadpłytkowość samoistna]]


[[Category:Disease]]
[[Category:Disease]]

Latest revision as of 13:49, 23 December 2015

For patient information click here

Essential thrombocytosis Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Epidemiology and Demographics

Risk Factors

Screening

Causes

Differentiating Essential thrombocytosis from other Diseases

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Criteria

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

Chest X Ray

CT

MRI

Echocardiography or Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Essential thrombocytosis On the Web

Most recent articles

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Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Essential thrombocytosis

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X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Essential thrombocytosis

CDC on Essential thrombocytosis

Essential thrombocytosis in the news

Blogs on Essential thrombocytosis

Directions to Hospitals Treating Essential thrombocytosis

Risk calculators and risk factors for Essential thrombocytosis

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Soujanya Thummathati, MBBS [2]

Synonyms and keywords: Essential thrombocythemia, primary thrombocythemia, congenital essential thrombocytosis, congenital essential thrombocythaemia, hereditary essential thrombocytosis, familial essential thrombocytosis, Epstein-Goedel syndrome, Hemorrhagic thrombocytosis, ET

Overview

Historical Perspective

Classification

Pathophysiology

Epidemiology and Demographics

Risk Factors

Screening

Causes

Differentiating Essential thrombocytosis from other Diseases

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Criteria | History and Symptoms | Physical Examination | Laboratory Findings | Electrocardiogram | Chest X Ray | CT | MRI | Echocardiography or Ultrasound | Other Imaging Findings | Other Diagnostic Studies

Treatment

Medical Therapy | Surgery | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

Resources

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Template:WikiDoc Sources

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