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CMEUser, nocaptcha, nukepages, Administrators
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Maria Villarreal (talk | contribs)
CMEUser, nocaptcha, nukepages, Administrators
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{| style="border: 0px; font-size: 90%; margin: 3px; width: 800px" align=center
|valign=top|
|+
!style="padding: 0 5px; background: #DCDCDC" colspan=4|{{fontcolor|#000| Secondary bone tumors: classification <br> <SMALL> Adapted from Greenspan A et al. 2006 <ref name="greenspan">Greenspan A, Jundt G, Remagen W. Differential diagnosis in orthopaedic oncology. Philadelphia : Lippincott Williams & Wilkins, c2007. (2006) ISBN:0781779308</ref></SMALL>}}
|-
!style="background: #4479BA; width: 200px;" colspan="2"|{{fontcolor|#FFF|Tumor matrix}}
!style="background: #4479BA; width: 200px;" colspan="2"|{{fontcolor|#FFF|Tumor location}}
|-
|style="padding: 0 5px; background: #DCDCDC" | '''Osteolytic'''
|
*Renal cell cancer
*Melanoma
*Multiple myeloma
*Non-small cell lung cancer
*Thyroid cancer
*Non-Hodgkin lymphoma
*Langerhans cell histiocytosis
|style="padding: 0 5px; background: #DCDCDC" | '''Skull'''
|
*Breast cancer   
*Lung cancer   
*Melanoma   
*Prostate cancer 
*Thyroid cancer (usually follicular)
*Renal cell cancer   
*Lymphoma   
*Leukaemia   
*Multiple myeloma
|-
|style="padding: 0 5px; background: #DCDCDC" |'''Osteoblastic'''
|
*Prostate cancer
*Carcinoid syndrome
*Small cell lung cancer
*Hodgkin lymphoma
*Medulloblastoma
|style="padding: 0 5px; background: #DCDCDC"| '''Vertebral'''
|
*Breast cancer   
*Lung cancer
*Prostate cancer   
*Lymphoma   
*Renal cell carcinoma
*Gastrointestinal tract malignancies
* Melanoma
|-
|style="padding: 0 5px; background: #DCDCDC" | '''Mixed'''
|
*Breast cancer
*Gastrointestinal cancers
*Squamous cancers (at most primary sites)
|style="padding: 0 5px; background: #DCDCDC" rowspan="2" | '''Distal appendicular'''
| rowspan="2" |
*Lung cancer
*Breast cancer
*Renal cell cancer
*Prostate cancer
|-
|style="padding: 0 5px; background: #DCDCDC"| '''Other types ( "Blow out" and "Cookie type")'''
|
*Renal cell carcinoma   
*Thyroid cancer
*Hepatocellular carinoma   
*Bronchogenic carcinoma
|}


{| style="border: 0px; font-size: 90%; margin: 3px; width: 800px" align=center
{| style="border: 0px; font-size: 90%; margin: 3px; width: 800px" align=center
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*Metastases
*Metastases
|-
|-
|}
{| class="wikitable"
! colspan="3" style="text-align: center; font-weight: bold;" | Bone or cartilage mass classification
<SMALL>Adapted from ICD-10/WHO (9180–9269)<br><ref name="pmid18223119">{{cite journal |vauthors=Miller TT |title=Bone tumors and tumorlike conditions: analysis with conventional radiography |journal=Radiology |volume=246 |issue=3 |pages=662–74 |year=2008 |pmid=18223119 |doi=10.1148/radiol.2463061038 |url=}}</ref></SMALL>
|-
| style="text-align: center;" | '''Location'''
| style="text-align: center;" | '''Origin'''
| style="text-align: center;" | '''Type of tumor'''
|-
| rowspan="3" style="text-align: center;" | '''Diaphysis'''
| Myeloid
| Multiple myeloma
|-
| Epithelial
| Adamantinoma
|-
| PNET/Ewing family
| Ewing's sarcoma
|-
| rowspan="10" style="text-align: center;" | '''Metaphysis'''
| rowspan="3" | Osteoblast
| Osteoid osteoma
|-
| Osteoblastoma
|-
| Osteoma/osteosarcoma
|-
| rowspan="5" | Chondroblast
| Chondroma/ecchondroma/enchondroma
|-
| Enchondromatosis
|-
| Chondrosarcoma
|-
| Osteochondroma
|-
| Chondromyxoid fibroma
|-
| rowspan="2" | Fibrous
| Ossifying fibroma
|-
| Fibrosarcoma
|-
| rowspan="2" style="text-align: center;" | '''Epiphysis'''
| Chondroblast
| Chondroblastoma
|-
| Myeloid
| Giant-cell tumor of bone
|-
| style="text-align: center;" | '''Other/ungrouped'''
| Notochord
| Chordoma
|}
|}

Latest revision as of 20:57, 11 February 2016
Secondary bone tumors: classification
Adapted from Greenspan A et al. 2006 [1]
Tumor matrix Tumor location
Osteolytic
  • Renal cell cancer
  • Melanoma
  • Multiple myeloma
  • Non-small cell lung cancer
  • Thyroid cancer
  • Non-Hodgkin lymphoma
  • Langerhans cell histiocytosis
 Skull
  • Breast cancer
  • Lung cancer
  • Melanoma
  • Prostate cancer
  • Thyroid cancer (usually follicular)
  • Renal cell cancer
  • Lymphoma
  • Leukaemia
  • Multiple myeloma
Osteoblastic
  • Prostate cancer
  • Carcinoid syndrome
  • Small cell lung cancer
  • Hodgkin lymphoma
  • Medulloblastoma
 Vertebral
  • Breast cancer
  • Lung cancer
  • Prostate cancer
  • Lymphoma
  • Renal cell carcinoma
  • Gastrointestinal tract malignancies
  • Melanoma
Mixed
  • Breast cancer
  • Gastrointestinal cancers
  • Squamous cancers (at most primary sites)
 Distal appendicular
  • Lung cancer
  • Breast cancer
  • Renal cell cancer
  • Prostate cancer
Other types ( "Blow out" and "Cookie type")
  • Renal cell carcinoma
  • Thyroid cancer
  • Hepatocellular carinoma
  • Bronchogenic carcinoma
Bone or cartilage mass classification
Adapted from ICD-10/WHO (9180–9269)[2]
Osteogenic tumors: bone-forming tumors Cartilage tumors: cartilage-forming tumors Fibrogenic tumors Cystic tumors Others ( hematopoietic, notochordal, neuroectodermal)
Histological Type
  • Osteoid osteoma
  • Osteoblastoma
  • Osteoma
  • Osteosarcoma
  • Osteochondroma
  • Chondroblastoma
  • Enchondroma
  • Chondromyxoid fibroma
  • Desmoplastic fibroma
  • Fibrous dysplasia
  • Ossyifing fibroma
  • Non-ossifying fibroma
  • Unicameral bone cyst
  • Aneurysmal bone cyst
  • Giant cell tumor
  • Adamantimoma
  • Eosinophilic granuloma
  • Ewing sarcoma
  • Metastases
Epiphysis Diaphysis Metaphysis
Tumor Location
  • Chondroblastoma
  • Giant cell tumor
  • Intraosseous ganglion
  • Chondrosarcoma
  • Metastases
  • Ewing's sarcoma
  • Eosinophilic granuloma
  • Ewing sarcoma
  • Myeloma
  • Metastases
  • Adamantimoma
  • Ossyfing fibroma
  • Enchondroma
  • Osteosarcoma
  • Chondromyxoid fibroma
  • Unicameral bone cyst
  • Osteoid osteoma
  • Metastases
Benign Malignant
Tumor Nature
  • Osteoid osteoma
  • Enchondroma
  • Chondromyxoid fibroma
  • Ossifying fibroma
  • Osteoblastoma
  • Unicameral bone cyst
  • Aneursymal bone cyst
  • Giant cell tumor
  • Osteochondroma
  • Osteosarcoma
  • Ewing sarcoma
  • Chondrosarcoma
  • Fibrosarcoma
  • Malignant fibrous histiocytoma
  • Plasma cell myeloma
  • Metastases



Bone or cartilage mass classification

Adapted from ICD-10/WHO (9180–9269)
[2]

Location Origin Type of tumor
Diaphysis Myeloid Multiple myeloma
Epithelial Adamantinoma
PNET/Ewing family Ewing's sarcoma
Metaphysis Osteoblast Osteoid osteoma
Osteoblastoma
Osteoma/osteosarcoma
Chondroblast Chondroma/ecchondroma/enchondroma
Enchondromatosis
Chondrosarcoma
Osteochondroma
Chondromyxoid fibroma
Fibrous Ossifying fibroma
Fibrosarcoma
Epiphysis Chondroblast Chondroblastoma
Myeloid Giant-cell tumor of bone
Other/ungrouped Notochord Chordoma
  1. ↑ Greenspan A, Jundt G, Remagen W. Differential diagnosis in orthopaedic oncology. Philadelphia : Lippincott Williams & Wilkins, c2007. (2006) ISBN:0781779308
  2. ↑ 2.0 2.1 Miller TT (2008). "Bone tumors and tumorlike conditions: analysis with conventional radiography". Radiology. 246 (3): 662–74. doi:10.1148/radiol.2463061038. PMID 18223119.
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