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__NOTOC__
{{Atrial septal defect}}
{{Atrial septal defect}}
{{CMG}}; '''Associate Editors-In-Chief:''' [[Priyamvada Singh|Priyamvada Singh, M.B.B.S.]] [mailto:psingh@perfuse.org], {{CZ}}; '''Assistant Editor-In-Chief:''' [[Kristin Feeney|Kristin Feeney, B.S.]] [mailto:kfeeney@perfuse.org]
{{CMG}}; '''Associate Editor(s)-In-Chief:''' [[Priyamvada Singh|Priyamvada Singh, M.B.B.S.]] [mailto:psingh13579@gmail.com], {{CZ}}; '''Assistant Editor(s)-In-Chief:''' [[Kristin Feeney|Kristin Feeney, B.S.]] [mailto:kfeeney@elon.edu]
 
'''For a full discussion on the usage of echocardiography for atrial septal defect diagnosis click [[atrial septal defect echocardiography|here]].'''


==Overview==
==Overview==
Echocardiography is the preferred diagnostic tool in the evaluation of an atrial septal defect. A range of techniques may be employed to definitively image and diagnose the nature of an atrial septal defect. These include: a sub-costal four chamber view, doppler echocardiography, contrast echocardiogrpahy, and transesophageal echocardiography.
Echocardiography is the preferred diagnostic tool in the evaluation of an atrial septal defect. A range of techniques may be employed to definitively image and diagnose the nature of an atrial septal defect. These include modalities such as: M-mode, trans-thoracic, trans-esophageal, contrast, and Doppler.


==Echocardiography Techniques for ASD==
==Echocardiography==
A range of echocardiography techniques can be used to visualize and diagnose a suspected atrial septal defect. Each technique offers additional imaging information to support an atrial septal defect diagnosis.
A range of echocardiography techniques can be used to visualize and diagnose a suspected atrial septal defect. Each technique offers additional imaging information to support an atrial septal defect diagnosis.


==M-mode==
===M-mode===
* Effective modality for imaging moderate to large ostium secundum atrial septal defects
* Effective modality for imaging moderate to large ostium secundum atrial septal defects
:* Provides imaging of:
:* Provides imaging of:
::* Right ventricular enlargement
::* Right ventricular enlargement
::* Paradoxical motion involving the interventricular septum
::* Paradoxical motion involving the interventricular septum
:*Note: imaging in M-mode modality can be indicative of [[right ventricular overload]]. It is not substantial enough alone to make a full diagnosis of a suspected atrial septal defect.
==Trans-thoracic echocardiography==
* Effective two-dimensional modality for visualizing an ostium secundum atrial septal defect.
* Types:
:* Apical four chamber view
:* Subcoastal four chamber view
* Provides imaging of:
:* Right ventricular enlargement
:* Paradoxical motion involving the ventricular septum
:* Right atrium enlargement
===Advantages===
*Determines which type of defect exists.
*Necessary to evaluate for anomalous pulmonary veins.
*Evaluates for an atrial septal aneurysm.


===Disadvantages===
===Disadvantages===
* Apical four chamber view involves a parallel angle of the echocardiographic beams onto the atrial septum causing artifact in the echo
* M-mode modality can appear indicative of [[right ventricular overload]]. It is not substantial enough alone to make a full diagnosis of a suspected atrial septal defect.
* Subcostal four chamber view can be ineffective in overweight/obese patients.
* Size of the defect seen in a TTE does not parallel the measurement of shunt flow from cardiac catheterization.


===Sensitivity===
===[[Atrial septal defect transthoracic echocardiography|Trans-thoracic echocardiography (TTE)]]===
* One study found that subcostal approach could successfully visualize the majority of ostium primum and ostium secundum atrial septal defects.<ref name="pmid6853907">{{cite journal| author=Shub C, Dimopoulos IN, Seward JB, Callahan JA, Tancredi RG, Schattenberg TT et al.| title=Sensitivity of two-dimensional echocardiography in the direct visualization of atrial septal defect utilizing the subcostal approach: experience with 154 patients. | journal=J Am Coll Cardiol | year= 1983 | volume= 2 | issue= 1 | pages= 127-35 | pmid=6853907 | doi= | pmc= | url= }} </ref>
* Visualization of sinus venosus atrial septal defect is less successful, less than 50% of the cases were properly imaged.<ref name="pmid6853907">{{cite journal| author=Shub C, Dimopoulos IN, Seward JB, Callahan JA, Tancredi RG, Schattenberg TT et al.| title=Sensitivity of two-dimensional echocardiography in the direct visualization of atrial septal defect utilizing the subcostal approach: experience with 154 patients. | journal=J Am Coll Cardiol | year= 1983 | volume= 2 | issue= 1 | pages= 127-35 | pmid=6853907 | doi= | pmc= | url= }} </ref>


==[[Atrial septal defect transesophageal echocardiography|Trans-esophageal echocardiography (TEE)]]==
===[[Atrial septal defect transesophageal echocardiography|Trans-esophageal echocardiography (TEE)]]===


==Contrast echocardiography==
===[[Atrial septal defect contrast echocardiography|Contrast echocardiography]]===
* Used to determine the presence of intercardiac shunting often seen in the apical four chamber view
* Agitated saline is commonly used as the contrast material.
:* Injected into a peripheral [[vein]] during [[echocardiography]], small air bubbles can be seen on the imaging.
:* It may be possible to see bubbles travel across an atrial septal defect either at rest or during a cough.
:* Bubbles will only flow from [[right atrium]] to [[left atrium]] if the RA pressure is greater than LA


===Common Findings===
===Doppler===
* A right-to-left interatrial shunt can be seen:
:* When an atrial septal defect with accompanying pulmonary hypertension, resulting in a left-to-right reversal.
:* Any time a patent foramen ovale defect is present.
:* When an uncomplicated atrial septal defect has an imbalance in right-sided pressure, such as from coughing or the Valsalva maneuver.
:* When an uncomplicated atrial septal defect has a momentary onset of left ventricular contraction.
 
===Sensitivity===
* Not recommended for:
:* Left-to-right interatrial shunt diagnosis
:* Pregnant patients
:* Patients with severe pulmonary hypertension
 
==Disadvantages==
* False positives in the setting of a pulmonary arteriovenous malformation.
* Difficulty in quantifying the size of the shunt
 
==Doppler==
* Used to demonstrate left to right flow.
* Used to demonstrate left to right flow.
* Effective modality for:
* Effective modality for:
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:* Determination of high velocity flow, useful in patients with restrictive defects, obstructed pulmonary venous return and/or left atrial hypertension
:* Determination of high velocity flow, useful in patients with restrictive defects, obstructed pulmonary venous return and/or left atrial hypertension


===Disadvantages===
====Disadvantages====
* May show false positive shunting as caval flow and incorrectly set gain may appear as left to right flow.
* May show false positive shunting as caval flow and incorrectly set gain may appear as left to right flow.
* Coloring across the interatrial septum can distort the perception of the shunt flow
* Coloring across the interatrial septum can distort the perception of the shunt flow
* Not effective in determination of sinus venosus defects
* Not effective in determination of sinus venosus defects


===ACC / AHA 2008 Guidelines - Evaluation of the Unoperated Patient - Atrial Septal Defect (DO NOT EDIT)<ref name="pmid19038677">{{cite journal| author=Warnes CA, Williams RG, Bashore TM, Child JS, Connolly HM, Dearani JA et al.| title=ACC/AHA 2008 guidelines for the management of adults with congenital heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Develop Guidelines on the Management of Adults With Congenital Heart Disease). Developed in Collaboration With the American Society of Echocardiography, Heart Rhythm Society, International Society for Adult Congenital Heart Disease, Society for Cardiovascular Angiography and Interventions, and Society of Thoracic Surgeons. | journal=J Am Coll Cardiol | year= 2008 | volume= 52 | issue= 23 | pages= e1-121 | pmid=19038677 | doi=10.1016/j.jacc.2008.10.001 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19038677  }} </ref>===


{| class="wikitable"
|-
| colspan="1" style="text-align:center; background:LightGreen"|[[ACC AHA guidelines classification scheme#Classification of Recommendations|Class I]]
|-
| bgcolor="LightGreen"|<nowiki>"</nowiki>'''1.''' ASD should be diagnosed by imaging techniques with demonstration of shunting across the defect and evidence of RV volume overload and any associated anomalies. ([[ACC AHA guidelines classification scheme#Level of Evidence|Level of Evidence: C]]) <nowiki>"</nowiki>
|}


==References==
==References==
{{reflist|2}}
{{reflist|2}}
{{WH}}
{{WS}}
[[CME Category::Cardiology]]


[[Category:Cardiology]]
[[Category:Cardiology]]
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[[Category:Pediatrics]]
[[Category:Pediatrics]]
[[Category:Mature chapter]]
[[Category:Mature chapter]]
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Latest revision as of 01:50, 15 March 2016

Atrial Septal Defect Microchapters

Home

Patient Information

Overview

Anatomy

Classification

Ostium Secundum Atrial Septal Defect
Ostium Primum Atrial Septal Defect
Sinus Venosus Atrial Septal Defect
Coronary Sinus
Patent Foramen Ovale
Common or Single Atrium

Pathophysiology

Epidemiology and Demographics

Risk Factors

Natural History and Prognosis

Complications

Diagnosis

History and Symptoms

Physical Examination

Electrocardiogram

Chest X Ray

CT

MRI

Echocardiography

Transesophageal Echocardiography
Transthoracic Echocardiography
Contrast Echocardiography
M-Mode
Doppler

Transcranial Doppler Ultrasound

Cardiac Catheterization

Exercise Testing

ACC/AHA Guidelines for Evaluation of Unoperated Patients

Treatment

Medical Therapy

Surgery

Indications for Surgical Repair
Surgical Closure
Minimally Invasive Repair


Robotic ASD Repair
Percutaneous Closure
Post-Surgical Follow Up

Special Scenarios

Pregnancy
Diving and Decompression Sickness
Paradoxical Emboli
Pulmonary Hypertension
Eisenmenger's Syndrome
Atmospheric Pressure

Case Studies

Case #1

Atrial septal defect echocardiography modalities On the Web

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Priyamvada Singh, M.B.B.S. [2], Cafer Zorkun, M.D., Ph.D. [3]; Assistant Editor(s)-In-Chief: Kristin Feeney, B.S. [4]

For a full discussion on the usage of echocardiography for atrial septal defect diagnosis click here.

Overview

Echocardiography is the preferred diagnostic tool in the evaluation of an atrial septal defect. A range of techniques may be employed to definitively image and diagnose the nature of an atrial septal defect. These include modalities such as: M-mode, trans-thoracic, trans-esophageal, contrast, and Doppler.

Echocardiography

A range of echocardiography techniques can be used to visualize and diagnose a suspected atrial septal defect. Each technique offers additional imaging information to support an atrial septal defect diagnosis.

M-mode

  • Effective modality for imaging moderate to large ostium secundum atrial septal defects
  • Provides imaging of:
  • Right ventricular enlargement
  • Paradoxical motion involving the interventricular septum

Disadvantages

  • M-mode modality can appear indicative of right ventricular overload. It is not substantial enough alone to make a full diagnosis of a suspected atrial septal defect.

Trans-thoracic echocardiography (TTE)

Trans-esophageal echocardiography (TEE)

Contrast echocardiography

Doppler

  • Used to demonstrate left to right flow.
  • Effective modality for:
  • Confirmation of a suspected atrial septal defect
  • Estimation of the defect size
  • Determination of the universal direction of flow across the septum
  • Determination of the usage of percutaneous closure and surgical therapies
  • Determination of high velocity flow, useful in patients with restrictive defects, obstructed pulmonary venous return and/or left atrial hypertension

Disadvantages

  • May show false positive shunting as caval flow and incorrectly set gain may appear as left to right flow.
  • Coloring across the interatrial septum can distort the perception of the shunt flow
  • Not effective in determination of sinus venosus defects

ACC / AHA 2008 Guidelines - Evaluation of the Unoperated Patient - Atrial Septal Defect (DO NOT EDIT)[1]

Class I
"1. ASD should be diagnosed by imaging techniques with demonstration of shunting across the defect and evidence of RV volume overload and any associated anomalies. (Level of Evidence: C) "

References

  1. Warnes CA, Williams RG, Bashore TM, Child JS, Connolly HM, Dearani JA; et al. (2008). "ACC/AHA 2008 guidelines for the management of adults with congenital heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Develop Guidelines on the Management of Adults With Congenital Heart Disease). Developed in Collaboration With the American Society of Echocardiography, Heart Rhythm Society, International Society for Adult Congenital Heart Disease, Society for Cardiovascular Angiography and Interventions, and Society of Thoracic Surgeons". J Am Coll Cardiol. 52 (23): e1–121. doi:10.1016/j.jacc.2008.10.001. PMID 19038677.

Template:WH Template:WS CME Category::Cardiology