Vasculitis laboratory findings: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Vasculitis}} | {{Vasculitis}} | ||
{{CMG}}; {{AE}} {{MUT}} | |||
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==Overview== | ==Overview== | ||
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==Laboratory Findings== | ==Laboratory Findings== | ||
Basic lab tests may include a | Basic lab tests may include a | ||
* [[CBC]] | * [[CBC]] - [[leukocytosis]], [[eosinophilia]] > 10% | ||
* Chem-7 (look for creatinine) | * Chem-7 (look for creatinine) - Elevated serum [[BUN]] (> 40 mg/dL) or serum [[creatinine]] (> 1.5 mg/dL) | ||
* Muscle enzyme | * Muscle enzyme | ||
* [[Liver function tests]] | * [[Liver function tests]] | ||
* [[ESR]] | * [[ESR]] - elevated [[ESR]] ≥ 50 mm/hour Westergren in [[temporal arteritis]] | ||
* Hepatitis seroloties | * Hepatitis seroloties | ||
* [[Urinalysis]] | * [[Urinalysis]] - microscopic hematuria or RBC casts in [[Wegener's granulomatosis]] | ||
Additional, more specific tests include: | Additional, more specific tests include: | ||
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==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
[[Category:Rheumatology]] | |||
{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} |
Latest revision as of 17:41, 20 June 2016
Vasculitis |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: M.Umer Tariq [2]
Overview
Laboratory Findings
Basic lab tests may include a
- CBC - leukocytosis, eosinophilia > 10%
- Chem-7 (look for creatinine) - Elevated serum BUN (> 40 mg/dL) or serum creatinine (> 1.5 mg/dL)
- Muscle enzyme
- Liver function tests
- ESR - elevated ESR ≥ 50 mm/hour Westergren in temporal arteritis
- Hepatitis seroloties
- Urinalysis - microscopic hematuria or RBC casts in Wegener's granulomatosis
Additional, more specific tests include:
- Antinuclear antibody (ANA) test can detect an underlying connective tissue disorder, especially SLE
- Complement levels that are low can suggest mixed cryoglobulinemia, hepatitis C infection, and SLE, but not most other vasculitides.
- Antineutrophil cytoplasmic antibody (ANCA) may highly suggest Wegener's granulomatosis, microscopic polyangiitis, Churg-Strauss syndrome, or drug-induced vasculitis, but is not diagnostic.