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| __NOTOC__ | | __NOTOC__ |
| {{Drug induced liver injury}} | | {{Drug induced liver injury}} |
| {{CMG}} {{AE}} | | {{CMG}}; {{AE}} {{Rachita}} |
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| ==Overview== | | ==Overview== |
| | Hundreds of prescription and nonprescription medications as well as supplements have been implicated in drug induced liver injury. A free searchable database of causative agents is available through the [https://livertox.nlm.nih.gov/ National Institute of Health]. |
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| ==Causes== | | ==Causes== |
| ===Common Causes=== | | ===Common Causative Agents:=== |
| *[[Acetaminophen]] | | *[[Acetaminophen]] |
| *[[Azithromycin]] | | *[[Azithromycin]] |
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| ==References== | | ==References== |
| {{Reflist|2}} | | {{Reflist|2}} |
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| [[Category:Hepatology]]
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Rachita Navara, M.D. [2]
Overview
Hundreds of prescription and nonprescription medications as well as supplements have been implicated in drug induced liver injury. A free searchable database of causative agents is available through the National Institute of Health.
Causes
Common Causative Agents:
Causes by Organ System
| Cardiovascular
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No underlying causes
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| Chemical / poisoning
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No underlying causes
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| Dermatologic
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No underlying causes
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| Drug Side Effect
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5-Azacytidine, Abacavir, Abiraterone, Acetaminophen, Agomelatine, Albendazole, Allopurinol, Altretamine, Amineptine, Amiodarone, Amitriptyline, Amoxicillin, Amphotericin B, Amprenavir, Anabolic steroids, Antituberculosis drugs, Apixaban, Arsenic trioxide, Asafetida, Asparaginase, Atorvastatin, Atovaquone, Azathioprine, Benoxaprofen, Bexarotene, Black cohosh extract, Bosentan, Bosutinib, Bromfenac, Bumetanide, Carfilzomib, Cascara, Caspofungin, Chaparral, Chenodeoxycholic acid, Chlormezanone, Chlorzoxazone, Ciprofloxacin, Clofarabine, Combined oral contraceptive pill, Comfrey, Crizotinib, Cyclobenzaprine, Dantrolene, Daptomycin, Dasatinib, Deferasirox, Desipramine, Diclofenac, Disulfiram, Docetaxel, Donepezil, Dothiepin, Dronedarone, Eltrombopag, Emtricitabine, Entecavir, Ephedra, Erlotinib, Erythromycin estolate, Ethanol, Ethinylestradiol, Ethionamide, Etretinate, Febuxostat, Felbamate, Fenofibrate, Fingolimod, Fluconazole, Flucytosine, Fluoxymesterone, Flutamide, Fluvastatin, Fosamprenavir, Frusemide, Fusidic acid, Ganciclovir, Gemcitabine, Gemtuzumab ozogamicin, Gold salts, Golimumab, Halothane, Imatinib mesylate, Imipenem, Interferon alpha, Interferon beta, Interleukin 2, Ipilimumab, Isoniazid, Isotretinoin, Kava root extract, Ketoconazole, Lapatinib ditosylate, Leflunomide, Lovastatin, Maraviroc, Meropenem, Mesalazine, Methotrexate, Methyldopa, Methyldopate, Micafungin, Minocycline, Mirtazapine, Mithramycin, Naltrexone, Nandrolone, Natalizumab, Nelfinavir, Nevirapine, Niacin, Nicotinic acid, Nimesulide, Nitisinone, Nitrofurantoin, Norfloxacin, Nortriptyline, Ondansetron, Oxyphenisatine, Paclitaxel, Para-amino salicylic acid, Pazopanib, Pegvisomant, Pemoline, Pentostatin, Phenelzine, Phenylbutazone, Phenytoin, Pralatrexate, Pravastatin, Procainamide, Propylthiouracil, Prothionamide, Pyrazinamide, Pyritinol, Pyrrolizidine alkaloids, Regorafenib, Rifabutin, Rifampicin, Riluzole, Ritonavir, Rivaroxaban, Rosuvastatin, Saquinavir, Simvastatin, Sitaxentan, Sorafenib, Stanozolol, Statins, Succimer, Suloctidil, Sulphasalazine, Sulphinpyrazone, Tegafur, Telithromycin, Teriflunomide, Thiabendazole, Thioguanine, Ticlopidine, Tipranavir, Tizanidine, Tolbutamide, Tolcapone, Tolrestat, Trabectedin, Troglitazone, Trovafloxacin, Ursodeoxycholic acid, Valganciclovir, Valproic acid, Velnacrine, Verapamil, Voriconazole, Ximelagatran, Zotepine, Alcohol, Carbimazole, Phenothiazines, Clofibrate, Tetracyclines
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| Ear Nose Throat
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No underlying causes
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| Endocrine
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No underlying causes
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| Environmental
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No underlying causes
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| Gastroenterologic
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No underlying causes
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| Genetic
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No underlying causes
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| Hematologic
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No underlying causes
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| Iatrogenic
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No underlying causes
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| Infectious Disease
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No underlying causes
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| Musculoskeletal / Ortho
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No underlying causes
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| Neurologic
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No underlying causes
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| Nutritional / Metabolic
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No underlying causes
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| Obstetric/Gynecologic
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No underlying causes
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| Oncologic
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No underlying causes
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| Opthalmologic
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No underlying causes
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| Overdose / Toxicity
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No underlying causes
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| Psychiatric
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No underlying causes
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| Pulmonary
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No underlying causes
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| Renal / Electrolyte
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No underlying causes
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| Rheum / Immune / Allergy
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No underlying causes
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| Sexual
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No underlying causes
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| Trauma
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No underlying causes
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| Urologic
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No underlying causes
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| Dental
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No underlying causes
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| Miscellaneous
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No underlying causes
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Causes in Alphabetical Order
References