Cryptococcus infection medical therapy: Difference between revisions

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==Overview==
==Overview==
==Medical Therapy==
===Antimicrobial Regimen===
*'''Cryptococcus Meningoencephalitis in Human Immunodeficiency Virus–Infected Individuals'''
**'''Induction Therapy'''
::*Preferred regimen (1): Amphotericin B deoxycholate (0.7–1.0 mg/kg per day) plus flucytosine (100 mg/kg per day) for 2 weeks {{AND}} Begin HAART 2–10 weeks after the start of initial antifungal treatment.
::*Preferred regimen (2):  Liposomal AmB (3–4 mg/kg per day) or ABLC (5 mg/kg per day, with renal function concerns) plus flucytosine (100 mg/kg per day) for 2 weeks {{AND}} Begin HAART 2–10 weeks after the start of initial antifungal treatment.
::*Preferred regimen (3): AmBd (0.7–1.0 mg/kg per day) or liposomal AmB (3–4 mg/kg per day) or ABLC (5 mg/kg per day, for flucytosine-intolerant patients)


==References==
==References==
{{Reflist|2}}
{{Reflist|2}}

Latest revision as of 15:27, 1 June 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

Medical Therapy

Antimicrobial Regimen

  • Cryptococcus Meningoencephalitis in Human Immunodeficiency Virus–Infected Individuals
    • Induction Therapy
  • Preferred regimen (1): Amphotericin B deoxycholate (0.7–1.0 mg/kg per day) plus flucytosine (100 mg/kg per day) for 2 weeks Template:AND Begin HAART 2–10 weeks after the start of initial antifungal treatment.
  • Preferred regimen (2): Liposomal AmB (3–4 mg/kg per day) or ABLC (5 mg/kg per day, with renal function concerns) plus flucytosine (100 mg/kg per day) for 2 weeks Template:AND Begin HAART 2–10 weeks after the start of initial antifungal treatment.
  • Preferred regimen (3): AmBd (0.7–1.0 mg/kg per day) or liposomal AmB (3–4 mg/kg per day) or ABLC (5 mg/kg per day, for flucytosine-intolerant patients)

References