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== Historical perspective ==
== Historical perspective ==
*In 1856, Dr. Maestre de San Juan was the first one to report a case combining small [[testes]] (hypogonadism) and [[Anosmia|loss of smelling]] sense in a patient.  
*In 1856, Dr. Maestre de San Juan was the first one to report a case combining small [[testes]] (hypogonadism) and [[Anosmia|loss of smelling]] sense in a patient.  
*In 1944, Dr. Kallmann was the first to identify it as a syndrome which was named on him after then. He held a study showing the correlation between anosmia and hypogonadism in different families.<ref name="pmid18985070">{{cite journal| author=Dodé C, Hardelin JP| title=Kallmann syndrome. | journal=Eur J Hum Genet | year= 2009 | volume= 17 | issue= 2 | pages= 139-46 | pmid=18985070 | doi=10.1038/ejhg.2008.206 | pmc=2986064 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18985070  }} </ref>
*In 1944, Dr. Kallmann was the first to identify a case combining hypogonadism and [[anosmia]] as a syndrome which was named on him after then. He held a study showing the correlation between anosmia and hypogonadism in different families.<ref name="pmid18985070">{{cite journal| author=Dodé C, Hardelin JP| title=Kallmann syndrome. | journal=Eur J Hum Genet | year= 2009 | volume= 17 | issue= 2 | pages= 139-46 | pmid=18985070 | doi=10.1038/ejhg.2008.206 | pmc=2986064 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18985070  }} </ref>
*In the 1950s, Dr. de Morsier reported various cases of patients with hypogonadism and with absent [[olfactory bulbs]] as well. After which, hypogonadism has been described as [[Gonadotropin deficiency|gonadotropin hormones deficiency]].
*In the 1950s, Dr. de Morsier reported various cases of patients with hypogonadism and with absent [[olfactory bulbs]] as well. After which, hypogonadism has been described as [[Gonadotropin deficiency|gonadotropin hormones deficiency]].



Latest revision as of 19:17, 8 September 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2]

Overview

Hypogonadism was first reported by Dr. Maestre de San Juan in a case of small testes and loss of smelling sensation. Dr. Kallmann in 1944 identified this syndrome which was named on him after that. Dr. de Morsier reported various cases of hypogonadism with absent olfactory bulbs in the 1950s.

Historical perspective

  • In 1856, Dr. Maestre de San Juan was the first one to report a case combining small testes (hypogonadism) and loss of smelling sense in a patient.
  • In 1944, Dr. Kallmann was the first to identify a case combining hypogonadism and anosmia as a syndrome which was named on him after then. He held a study showing the correlation between anosmia and hypogonadism in different families.[1]
  • In the 1950s, Dr. de Morsier reported various cases of patients with hypogonadism and with absent olfactory bulbs as well. After which, hypogonadism has been described as gonadotropin hormones deficiency.

References

  1. Dodé C, Hardelin JP (2009). "Kallmann syndrome". Eur J Hum Genet. 17 (2): 139–46. doi:10.1038/ejhg.2008.206. PMC 2986064. PMID 18985070.

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