Babesiosis laboratory findings: Difference between revisions

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{{Babesiosis}}
{{Babesiosis}}
==Overview==
==Overview==
Babesiosis is easy to diagnose but only if it is suspected.  It will not show up on any routine tests.  It must be suspected when a persons with exposure in an endemic area develops persistent fevers and hemolytic anemia. Babesiosis can be diagnosed by direct examination of the blood (see photo), with [[serology]], or with [[PCR]]-based tests. Other laboratory findings include decreased numbers of [[red blood cells]] and [[platelets]] on [[complete blood count]].
Babesiosis is easy to diagnose but only if it is suspected.  It will not show up on any routine tests.  It must be suspected when a persons with exposure in an endemic area develops persistent [[fevers]] and [[hemolytic anemia]].  
 
==Laboratory Findings==
===Electrolyte and Biomarker Studies===
Babesiosis can be diagnosed by direct examination of the blood, with [[serology]], or with [[PCR]]-based tests. Serologic testing for antibodies provides supporting evidence for a potential infection. Other laboratory findings include decreased numbers of [[red blood cells]] and [[platelets]] on [[complete blood count]].
 
===Microscopy===
In symptomatic people, babesiosis usually is diagnosed by examining blood specimens under a microscope and seeing Babesia parasites inside red blood cells. <ref>http://www.cdc.gov/parasites/babesiosis/diagnosis.html</ref>
 
[[File:Babesiosisbloodsmear.jpeg‎|200px|thumb|center|Microscopic finding of Babesia parasites in red blood cells]]
 
==Gallery==
 
 
<gallery>
 
Image: Babesiosis15.jpeg| Babesia microti in blood smear. Giemsa stain. Parasite. <SMALL><SMALL>''[http://phil.cdc.gov/phil/home.asp From Public Health Image Library (PHIL).] ''<ref name=PHIL> {{Cite web | title = Public Health Image Library (PHIL) | url = http://phil.cdc.gov/phil/home.asp}}</ref></SMALL></SMALL>
 
Image: Babesiosis14.jpeg| Babesia microti in blood smear. Giemsa stain. Parasite. <SMALL><SMALL>''[http://phil.cdc.gov/phil/home.asp From Public Health Image Library (PHIL).] ''<ref name=PHIL> {{Cite web | title = Public Health Image Library (PHIL) | url = http://phil.cdc.gov/phil/home.asp}}</ref></SMALL></SMALL>
 
Image: Babesiosis13.jpeg| Babesia microti in blood smear. Giemsa stain. Parasite. <SMALL><SMALL>''[http://phil.cdc.gov/phil/home.asp From Public Health Image Library (PHIL).] ''<ref name=PHIL> {{Cite web | title = Public Health Image Library (PHIL) | url = http://phil.cdc.gov/phil/home.asp}}</ref></SMALL></SMALL>
 
Image: Babesiosis12.jpeg| Babesia microti in blood smear. Giemsa stain. Parasite. <SMALL><SMALL>''[http://phil.cdc.gov/phil/home.asp From Public Health Image Library (PHIL).] ''<ref name=PHIL> {{Cite web | title = Public Health Image Library (PHIL) | url = http://phil.cdc.gov/phil/home.asp}}</ref></SMALL></SMALL>
 
Image: Babesiosis11.jpeg| Babesia microti in blood smear. Giemsa stain. Parasite. <SMALL><SMALL>''[http://phil.cdc.gov/phil/home.asp From Public Health Image Library (PHIL).] ''<ref name=PHIL> {{Cite web | title = Public Health Image Library (PHIL) | url = http://phil.cdc.gov/phil/home.asp}}</ref></SMALL></SMALL>
 
Image: Babesiosis10.jpeg| Babesia microti in blood smear. Giemsa stain. Parasite. <SMALL><SMALL>''[http://phil.cdc.gov/phil/home.asp From Public Health Image Library (PHIL).] ''<ref name=PHIL> {{Cite web | title = Public Health Image Library (PHIL) | url = http://phil.cdc.gov/phil/home.asp}}</ref></SMALL></SMALL>
 
Image: Babesiosis09.jpeg| Babesia microti in blood smear. Giemsa stain. Parasite. <SMALL><SMALL>''[http://phil.cdc.gov/phil/home.asp From Public Health Image Library (PHIL).] ''<ref name=PHIL> {{Cite web | title = Public Health Image Library (PHIL) | url = http://phil.cdc.gov/phil/home.asp}}</ref></SMALL></SMALL>
 
Image: Babesiosis08.jpeg|Babesia microti in blood smear. Giemsa stain. Parasite. <SMALL><SMALL>''[http://phil.cdc.gov/phil/home.asp From Public Health Image Library (PHIL).] ''<ref name=PHIL> {{Cite web | title = Public Health Image Library (PHIL) | url = http://phil.cdc.gov/phil/home.asp}}</ref></SMALL></SMALL>
 
Image: Babesiosis07.jpeg| This blood smear micrograph reveals a Babesia sp. tetrad formation. <SMALL><SMALL>''[http://phil.cdc.gov/phil/home.asp From Public Health Image Library (PHIL).] ''<ref name=PHIL> {{Cite web | title = Public Health Image Library (PHIL) | url = http://phil.cdc.gov/phil/home.asp}}</ref></SMALL></SMALL>
 
Image: Babesiosis06.jpeg| This blood smear micrograph revealed the presence of Babesia sp. ring formations inside the host erythrocytes. <SMALL><SMALL>''[http://phil.cdc.gov/phil/home.asp From Public Health Image Library (PHIL).] ''<ref name=PHIL> {{Cite web | title = Public Health Image Library (PHIL) | url = http://phil.cdc.gov/phil/home.asp}}</ref></SMALL></SMALL>
 
Image: Babesiosis05.jpeg| This photomicrograph revealed the presence of an "older ring-form" of a Babesia sp. protozoan parasite in a blood smear. This older ring-form was located within an erythrocyte, and was displaying two chromatin masses. <SMALL><SMALL>''[http://phil.cdc.gov/phil/home.asp From Public Health Image Library (PHIL).] ''<ref name=PHIL> {{Cite web | title = Public Health Image Library (PHIL) | url = http://phil.cdc.gov/phil/home.asp}}</ref></SMALL></SMALL>
 
Image: Babesiosis04.jpeg| Blood smear showing large Babesia rings in erythrocytes. <SMALL><SMALL>''[http://phil.cdc.gov/phil/home.asp From Public Health Image Library (PHIL).] ''<ref name=PHIL> {{Cite web | title = Public Health Image Library (PHIL) | url = http://phil.cdc.gov/phil/home.asp}}</ref></SMALL></SMALL>
 
Image: Babesiosis03.jpeg| At a magnification of 1000X, this blood smear photomicrograph revealed the presence of a number of intra-erythrocytic forms of Babesia sp. hemoprotozoan parasites. <SMALL><SMALL>''[http://phil.cdc.gov/phil/home.asp From Public Health Image Library (PHIL).] ''<ref name=PHIL> {{Cite web | title = Public Health Image Library (PHIL) | url = http://phil.cdc.gov/phil/home.asp}}</ref></SMALL></SMALL>
 
Image: Babesiosis02.jpeg| Blood smear showing larger trophic stage of Babesia microti in erythrocyte. <SMALL><SMALL>''[http://phil.cdc.gov/phil/home.asp From Public Health Image Library (PHIL).] ''<ref name=PHIL> {{Cite web | title = Public Health Image Library (PHIL) | url = http://phil.cdc.gov/phil/home.asp}}</ref></SMALL></SMALL>
 
Image: Babesiosis01.jpeg| Note the developmental “tetrad” configuration of these Babesia sp. trophozoites, which resemble P. falciparum. <SMALL><SMALL>''[http://phil.cdc.gov/phil/home.asp From Public Health Image Library (PHIL).] ''<ref name=PHIL> {{Cite web | title = Public Health Image Library (PHIL) | url = http://phil.cdc.gov/phil/home.asp}}</ref></SMALL></SMALL>
 
 
</gallery>
 
==References==
==References==
{{Reflist|2}}
{{Reflist|2}}
[[Category:Parasitic diseases]]
[[Category:Apicomplexa]]
[[Category:Disease]]


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Latest revision as of 17:05, 18 September 2017

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Overview

Babesiosis is easy to diagnose but only if it is suspected. It will not show up on any routine tests. It must be suspected when a persons with exposure in an endemic area develops persistent fevers and hemolytic anemia.

Laboratory Findings

Electrolyte and Biomarker Studies

Babesiosis can be diagnosed by direct examination of the blood, with serology, or with PCR-based tests. Serologic testing for antibodies provides supporting evidence for a potential infection. Other laboratory findings include decreased numbers of red blood cells and platelets on complete blood count.

Microscopy

In symptomatic people, babesiosis usually is diagnosed by examining blood specimens under a microscope and seeing Babesia parasites inside red blood cells. [1]

Microscopic finding of Babesia parasites in red blood cells

Gallery

References

  1. ↑ http://www.cdc.gov/parasites/babesiosis/diagnosis.html
  2. ↑ 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 2.11 2.12 2.13 2.14 "Public Health Image Library (PHIL)".


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