Bazin disease overview: Difference between revisions

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== Overview ==
== Overview ==
'''Bazin disease''' is a skin [[ulceration]] on the back of the [[calve]]s. It was formerly thought to be a reaction to the [[tuberculum bacillus]]. It is very rare now.
'''Bazin disease''' is a skin [[ulceration]] on the back of the [[calve]]s. It was formerly thought to be a reaction to the [[tuberculum bacillus]]. It is very rare now.
==Historical Perspective==
Bazin disease is named for [[Pierre-Antoine-Ernest Bazin]].<ref>{{WhoNamedIt|synd|102}}</ref><ref>P. A. E. Bazin. Leçons théoriques et cliniques sur la scrofule, considérée en ellemême et dans ses rapports avec la syphilis, la dartre et l'arthritis. 2nd edition, Paris, 1861. Page 145 and 501.</ref>
==Pathophysiology==
Bazin disease is a type of [[panniculitis]] characterized histologically by the presence of [[granulomas]], [[vasculitis]], and [[necrosis]].
==Causes==
Bazin disease was formerly thought to be a reaction to [[tuberculum bacillus]], but it is now considered a [[panniculitis]] that is not associated with a single defined pathogen. <ref name="isbn0-7216-0187-1">{{cite book |author=Cotran, Ramzi S.; Kumar, Vinay; Fausto, Nelson; Nelso Fausto; Robbins, Stanley L.; Abbas, Abul K. |title=Robbins and Cotran pathologic basis of disease |publisher=Elsevier Saunders |location=St. Louis, Mo |year=2005 |pages=1265 |isbn=0-7216-0187-1|edition=7th}}</ref>
==Epidemiology and Demographics==
Bazin disease is seen most commonly in [[adolescent]] and menopausal women.
==Risk Factors==
Bazin disease is initiated or exacerbated by cold weather.
==Diagnosis==
===History and Symptoms===
50% of patients will have a past or present history of [[tuberculosis]] at extracutaneous site. Patients typically presents as one or more recurrent erythrocyanotic [[nodules]] or [[plaques]] on the calves.
===Physical Examination===
Patients typically presents as one or more recurrent erythrocyanotic nodules or plaques on the calves.


== References ==
== References ==
Line 11: Line 39:


[[Category:Disease]]
[[Category:Disease]]
[[Category:Infectious disease]]
 
[[Category:Dermatology]]
[[Category:Dermatology]]

Latest revision as of 17:10, 18 September 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Bazin disease is a skin ulceration on the back of the calves. It was formerly thought to be a reaction to the tuberculum bacillus. It is very rare now.

Historical Perspective

Bazin disease is named for Pierre-Antoine-Ernest Bazin.[1][2]

Pathophysiology

Bazin disease is a type of panniculitis characterized histologically by the presence of granulomas, vasculitis, and necrosis.

Causes

Bazin disease was formerly thought to be a reaction to tuberculum bacillus, but it is now considered a panniculitis that is not associated with a single defined pathogen. [3]

Epidemiology and Demographics

Bazin disease is seen most commonly in adolescent and menopausal women.

Risk Factors

Bazin disease is initiated or exacerbated by cold weather.

Diagnosis

History and Symptoms

50% of patients will have a past or present history of tuberculosis at extracutaneous site. Patients typically presents as one or more recurrent erythrocyanotic nodules or plaques on the calves.

Physical Examination

Patients typically presents as one or more recurrent erythrocyanotic nodules or plaques on the calves.

References

  1. Template:WhoNamedIt
  2. P. A. E. Bazin. Leçons théoriques et cliniques sur la scrofule, considérée en ellemême et dans ses rapports avec la syphilis, la dartre et l'arthritis. 2nd edition, Paris, 1861. Page 145 and 501.
  3. Cotran, Ramzi S.; Kumar, Vinay; Fausto, Nelson; Nelso Fausto; Robbins, Stanley L.; Abbas, Abul K. (2005). Robbins and Cotran pathologic basis of disease (7th ed.). St. Louis, Mo: Elsevier Saunders. p. 1265. ISBN 0-7216-0187-1.

Template:WH Template:WS