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==Overview==
==[[Bronchial atresia overview|Overview]]==
'''Bronchial atresia''' is a disorder in which a segmental bronchus fails to connect with or  communicate with the more central airways. <ref>Cohen AM, Solomon EH, Alfidi RJ. Computed tomography in bronchial atresia. American Journal of Roentgenology, 1980;135:1097-99.</ref> <ref>Rappaport DC, Herman SJ, Weisbrod GL. Congenital bronchopulmonary diseases in adults: CT findings. American Journal of Roetgenology, 1994;162: 1295-99. </ref> <ref>Kinsella D, Sissons G, Williams MP. The radiological imaging of bronchial atresia.British Journal of Radiology 1992;65:681-85.</ref> <ref>
Shady K, Siegel MJ, Glazer HS. CT of focal pulmonary masses in childhood. Radiographics, 1992;12:505-514. </ref> <ref>Kuhn C, Kuhn JP. Coexistence of bronchial atresia and bronchogenic cyst: Diagnostic criteria and embryologic considerations. Pediatric Radiology 1992;22:568-70. </ref>


==Pathophysiology and Etiology==
==[[Bronchial atresia historical perspective|Historical Perspective]]==
The underlying basis of the disorder is not clear. It has been hypothesized to be the result of a vascular injury to the lung at approximately 15 to 16 weeks gestation. An alternate hypothesis is that the disorder occurs secondary to separation of the bronchial bud during the 5th to 6th week of gestation. [[Pulmonary sequestration]] and [[bronchogenic cyst]]s also form during this early period of fetal development and may share an underlying pahtophysiology.


The most common anatomic locations include the following:
==[[Bronchial atresia pathophysiology|Pathophysiology]]==
#The apical posterior segment of the left upper lobe
#The left lower lobe
#The right middle lobe


==Epidemiology and Demographcis==
==[[Bronchial atresia causes|Causes]]==
Females outnumber males 2:1.


==Diagnosis==
==[[Bronchial atresia differential diagnosis|Differentiating Bronchial atresia from other Diseases]]==
===Symptoms and History===
The majority of patients are asymptomatic and the mass is discovered as an incidental finding on a routine [[chest X ray]].


If a patient is symptomatic, they complain of [[dyspnea]], [[cough]] and [[wheezing]].
==[[Bronchial atresia epidemiology and demographics|Epidemiology and Demographics]]==


By history the patient may have recurrent pulmonary infections.
==[[Bronchial atresia risk factors|Risk Factors]]==


===Physical Examination===
==[[Bronchial atresia natural history|Natural History, Complications and Prognosis]]==
====Lungs====
Decreased breath sounds may be present in the affected lung fields.


===Chest X Ray===
==Diagnosis==
The chest x ray findings are mucoid impaction of a bronchus yielding a branching tubular mass which is surrounded by hyperinflated lung and decreased vascular markings. The differential diagnosis of these radiographic findings include the following:
[[Bronchial atresia history and symptoms| History and Symptoms]] | [[Bronchial atresia physical examination | Physical Examination]] | [[Bronchial atresia laboratory tests|Laboratory Findings]] | [[Bronchial atresia chest x ray|Chest X Ray]] |  [[Bronchial atresia CT|CT]] | [[Bronchial atresia MRI|MRI]] | [[Bronchial atresia echocardiography or ultrasound|Ultrasound]] | [[Bronchial atresia other imaging findings|Other Imaging Findings]] | [[Bronchial atresia other diagnostic studies|Other Diagnostic Studies]]
#[[Arteriovenous malformation]]
#[[Granuloma]]
#[[Metastases]]
 
===Computed Tomography===
This is the imaging modality of choice for diagnosing bronchial atresia and demonstrates segmental emphysematous changes beyond the mucous impaction in the bronchus.


==Treatment==
==Treatment==
Conservative management is the usual course of treatment. However, if the patient is symptomatic with respiratory compromise or if their course is complicated by recurrent infection, then surgical resection may be helpful.
[[Bronchial atresia medical therapy|Medical Therapy]] | [[Bronchial atresia surgery|Surgery]] | [[Bronchial atresia primary prevention|Primary Prevention]] | [[Bronchial atresia secondary prevention|Secondary Prevention]] | [[Bronchial atresia cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Bronchial atresia future or investigational therapies|Future or Investigational Therapies]]


==References==
==Case Studies==
{{reflist|2}}
[[Bronchial atresia case study one|Case#1]]


[[Category:Pulmonology]]
[[Category:Pulmonology]]
[[Category:Infectious disease]]
 
[[Category:Disease]]


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Latest revision as of 17:15, 18 September 2017

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Overview

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Historical Perspective

Pathophysiology

Causes

Differentiating Bronchial atresia from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms | Physical Examination | Laboratory Findings | Chest X Ray | CT | MRI | Ultrasound | Other Imaging Findings | Other Diagnostic Studies

Treatment

Medical Therapy | Surgery | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

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Case#1


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