Cat scratch fever medical therapy: Difference between revisions
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{{Cat scratch fever}} | {{Cat scratch fever}} | ||
{{CMG}}; {{AE}} {{RT}} | {{CMG}}; {{AE}} {{RT}} | ||
==Overview== | ==Overview== | ||
The majority of cases of cat scratch disease are self limited. [[Antimicrobial]] therapy is administered in select cases and the drug of choice is [[Azithromycin]]. | |||
Most healthy people will clear the infection without treatment, and antimicrobial therapy is not recommended for immunocompetent patients with mild to moderate ''[[Bartonella henselae]]'' disease due to the risk of side-effects from antibiotics. | ==Medical Therapy== | ||
Most healthy people will clear the infection without treatment, and antimicrobial therapy is not recommended for immunocompetent patients with mild to moderate ''[[Bartonella henselae]]'' disease due to the risk of side-effects from antibiotics. [[Azithromycin]], [[Ciprofloxacin]], [[Doxycycline]], and multiple other antibiotics have been used but with unclear benefit.<ref>{{cite journal|last=Rolain|first=J.M.|title=Recommendations for Treatment of Human Infections Caused by Bartonella Species|journal=Antimicrobial Agents and chemotherapy|year=2004|month=June|pages=1921–1933|pmid=15155180|doi=10.1128/AAC.48.6.1921-1933.2004|pmc=415619|volume=48|issue=6}}</ref> | |||
* Cat scratch disease<ref name="pmid24947530">{{cite journal| author=Stevens DL, Bisno AL, Chambers HF, Dellinger EP, Goldstein EJ, Gorbach SL et al.| title=Practice guidelines for the diagnosis and management of skin and soft tissue infections: 2014 update by the infectious diseases society of America. | journal=Clin Infect Dis | year= 2014 | volume= 59 | issue= 2 | pages= 147-59 | pmid=24947530 | doi=10.1093/cid/ciu296 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24947530 }} </ref> | |||
:* '''Cat scratch disease in patients > 45 kg''' | |||
::* Preferred regimen: [[Azithromycin]] 500 mg PO on day 1 {{and}} 250 mg PO for additional 4 days | |||
:* '''Cat scratch disease in patients < 45 kg''' | |||
::* Preferred regimen: [[Azithromycin]] 10 mg/kg PO on day 1 {{and}} 5 mg/kg PO for 4 more days | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
[[Category:Disease]] | |||
[[Category:Bacterial diseases]] | |||
[[Category:Zoonoses]] | |||
[[Category: Infectious Disease Project]] | |||
{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} | ||
Latest revision as of 17:19, 18 September 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Raviteja Guddeti, M.B.B.S. [2]
Overview
The majority of cases of cat scratch disease are self limited. Antimicrobial therapy is administered in select cases and the drug of choice is Azithromycin.
Medical Therapy
Most healthy people will clear the infection without treatment, and antimicrobial therapy is not recommended for immunocompetent patients with mild to moderate Bartonella henselae disease due to the risk of side-effects from antibiotics. Azithromycin, Ciprofloxacin, Doxycycline, and multiple other antibiotics have been used but with unclear benefit.[1]
- Cat scratch disease[2]
- Cat scratch disease in patients > 45 kg
- Preferred regimen: Azithromycin 500 mg PO on day 1 AND 250 mg PO for additional 4 days
- Cat scratch disease in patients < 45 kg
- Preferred regimen: Azithromycin 10 mg/kg PO on day 1 AND 5 mg/kg PO for 4 more days
References
- ↑ Rolain, J.M. (2004). "Recommendations for Treatment of Human Infections Caused by Bartonella Species". Antimicrobial Agents and chemotherapy. 48 (6): 1921–1933. doi:10.1128/AAC.48.6.1921-1933.2004. PMC 415619. PMID 15155180. Unknown parameter
|month=ignored (help) - ↑ Stevens DL, Bisno AL, Chambers HF, Dellinger EP, Goldstein EJ, Gorbach SL; et al. (2014). "Practice guidelines for the diagnosis and management of skin and soft tissue infections: 2014 update by the infectious diseases society of America". Clin Infect Dis. 59 (2): 147–59. doi:10.1093/cid/ciu296. PMID 24947530.